Sentences with phrase «circadian gene expression»

His research is focused on understanding how environmental factors, such as nutrients and light, influence circadian gene expression and the processes of aging.

Not exact matches

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24 - hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA - protein complex of the cell.

CLOCK is an acronym for «Circadian Locomotor Output Cycles Kaput,» because it is a central regulator of gene expression related to the body's circadian rhythm of sleeping anCircadian Locomotor Output Cycles Kaput,» because it is a central regulator of gene expression related to the body's circadian rhythm of sleeping ancircadian rhythm of sleeping and waking.

However, very little is known about how the circadian clock regulates this critical part of gene expression to organize the day - night rhythm of protein expression, and if the formation of this looping changes over the day.

Mutations of miR - 182 have been associated with a wide range of disorders, including insomnia and depression, and elevated expression appears to impact genes that regulate the body's circadian rhythm.

But when the UPR was chemically activated, Bmal1 stayed low during both light and dark phases, which caused a phase shift in the expression of circadian genes.

The expression of core clock genes is altered in mice lacking the Chrono gene, and the mice have longer circadian cycles.

«The disruption of the circadian clock machinery seems to affect not only the rhythm of appetite regulation, but also the expression of the genes and proteins at their absolute level,» says Turek, whose team reports its findings online today in Science.

For example, for decades, circadian rhythms in the mammalian gastrointestinal system were studied in the context of human physiology and gene expression.

A. Sehgal et al., «Rhythmic expression of timeless: A basis for promoting circadian cycles in period gene autoregulation,» Science 270, 5237 (3 November 1995)

Circadian genes turned out to be also infradian genes, whose expressions go up and down with mood - change - like behaviors in these mice,» Miyakawa explains.

We measured gene expression of Cry1, Cry2 and Cry4 in the retina, muscle and brain of zebra finches over the circadian day to assess whether they showed any circadian rhythmicity.

12:00 PM MBD5 - associated intellectual disability: A methyl - binding protein that regulates target gene expression affecting circadian, developmental, and neurological pathways.

Cyanobacteria possess one of the simplest known circadian clocks — the KaiABC system, a complex of proteins that undergoes a 24 - hour biochemical cycle, which triggers oscillations in gene expression and physiological activity.