Hypoglycaemia damages the brain because brain activity relies on
the circulating glucose as its main energy source.45 46 Thus, NSE decreased with increasing FBG (FBG < 6.0 mmol / L) in contrast to the positive association for FBG > 6.0 mmol / L.
Extrapolated to conditions of postprandial elevation in blood glucose and insulin (particularly after a high - carbohydrate meal), de novo lipogenesis in skeletal muscle, like in the liver, could also contribute to blood glucose homeostasis by disposing some of the excess
circulating glucose as muscle triglycerides, particularly if the glycogen stores are full.
In a patient with insulin resistance, the muscles can not take up
circulating glucose as efficiently as they should.
Not exact matches
Carbs are broken down and stored
as glucose in the muscles and liver, fats are
circulated as triglycerides in the blood stream and stored
as adipose tissue (i.e. body fat).
It appears that
as well
as the state of ketosis and the neuroprotective role that ketone bodies generally display, the lower
glucose levels,
as well
as other
circulating fatty acids i.e. PUFAs also contribute to the anti-seizure effect (8)
Artificial sweeteners will raise insulin which will stay
circulating in the blood
as there is no
glucose for it to break down.
High
circulating blood
glucose can bring about many problems such
as eye and kidney disease.
This is because some of those carbs that are converted to fats wind up being deposited first the liver, then in organs and tissue around the waistline creating «bellyfat» (or,
as Dr. William Davis terms it «Wheatbelly» due to the particularly insidious
glucose spike caused by wheat consumption) while the rest of those VLD's and Triglycerides are spit out and
circulating in the bloodstream and wind up on your blood panel!
Insulin also tells the liver to stop making
glucose and the muscles to store fat (
as there is sufficient energy
circulating in the blood
as glucose).
This type of diet also keeps your brain functioning well
as the brain runs off of
glucose, (ketones too which will be discussed later), and you should have plenty stored in your liver and
circulating in your blood to provide adequate sugar.
As expected, the lower - carbohydrate diet resulted in significantly greater levels of
circulating ketones (∼ 3 mmol / l), which was strongly associated with a lower hepatic
glucose output.
In a longer study35 obese T2D individuals were prescribed a well - formulated ketogenic diet for 56 weeks, and significant improvements in both weight loss and metabolic parameters were seen at 12 weeks and continued throughout the 56 weeks
as evidenced by improvements in fasting
circulating levels of
glucose (− 51 %), total cholesterol (− 29 %), high - density lipoprotein — cholesterol (63 %), low - density lipoprotein — cholesterol (− 33 %) and triglycerides (− 41 %).
Fructose also fails to reduce the amount of
circulating ghrelin (a hunger - signaling hormone)
as much
as glucose does.
It would seem that there is probably exogenous insulin
circulating in my body all throughout the day
as it is the only way I can keep any semblance of
glucose control, even on a very low carb diet.
Glucose is replenished much faster than glycogen, but
as it
circulates the blood, it must be moved into the muscle cells through an insulin mediated process in order to be used.
After a meal, for example, levels of triglycerides and
glucose initially rise; then they gradually decline
as the body removes and stores the nutrients delivered by
circulating blood.