Sentences with word «cilium»

Nicholas Katsanis of Johns Hopkins University in Baltimore, Maryland, and his colleagues, who have studied the role of cilia in human disease, wondered whether the organelles might be involved in higher order touch sensations.

The study shows lithium chloride, a drug often used to treat bipolar disorder, can increase the size of primary cilia in several cell types.

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls genes involved in human ciliopathies.

The sponge's cells, its calcium carbonate or glasslike silica spicules, and the mass of collagen that forms its visible body all create a network of tunnels and chambers, with little flailing hairs called cilia on the walls that wave the water through and filter out plankton and waste.

The arrow points to a site of ectopic cilia on the inside surface of the upper lid of this young Golden Retriever.

When fresh air was passed into the chamber, the researchers observed a 3 per cent drop in cilia beating frequency relative to the baseline value.

He got his first filmmaking experience while he was working on his biology doctorate at the University of Southampton in the U.K., when his advisor decided to make a teaching film on cilia as a showpiece for his work.

Katsanis and his colleagues also tested nine patients with Bardet - Biedl syndrome, who have genetic mutations that affect cilia function.

In a report published on September 30 in Nature Genetics, Katsanis and his team used a small transparent fish, zebrafish, to literally watch what happened if they chemically blocked the production of three proteins that are required for primary cilia function during the period when a fish egg develops into a grown up, fully - finned fish.

Finding out just what cilia do in the brain is a tough job, Mykytyn says.

Neurologist Kazunobu Sawamoto at Keio University in Japan and an international team of his colleagues used fluorescent dye and India ink to trace the flow of spinal fluid in mice and found that it followed the whiplike waving of hairlike projections known as cilia from cells lining the route.

When the scientists looked in the brain of a mouse with this mutation, they found, again, that MC4R was not on the nerve cell cilia where it should go to work.

These findings suggest mice need healthy cilia for normal memories.

Now, a new study from University of Georgia cellular biologists shows the mechanism behind tubulin transport and its assembly into cilia, including the first video imagery of the process.

Three of the ray species have filters with layers of hair like cilia to capture food, the rest do not.

Exposure of the epithelial monolayer to an apical fluid shear stress (0.2 dyne cm 2) that mimics that found in living kidney tubules results in enhanced epithelial cell polarization and primary cilia formation compared to traditional Transwell culture systems.

© Wim van Egmond (Photo from Ciliates, used with permission) As the level of oxygen in the atmosphere rose, however, most surface lifeforms on Earth became oxygen breathing, such as these two single - celled protoctists (Euplotes, left, and Stylonychia) which move with hairlike cilia.

Then, the tiny hairs in the respiratory tract called cilia help to sweep up the infected mucus like little brooms, says Dr. Elliott, so we can cough or blow it out.

Soft, fine, tapered or silky cilia which float in the tear film usually do not cause irritation.

Understanding how cilia become dysfunctional in these diseases could provide insight into how to better treat or prevent them.

These mice also didn't recognize objects as well as did those with normal cilia.

The fluid shear stress sensed by the primary cilium at the apical cell surface is responsible for the induction of autophagy.

Sensory cilia did not come from random mutations.

«Previous studies from our group show how the length of primary cilia play a role in stem cell differentiation, and this current study provides further insight.

The pathogens temporarily destroy the protective cilia lining of the trachea, larynx and bronchi.

New structures discovered within cilia show a relationship between certain proteins and juvenile myoclonic epilepsy.

Still, the new study «opens up the window a little more» on what cilia actually do in the brain, says Nick Berbari.

Scientists are still sorting out exactly how cilia work, but some researchers theorize that they act as a cellular antenna, picking up both chemical and mechanical signals from the world outside.

Professor Colin A. Johnson, Professor of Medical and Molecular Genetics in the School of Medicine at the University of Leeds, said: «This research gives us the best list yet of the human genes needed to make cilia.

Venezuela's President Nicolas Maduro and his wife Cilia Flores smile upon their arrival at a campaign rally in Ciudad Guayana, Venezuela April 23, 2018.

Monk notes, however, that other studies have shown that the swishing cilia also influence calcium concentrations, and it is possible that a similar effect is at work in developing mice.

Also called immotile cilia syndrome and Kartagener's syndrome.

A rare immune system disease called immotile cilia syndrome (or Kartagener's syndrome) can occur in Bichons.

The saline solution, prepared with 8 ounces distilled water and 1⁄2 tsp non-iodized mineral or sea salt, helps tiny hair - like structures called cilia sweep out dust, germs, allergens, and mucus.

The fluid vortex shown is generated by cilia covering the coral's surface, creating a whirlpool structure in the surrounding seawater.

Dysfunctional cilia are now known to be implicated in not only PKD but a wide range of diseases affecting the eyes, ears, heart, and other organs.

The ophthalmology service at the Institute of Veterinary Specialists provides consultation, diagnostic evaluation and treatment pertaining to all aspects of ocular disease in small and large animal patients including cataract surgery, cherry eye repair, corneal surgery and grafting, distichia and ectopic cilia removal, entropion and ectropion surgery, eyelid tumor reconstructive surgery, glaucoma and lens luxation surgery.

Professor Ronald Roepman, of the Radboud University Medical Center, Nijmegen, added: «We confirmed that each of the genes on the list were important for cilia using an independent method.

Pathologists have noticed that nasal cilia continue to pulse for up to 21 hours after «their» human has died.

Biagio Solarino of the University of Bari in Italy and his colleagues suspected that cilia continue to beat after death.

As the sub approaches to scrape a sample from them, crew - member Kevin Hand spots something otherworldly: a translucent, spaceship - like creature, its iridescent cilia pulsing gently as it passes through the rover's headlights.

Dense canopies of cilia cover the polyps and stir the fluid layer in the immediate vicinity.

Loss of Alix (right) also results in defective orientation of motile cilia in the ependyma — the protective epithelial barrier between brain and cerebrospinal fluid.

Defective cilia can lead to kidney disease and obesity (Science, 14 October 2005, p. 216).

Additional BTI researchers on the project include co-first authors and postdoctoral researchers Wenbo Chen and Daniel Hasegawa; Cornell graduate students Patricia Valle Pinheiro and Angela Kruse; postdoctoral scientist Yi Zheng; visiting scholar Wenli Liu; bioinformatics analyst Honghe Sun; research specialist Yimin Xu; Professor Georg Jander and Assistant Professor Michelle Cilia.

Runner up: Danielle Dixon, Mueller / Cilia labs, «Elucidating genetic variation in «Candidatus Liberibacter asiaticus» transmission between Asian citrus psyllid isofemale lines»

Although data show the MC4R protein must reach cilia to control appetite, Mykytyn points out that no one knows why.

A series of biochemical studies revealed that cilia normally help a cell keep the right balance by selectively destroying proteins in the canonical branch to prevent excess growth.