Sentences with phrase «circadian genes in a mouse»

This image illustrates concepts in the press release titled «Infradian oscillation of circadian genes in a mouse model of bipolar disorder».

Not exact matches

In 1997 Joseph Takaha - shi of the Howard Hughes Medical Institute at Northwestern University and his colleagues isolated a gene they called Clock that when mutated yielded mice with no discernible circadian rhythm.

These four genes and their proteins constitute the heart of the biological clock in flies, and with some modifications they appear to form a mechanism governing circadian rhythms throughout the animal kingdom, from fish to frogs, mice to humans.

In recent years, clock researchers have uncovered some of the gears and springs that keep this circadian timepiece running, largely by identifying a handful of key genes in organisms from bread mold to micIn recent years, clock researchers have uncovered some of the gears and springs that keep this circadian timepiece running, largely by identifying a handful of key genes in organisms from bread mold to micin organisms from bread mold to mice.

Scientists compared urination patterns, both volume and frequency, in normal mice and in mice genetically engineered without two circadian genes, Cryptochrome - 1 and Cryptochrome - 2, resulting in dysfunctional circadian rhythms.

The expression of core clock genes is altered in mice lacking the Chrono gene, and the mice have longer circadian cycles.

In mice heterozygous for tau - lacZ targeted to the melanopsin gene locus, β - galactosidase — positive RGC axons projected to the SCN and other brain nuclei involved in circadian photoentrainment or the pupillary light refleIn mice heterozygous for tau - lacZ targeted to the melanopsin gene locus, β - galactosidase — positive RGC axons projected to the SCN and other brain nuclei involved in circadian photoentrainment or the pupillary light reflein circadian photoentrainment or the pupillary light reflex.

The researchers also found that genes related to circadian rhythms (the body clock) were changed in mice exposed to e-cigarettes.

A study in mice has found that variations in a gene that regulates the circadian clock seem to increase the chances of breast cancer spreading.

Looking at mice with differing risks of metastasis, Kent Hunter at the National Cancer Institute in Bethesda, Maryland, and his team found a circadian rhythm gene, Arntl2, seemed to be involved.

Circadian genes turned out to be also infradian genes, whose expressions go up and down with mood - change - like behaviors in these mice,» Miyakawa explains.

PER2: Deletion of the PER2 gene in mice, associated with the mechanisms of circadian rhythm, appears to improve DNA repair in stem cell populations relevant to the immune system, resulting in a healhier immune cell population, better immune function in old age, and a modestly extended life span.

Mice lacking molecular - clock components (Per and Cry), or lacking Per genes in osteoblasts, display high bone mass, suggesting that bone remodeling may also be subject to circadian regulation.

In the initial report, mice harboring a mutation in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2In the initial report, mice harboring a mutation in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2in the core circadian gene Clock (termed Clock mutant mice) were fed a high - fat (HF) diet and observed to develop obesity at a young age, as well as a variety of metabolic and endocrine abnormalities consistent with the metabolic syndrome (2).