Iacoboni is best known for his work studying mirror neurons, a small
circuit of cells in the brain that may be an important element of social cognition.
Not exact matches
By collecting sequencing information about
cells in the gut, for example, Kallyope can better figure out how they're connected to neurons
in the
brain in a series
of circuits.
The infrastructure mediates inheritance (for instance,
in cell division or
in the repetition
of similar
circuit patterns
in the excitation
of the
brain), and inheritance thus has
in it that same discontinuity.
We're funding researchers to investigate how drugs alter what genes are activated such that they modify the function
of the
cells, and how this,
in turn, modifies the functions
of brain circuits, and how that modifies behavior.
Knowing how these
cells mature during development might lead to a better grasp
of just how to replicate that process
in the adult
brain, which could eventually pave the way to strategies that rejuvenate aging
circuits, Donato said.
Gaiti Hasan's team from NCBS has now uncovered how this happens — the researchers have discovered an integrative
circuit of nerve
cells in fruit fly
brains that allows them to ignore the lack
of proteins
in their food to enter the pupal stage.
Astrocytes are star - shaped
cells in our
brain that surround
brain neurons, and neural
circuits, protecting them from injury and enabling them to function properly —
in essence, one
of their main roles is to «baby - sit» neurons.
USE it or lose it: a class
of immune
cell demolishes idle
circuits and connections
in the
brain, even a healthy one.
Researchers are also developing rudimentary models
of signaling networks
in cells and simple
brain circuits.
He plans to continue using optogenetics to pin down
circuits of brain cells responsible for disease and to combine that knowledge with the colorful
circuit images to home
in on which wires need to go where to establish normal communication.
Injury to the
brain stimulates the production of new neurons, but these new cells are sometimes hyperexcitable, disrupting neural circuits and causing recurring seizures, researchers with UT Southwestern's Texas Institute for Brain Injury and Repair reported in Nature Communicat
brain stimulates the production
of new neurons, but these new
cells are sometimes hyperexcitable, disrupting neural
circuits and causing recurring seizures, researchers with UT Southwestern's Texas Institute for
Brain Injury and Repair reported in Nature Communicat
Brain Injury and Repair reported
in Nature Communications.
The group employed various viral tracing methods — infecting receptor - expressing neurons with a virus strain and watching them spread as they label infected
cells with a fluorescent protein — to visualize the neural
circuit downstream
of the ESP1 receptor, as well as providing an image
of nerve fibers belonging to specific neurons
in the
brain and synapses relaying impulses from neuron to neuron, to map the anatomical foundation that conveys ESP1 signals
in the
brain.
In the adult
brain, space and orientation are represented by an elaborate hippocampal - parahippocampal
circuit consisting
of head - direction
cells, place
cells, and grid
cells.
Understanding how networks
of cells in circuits work together to give rise to behaviors, thoughts, and emotions requires new technology, he said, and optogenetics is starting to provide new approaches for mapping and repairing the
brain.
In addition, the two genes are turned on in areas that are part of the cortico - striatal - thalamo - cortical circuit, a loop of brain cells connecting the cortex to specific regions involved in processing emotions and movemen
In addition, the two genes are turned on
in areas that are part of the cortico - striatal - thalamo - cortical circuit, a loop of brain cells connecting the cortex to specific regions involved in processing emotions and movemen
in areas that are part
of the cortico - striatal - thalamo - cortical
circuit, a loop
of brain cells connecting the cortex to specific regions involved
in processing emotions and movemen
in processing emotions and movement.
«We're interested
in learning more about what other proteins LRP6 interacts with, as well as how it acts
in different types
of brain cells at different developmental stages
of circuit development and refinement.»
This study, led by Garret D. Stuber, PhD, associate professor
of psychiatry and
cell biology & physiology, and Jenna A. McHenry, PhD, a postdoctoral research associate
in Stuber's lab, identified a hormone - sensitive
circuit in the
brain that controls social motivation
in female mice.
Scientists studying
brain diseases may need to look beyond nerve
cells and start paying attention to the star - shaped
cells known as «astrocytes,» because they play specialized roles
in the development and maintenance
of nerve
circuits and may contribute to a wide range
of disorders, according to a new study by UC San Francisco researchers.
Amita Sehgal, PhD, a professor
of Neuroscience at the Perelman School
of Medicine, University
of Pennsylvania, describes
in Cell a
circuit in the
brain of fruit flies that controls their daily, rhythmic behavior
of rest and activity.
Researchers from the RIKEN - MIT Center for Neural
Circuit Genetics have found that light stimulation
of brain cells can recover memories
in mice with Alzheimer's disease - like memory loss.
In the
brains of humans and non-human primates, over 100 billion nerve
cells build up complicated neural
circuits and produce higher
brain functions.
The goal
of the Huberman Lab is to understand how the retinal and
brain circuits that underlie vision wire up during development and to develop new strategies to monitor, prevent, and treat retinal ganglion
cell loss
in glaucoma.
«
In all these cases, a molecular description
of a
cell that is integrated with [its] electrical and
circuit properties... has remained elusive,» says Boyden, who is a member
of MIT's Media Lab and McGovern Institute for
Brain Research.
In the
brains of humans and non-human primates, over 100 billion nerve
cells build up complicated neural
circuits and produce...
«Deficient neuron - microglia signaling results
in impaired functional
brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood
Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks
in the mouse
brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect
of orexin - 1 and crf - 1 antagonism on stress
circuits: a fMRI study
in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization
of hydrophobic iron oxide nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.
Experts suspect the disorder is caused by abnormalities
in certain areas
of the
brain, the
circuits that connect them, and the neurotransmitters (
brain chemicals) that transmit messages among
brain cells.
Describing the
brain as a big
circuit board
in which each new experience creates a new
circuit, Hopkins neuroscience professor Richard Huganir, Ph.D. says that he and his team found that during emotional peaks, the hormone norepinephrine dramatically sensitizes synapses - the site where nerve
cells make an electro - chemical connection - to enhance the sculpting
of a memory into the big board.
We know a great deal about the genomic mechanisms through which androgens and estrogens influence behavior; by turning genes on and off and thus affecting levels
of proteins
in cells, they slowly sculpt the
brain circuits and peripheral structures required to produce social output.
Using genetic tools to turn on and off different parts
of the
brain, the scientists were able to identify specific
brain circuits and neurons (
brain cells) involved
in the food coma experience.
By accelerating the development and application
of innovative technologies, researchers will be able to produce a revolutionary new dynamic picture
of the
brain that, for the first time, shows how individual
cells and complex neural
circuits interact
in both time and space.
Each need originates from nerve - based
circuits in the
brain that connect electrochemical signals, meaning nerve
cells transmit messages to each other until specific parts
of your body receive the information needed to perform the behavior to get your need met.