Sentences with phrase «circulating tumor»

Greece Test Circulating Tumor Cells are cells that have been released from a tumor and are circulating in the blood stream.

The test detects so - called «circulating tumor cells» (CTCs).

Frouws» team believe the drug may boost the immune system's ability to detect and destroy circulating tumor cells in the blood.

The herringbone pattern of interior surfaces in the HB - Chip brings more circulating tumor cells into contact with the antibody - coated capture surfaces.

Immunicon Corporation (PI)($ 40,000 Total) 2001 - 2002 Longitudinal enumeration of circulating tumor cells in patients with metastatic breast carcinoma

One of these very exciting projects is barcoding of genes and their functional products in single cells of circulating tumor cells, CTCs», said Afshin Ahmadian.

We conducted a meta - analysis in nonmetastatic breast cancer patients treated by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (CTC) detection as a prognostic marker.

Blood - Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA.

Uncovers biomarkers and uses circulating tumor cells and circulating tumor - free DNA to predict responses to treatment

Our laboratory recently developed an interest in circulating tumor DNA (ctDNA), which may be used to determine the mutational landscape of a given tumor.

We have invented new biomaterial surfaces based on natural halloysite nanotubes, that capture rare circulating tumor cells (CTCs) from blood while simultaneously repelling white blood cells.

The clinical biostatistics team has strong connection with the Biometry department (Head A. Savignoni), the early phase clinical trial and precision medicine unit where patients are treated with drugs in development (Head C. Le Tourneau), the translational research department in particular the Circulating Tumor Biomarkers laboratory (Charlotte Proudhon), and of course the other teams of the U900.

Additionally, she is investigating the role of circulating tumor cells expressing these checkpoint molecules.

A technique already developed by Dr. Simeone's research team, in collaboration with Dr. Sunitha Nagrath, for isolating circulating tumor cells was the foundation for this novel approach to personalized therapeutics.

«People have been using circulating tumor DNA to try to make a few kinds of decisions — this is one of the first formal guidelines to endorse that use,» Aisner says.

Keywords: Metastasis, Circulating Tumor Cells, Intravasation, Epithelial - Mesenchymal - Transition, Angiogenesis.

On the plus side, Aisner points out, testing via circulating tumor DNA returns very few false - positives — when a test discovers DNA with a cancer - causing genetic change, it is strong evidence that this alteration is, in fact, present in the patient's cancer.

DENVER — Three manuscripts published in the recent issue of the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer (IASLC), explored the versatility of liquid biopsies by identifying EGFR mutations using circulating tumor DNA (ctDNA) in urine and plasma and examining circulating tumor cells (CTCs) in plasma to predict the risk of lung cancer recurrence after surgical resection.

Research Paper A dual biomarker detection platform for quantitating circulating tumor DNA (ctDNA) Chunyan Cai, Zhenzhong Guo, Yiping Cao, Weiying Zhang, Yong Chen Nanotheranostics 2018; 2 (1): 12 - 20.

The way in which they did this was by isolating circulating tumor cells from a drawing of blood.

Review Circulating Tumor Cells in the Parallel Invasion Model Supporting Early Metastasis Gerhard Hamilton, Barbara Rath Oncomedicine 2018; 3: 15 - 27.

Chi's presentation focused on first - line treatment outcomes and correlations with deep targeted sequencing of circulating tumor (ctDNA) that occurred at baseline.

UQ's Australian Institute for Bioengineering and Nanotechnology (AIBN) PhD student Jing Wang says the simple nanotechnology looked at changes in circulating tumor cells, which could indicate whether a cancer is attempting to spread and reveal its response to treatment.

Optical quantification of cellular mass, volume, and density of circulating tumor cells identified in an ovarian cancer patient.

Measurement of EGFR - mutant circulating tumor DNA (ctDNA) in the CSF showed that 7 of 9 patients had decreased ctDNA levels, with 5 patients having a > 50 % decrease.

