Sentences with phrase «circuit formation»
My lab is currently moving our interest in retinal circuit formation in a new and related direction: how these circuits need to be protected over time to ensure proper visual function.
brightfocus.org
And, it includes brain circuit formation as well as processing speed of the brain.
Understanding the process of activity - dependent circuit formation and regulation will have a significant impact on the basic and clinical scientific communities.
«Because our findings implicate the earliest stages of cortex circuit formation in a mouse model, they suggest that the pathological changes leading to autism might start before birth in humans.»
His career was at first devoted to neuronal cell biology, but during his postdoctoral work at Harvard Medical School, he decided to shift to the challenging question of how gene regulation programs control circuit formation in the brain.
In the developing brain, α4β2 and α7 subtypes of the nAChR have been implicated in neuronal proliferation, apoptosis, migration, differentiation, synapse formation, and neural - circuit formation [14], [15].
We employ genetic tools in an attempt to understand the contribution of mGluR5 signaling in specific neuronal populations to sensory circuit formation, synaptic function / plasticity, and behavior.
Carlos J. Ballester Rosado, Michael J Albright, Chia - Shan Wu, Chun - Chieh Liao, Jie Zhu, Shen - Ju Chou, Dennis D O'Leary, Li - Jen Lee, and Hui - Chen Lu (2010) «mGluR5 in cortical excitatory neurons exerts both cell autonomous and nonautonomous influences on cortical somatosensory circuit formation», Journal of Neuroscience, 30:16896 - 909.
Understanding the effects of endocannabinoids during neural circuit formation will not only shed light on normal brain development and function but will also allow us to assess endocannabinoid - based therapies and the effects of cannabis use on the developing fetus.
System 1: The basal ganglia, which helps strengthen the speed of circuit formation, and the sensory cortex are major players.
«The immediate implications of this study are for diseases of motor neurons, like ALS, but I think our findings might also apply more generally to diseases of neural - circuit formation in the brain such as autism, schizophrenia and epilepsy,» Molofsky said.
Additionally, they found the number of neurons stimulated, but not the physical distance among the neurons, was a factor in circuit formation.
Our goal is to characterize some of the molecular and cellular mechanisms involved in the local regulation of the energy metabolism in the axon during the embryonic and postnatal development, and to understand the consequences of disrupting the energy metabolism of developing neurons on axon development and circuit formation in the mouse.
He joined the Polleux lab in 2014 where he studies the role of SRGAP2A and its human - specific paralog SRGAP2C in synaptic development and circuit formation.