Sentences with phrase «circulating strains of»

Antiviral flu medications like Tamiflu, Relenza and Rapivab also remain quite effective against all circulating strains of flu.

They are created by a computer program to optimally reflect the known circulating strains of HIV.

Each year the World Health Organization (WHO), comparing genetic sequence and antigenic data, makes recommendations about which circulating strains of influenza will make the best matching vaccine.

Since December, an outbreak of swine flu in India has killed more than 1,200 people, and a new MIT study suggests that the strain has acquired mutations that make it more dangerous than previously circulating strains of H1N1 influenza.

These included the past two flu seasons in which vaccines offered only limited protection against the most widely circulating strain of influenza A.

Human placental cell line Jeg - 3 can be readily infected by a circulating strain of Zika virus (left panel) and completely protected by treatment with nanchangmycin (right panel).

Despite rigorous modeling practices, the virus in the vaccine occasionally doesn't match the circulating strain of influenza.

Not exact matches

A part of the research will include analyzing exactly why this year's flu vaccine proved so ineffective against the most common strains circulating (the shot was just 25 % effective against influenza A strains).

We found that the mutations in two amino acids out of more than 300 in one key region of the hemagglutinin protein were enough to lower efficacy to 19 percent against all circulating strains.»

Flu vaccines work by introducing a killed version of circulating virus strains, which trains the body's immune system to recognize and attack similar invaders in the future.

«There were a couple of these in the vaccine strain the past two seasons that wound up making it a little bit different from the actual circulating virus strain.»

Genetic analyses of locally circulating distemper strains published in July 2017 suggest the injectable distemper vaccines should work for the Ethiopian wolves, Fooks says.

The study also confirms that the «H1» hemagluttinin protein of the new virus derives from the classical swine H1N1 strain, which shares a close common ancestor with the human H1N1 strain circulating before 1957 and several lines of evidence show that older people exposed to that virus may have some immunity to the new H1N1.

The authors confirm that the new strain is comprised of segments from swine flu strains known to circulate in Europe, Asia and North America, but that this combination has not previously been seen and appears to have been evolving independently from its parent strains for some time.

They tested a strain of Zika virus currently circulating in human populations in the Americas and another from Africa, which is the original strain identified in 1947.

That's because there are multiple strains of flu viruses circulating at any one time, said Dr. William Schaffner, an infectious - disease specialist at Vanderbilt University Medical Center in Nashville.

«It was not known whether any of these vaccines could provide protection against the new outbreak West African Makona strain of Ebola Zaire currently circulating in Guinea,» said John Eldridge, Chief Scientific Officer - Vaccines at Profectus Biosciences, Inc. «Our findings show that our candidate vaccines provided complete, single dose protection from a lethal amount of the Makona strain of Ebola virus.»

The assay offers rapid, specific, sensitive, and inexpensive detection of the Asian - lineage Zika virus strain that is currently circulating in the Western hemisphere, and can also detect the African - lineage Zika virus strain using separate, specific primers.

«The matching process is not a perfect science, therefore, in some flu seasons, the vaccine available in the fall is not a good match for the circulating virus strains and is less effective,» said senior author David Weiner, Ph.D., Executive Vice President and Director of the Vaccine and Immune Therapy Center at The Wistar Institute.

Redinbo and his team now characterize various forms of Beta - glucuronidase produced by different strains of bacteria residing in the gut, and they show that inhibiting GI bacterial Beta - glucuronidases in mice does not affect irinotecan that is circulating in the blood and is needed to combat cancer.

A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide.

Writing in February in Vaccine, the researchers reported that the stored serum of elderly volunteers who received the vaccine in 2011 showed an immune response to new strains of flu that were circulating three years later.

In this case, researchers from the Icahn School of Medicine at Mount Sinai in New York City took tops from two flu strains that circulate only in birds, and connected each one to a human hemagglutinin stalk.

Those annual shots remain the best means of protection, but they must be manufactured months before flu season starts, based on a best educated guess of what strains of the virus will be circulating.

Various strains of H7N9 influenza have been circulating in China since 2013.