The thrombotic potential of circulating tumor microemboli: computational modeling of circulating tumor cell - induced coagulation.

Quantification of cellular volume and sub-cellular density fluctuations: comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patient.

«Circulating tumor cells (CTCs) have been shed by the original tumor and entered the bloodstream — they can then form into new tumors if they lodge in distant tissue,» Wang says.

Levels of circulating tumor DNA (ctDNA) predicted worse outcomes including relapse and survival in patients with resected stage II / III melanoma, according to the results of a study published in Annals of Oncology.

In nonmetastatic triple - negative breast cancer (TNBC) patients, we investigated whether circulating tumor DNA (ctDNA) detection can reflect the tumor response to neoadjuvant chemotherapy (NCT) and detect minimal residual disease after surgery.

The technique, described in Biomaterials, uses gold nanoparticles and Raman scattering, a technology previously developed by Qian and Nie for cancer cell detection (2007 Nature Biotech paper, 2011 Cancer Research paper on circulating tumor cells).

The Berkeley researchers then analyzed each circulating tumor cell for the specific panel of cancer proteins.

The study focuses on circulating tumor cells, a potentially rich source of information about a person's cancer.

«Circulating tumor cells — cells from a tumor that have escaped into the bloodstream with the potential to spread into other tissues — are extremely useful for assessing a patient's disease in order to select the most appropriate treatment,» said UBC mechanical engineering professor Hongshen Ma, the lead researcher.

Once settled in the microwell, the circulating tumor cells were burst open and the proteins released from inside each cell were separated according to differences in size or mass.

Houston Methodist researchers led by Dario Marchetti, PhD, have developed a blood test that can identify circulating tumor cells to predict breast cancer patients at risk for developing brain metastasis.

To better study circulating tumor cells, the researchers collaborated with physician - scientists and industry engineers to develop a microfluidics system that separates these large cells into a concentrated sample.

So my field is science and technology, so my work is circulating tumor cells where I isolate cancer cells from blood of patients and isolate their DNA and RNA and try to sequence them and try to device treatments for cancer treatment and therapy.

Berkeley researchers isolated circulating tumor cells from the blood of breast cancer patients, then used microscale physics to design a precision test for protein biomarkers, which are indicators of cancer.

AR - V7 status was assessed through an experimental blood test that measures AR - V7 mRNA in circulating tumor cells.

A recent clinical study by Dr. Antonarakis and colleagues showed that mCRPC in men who had AR - V7 in circulating tumor cells was resistant to the hormone drugs enzalutamide and abiraterone.

The prognosis for metastatic cancer (also called stage IV cancer) is generally poor, so a technique that could detect these circulating tumor cells before they have a chance to form new colonies of tumors at distant sites could greatly increase a patient's survival odds.

«Our chip is currently the only device that can potentially capture circulating tumor cells and exosomes directly on the chip, which should increase its ability to detect metastasis.

This approach allows us to detect, with high confidence, changes in circulating tumor DNA across a large part of the genome without information from tumor tissue,» said Dr. Razavi.

While circulating tumor DNA tests targeting a smaller set of cancer genes are already available for use in routine practice to guide care, by covering a much larger number of cancer genes, this high - intensity sequencing approach may enable development of future tests for early detection of cancer.

The scientists used a highly innovative cell separation technology Parsortix ™, developed by UK company ANGLE plc that is able to capture the circulating tumor cells.

Circulating tumor DNA is a term used to describe the tiny pieces of genetic material that dying cancer cells shed into the blood circulation.

Researchers have found a group of circulating tumor cells in prostate cancer patient blood samples which are linked to the spread of the disease, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool.

The researchers used an enhanced version of a technique they developed called CAPP - Seq to isolate and sequence circulating tumor DNA, or ctDNA, from blood samples from the patients.

«Prior research in the field has primarily focused on using knowledge from tumor tissue sequencing to identify specific changes to look for in circulating tumor DNA.