Sentences with phrase «circadian genes»
"Circadian genes" refers to specific genes in our body that regulate our internal body clock, or circadian rhythm. These genes control our sleep-wake cycle, metabolism, hormone production, and other biological processes that occur over a 24-hour day. They help us stay in sync with the natural day-night cycle and maintain our overall bodily functions. Full definition
This image illustrates concepts in the press release titled «Infradian oscillation of circadian genes in a mouse model of bipolar disorder».
sciencedaily.com
«Infradian oscillation of circadian genes in a mouse model of bipolar disorder.»
This work will initiate new awareness of circadian gene expression changes in aging and dietary restriction studies and contribute to the sub-discipline of «chronogerontology».
What we need to do now is to see if other circadian gene variants in association with different stress factors cause the same effect.
«Financial stress is associated with migraine, if you have specific circadian gene variants.»
Coactivator - Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude through REV - ERB Loading.
The authors characterize a new circadian gene that they name Chrono.
At the end of 3 weeks, when the volunteers were waking up about 4 hours later than they used to, the activity of their hair follicle circadian genes had shifted too — but only by about two and a half 2 1/2 hours, the team reports online today in the Proceedings of the National Academy of Sciences.
When they extracted RNA from these cells, they found that circadian gene activities peaked when volunteers were awake and alert, and it peaked earliest in the volunteer who woke up earliest in the morning.
Circadian genes turned out to be also infradian genes, whose expressions go up and down with mood - change - like behaviors in these mice,» Miyakawa explains.
His research is focused on understanding how environmental factors, such as nutrients and light, influence circadian gene expression and the processes of aging.
Polymorphisms in many circadian genes mimic certain aspects of self - induced circadian arrhythmia (ie, skipping breakfast & eating late at night, not getting enough light in the morning & too much in the evening, etc.)... it kills me when I hear about kids playing on their iPads & smart phones late at night.
In the initial report, mice harboring a mutation in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2).
Our preliminary data demonstrates that DR enhances the amplitude of circadian genes and may inhibit the age - relate decline in loss of circadian homeostasis.
Specifically, the regular oscillations of other circadian genes in the brain and the liver became disrupted, as well as genes known to regulate glucose and lipid metabolism.
But when the UPR was chemically activated, Bmal1 stayed low during both light and dark phases, which caused a phase shift in the expression of circadian genes.
Variations of circadian genes (which affect how the body controls and responds to environmental changes — such as changes in light) have previously been shown to affect mood disorders, so it was thought it would be interesting to see if they were associated with migraine.
Scientists compared urination patterns, both volume and frequency, in normal mice and in mice genetically engineered without two circadian genes, Cryptochrome - 1 and Cryptochrome - 2, resulting in dysfunctional circadian rhythms.
They found that a circadian gene called Rev - erbα controlled the production of Cx43, a protein that determines how much urine bladders hold.
«To our surprise, the list of «prediction genes» included significantly higher number of circadian genes, genes that are known to fluctuate according to circadian rhythms.
Interestingly, so - called circadian genes, whose expressions increase and decrease over a 24 - hour cycle, are overrepresented in the prediction gene sets, demonstrating an intrinsic link between circadian genes in the brain and mood change - like behavior.
Researchers also found that levels of cAMP and pCREB, possible upstream regulators of some circadian genes, were correlated with locomotor activity.
«The current results provide the evidence for a novel concept that some circadian genes and their regulatory machinery in the brain may be involved in the generation of infradian rhythm behavior,» Miyakawa explains.
The researchers wanted to see if there was a connection between these circadian genes and p75NTR.