The researchers are taking hemagglutinin mutations from every flu strain that has ever circulated, dumping them into a kind of scientific blender and attaching them to particles that can form the basis of a vaccine.

Vaccine makers must anticipate months in advance which strains of flu will circulate each year.

Today's flu vaccines make the immune system produce antibodies that recognise structures on the surface of the virus to prevent infection with the most prevalent circulating strains.

In any given season, the effectiveness of the vaccine depends on how good a match there is between the viruses used in the drug's production and the strains that are actually circulating that year.

While only a few strains of flu virus circulate worldwide in a typical year, dozens more may exist.

So H1N1 in itself is a, you know, broad category of viruses that circulate in humans, even now; they are not as fearsome as the original strain when it first emerged.

Although the K13 C580Y strain is becoming dominant in parts of the region, the group said in a carefully worded report in March, that is not the case everywhere in the Greater Mekong, where several lineages are circulating more or less in equilibrium.

For the new study, researchers in Diamond's laboratory, led by first author Helen Lazear, PhD, now at the University of North Carolina at Chapel Hill, tested five strains of the Zika virus in the mice: the original strain acquired from Uganda in 1947; three strains that circulated in Senegal in the 1980s; and the French Polynesian strain, which caused infections in 2013 and is nearly identical to the strain causing the current outbreak.

He has long advocated global cooperation in the surveillance of circulating flu viruses to spot emerging new strains so public health officials could plan a response and drug companies could get a head start in making vaccines.

So it's a recombination of a number of sort of the North American strain that's been circulating for a long time, your Asian strain that we have not seen circulating in North America.

Strains of H3N2 have been circulating in humans since the 1968 pandemic, but they have evolved to a less dangerous form that produces a nasty seasonal flu.

«Most of what we know about Enterococcus comes from the few strains circulating in the hospital,» says Lebreton.

«The goal is to get a clearer picture of the strains that are circulating and therefore anticipate the right kind of a vaccine strategy for 2016,» Sasisekharan says.

The findings, which appear in the March 11 issue of Cell Host & Microbe, contradict previous reports from Indian health officials that the strain has not changed from the version of H1N1 that emerged in 2009 and has been circulating around the world ever since.

The strain of bacteria that has caused lethal food poisoning in Germany is carried by bean sprouts and may have been circulating in people for 10 years

The wild form of type 2 has been stamped out globally, but vaccine - derived forms of the strain still circulate in Nigeria and neighboring countries.

While this year's vaccine is a much better match to the circulating seasonal strains of influenza, the shifty nature of the virus and the need to pick the viruses used to make global vaccine stocks well before the onset of the flu season can make vaccine strain selection a shot in the dark.

Writing this week (May 23, 2016) in the journal Nature Microbiology, a team of researchers led by University of Wisconsin - Madison School of Veterinary Medicine virologist Yoshihiro Kawaoka describes a novel strategy to predict the antigenic evolution of circulating influenza viruses and give science the ability to more precisely anticipate seasonal flu strains.

ST. JULIAN»S, MALTA — The most aggressive of the circulating human flu strains is fast becoming resistant to a widely used class of flu drugs, researchers reported here last week at the Second European Influenza Conference.

What is more, the DNA in Haiti's cholera shows it was a single, recent introduction of a strain from south Asia, though we don't know if it is circulating in Nepal.

The study, published in the Journal of Infectious Diseases and funded by vaccine - maker Sanofi Pasteur, found that — with the exception of one strain of flu circulating in the 2012 - 2013 season — the high dose flu vaccine helped participants mount a better immune response to influenza than the standard flu shot.

Both the high - dose and standard flu vaccines contain inactivated versions of the three influenza strains that world health officials determine most likely to be circulating in a given flu season.

The strain likely resulted from a reshuffling of several avian influenza viruses circulating in domestic ducks and chickens, Guan's group reported in 2013.

As for H5N1, it may prove less deadly in humans than in birds because variants of H1N1, descendants of the 1918 flu, have been circulating again since 1977 in Southeast Asia, and exposure to that N1 - bearing strain may provide some protection.

It seems to have begun as a normal human flu strain that circulated in the United States in the spring of 1918.