Sentences with phrase «circadian clocks work»

Brooks plans to unravel how the circadian clock works with the innate immune system to regulate microbe metabolism.

Not exact matches

The pair realized once they had achieved an early working prototype that if the goal was to reset circadian rhythms to improve sleep, they needed accurate sleep data and a model of a user's body clock.

Though they're casting a wide net, she adds that «one of hundreds of things we'd be interested in seeing is more work on the role of the circadian or other developmental clocks in longevity.»

Disruption of the circadian clock in humans is a hallmark of relatively recent lifestyle changes involving chronic shift work or frequent flights across time zones.

Mammals, humans included, have circadian clocks that work with the same logic and many of the same gears found in fruit flies, say Jennifer Loros and Jay Dunlap, geneticists at the Geisel School of Medicine at Dartmouth College.

The expert is the author of a study published in the «International Journal of Cancer», which reveals the importance of assessing how the circadian system works in order to prevent chronodisruption and to implement measures to strengthen the biological clock in people whose system is damaged.

«This study adds to an important body of work that has shown the ubiquity of a circadian clock across species, including humans, and its role in metabolic regulation in cells, organs, and organisms,» said Dr. Michael Sesma, Program Director in the Division of Genetics and Developmental Biology at the of the National Institutes of Health's National Institute of General Medical Sciences, which partially funded the research.

During the 62nd Biophysical Society Annual Meeting, held Feb. 17 - 21, in San Francisco, California, Andy LiWang at the University of California, Merced will present his lab's work studying the circadian clock of blue - green colored cyanobacteria.

What is more, they transfer day - night information from the circadian clock to such brain areas that control complex behaviours such as orientation to the sun, temporal memory and organizing the work throughout the day.

Because humans have the «identical circadian clock machinery» as mice, adds Bass, the work has important implications for scientists studying obesity and diabetes in people.

Employers, particularly those who operate around the clock, also fail to recognise that their work routines inevitably reduce the effectiveness of their workers, says Charles Czeisler, director of the Laboratory for Circadian and Sleep Disorders Medicine at Brigham and the Women's Hospital in Boston.

Also featured in the report is the work of Michele Pagano on the circadian clock.

Humans can overrule their body clocks, but at a price: People whose circadian rhythms are regularly disrupted — by frequent jet lag or shift work, for example — are more vulnerable to diabetes, obesity, cardiovascular disease, and cancer.

The Physiology or Medicine Prize recognized work on how several genes work together to control the basic circadian clock, encoding proteins that build up during the night and are broken down during the day.

Jeffrey Hall and Michael Rosbash of Brandeis University in Waltham, Massachusetts, and Michael Young of The Rockefeller University in New York City share the prize equally for their work on how several genes work together to control the basic circadian clock, encoding proteins that build up during the night and are broken down during the day.

Early work in plants and insects had, in fact, established the existence of such body clocks, but it wasn't until the mid-1980s that the researchers, two of whom were collaborators, uncovered the inner molecular workings behind this basic process, called a circadian rhythm.

Early work in plants and insects had, in fact, established the existence of such circadian clocks, but it wasn't until the mid-1980s that the researchers uncovered the inner molecular workings behind this basic process.

Clock genes keep circadian rhythms in sync, coordinating cells» essential work and possibly enhancing well - timed therapies.

«Important metabolic functions are also heavily influenced by circadian clocks, which is why activities such as chronic night - shift work — which can cause a misalignment of this clock — increase one's risk for metabolic and autoimmune diseases such as obesity, Type 2 diabetes, cancer and multiple sclerosis,» said Dr. Akassoglou.

«We are currently working to identify the relationship between the circadian clock, metabolism and the immune system, so that one day we could develop therapies to treat diseases influenced by circadian clock disruption — including not only obesity and diabetes, but also potentially multiple sclerosis and even Alzheimer's disease.»

Nothing good, say scientists exploring what appears to be a direct connection between a circadian clock that isn't working as it should and an enzyme that promotes inflammation working overtime.

This new understanding of how circadian rhythms are regulated through the eye could open up new therapeutic possibilities for restoring biological clocks in people who have jet lag through travelling or working night shifts.

Sancar is also known for his work uncovering the inner workings of the circadian clock — a group of enzymes that keep us in proper rhythm with the 24 - hour day and the four seasons.

But when your body clock is disrupted or thrown out of balance by occasional or continuous interruptions of sleeping patterns, changes in light exposure, working the night shift regularly or other disruptions in your schedule, your natural circadian rhythms can become accelerated or slowed, leading to a cascade of physiologic impacts.

Though they're casting a wide net, she adds that «one of hundreds of things we'd be interested in seeing is more work on the role of the circadian or other developmental clocks in longevity.»