Sentences with word «cirrhotic»
The word "cirrhotic" refers to a condition in which the liver is severely damaged and scarred. Full definition
The 12 - week combination of SOF / DCV / RBV achieved a 100 % SVR4 rate in cirrhotic patients without the additive effect of extension of the treatment to 24 weeks with or without RBV (95.7 % and 92.5 %, respectively), and this was also true in experienced patients.
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The study found that metformin reduced blood pressure in the liver, liver scarring and inflammation after one week of use in cirrhotic rats.
Phase III results revealed today at The International Liver Congress ™ 2015 show that once - daily treatment with daclatasvir (DCV) plus sofosbuvir (SOF) resulted in an overall 97 % sustained virologic response (SVR) at 12 weeks post-treatment in patients with hepatitis C virus (HCV) and HIV co-infection, including cirrhotic patients.
If liver disease is treated before becoming cirrhotic (enters the cirrhosis phase), enough liver tissue may be regenerated to allow the liver to function normally.
Long - term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients.
«We are pleased to see the efficacy of this two direct - acting antiviral investigational, pan-genotypic regimen has been validated for treatment - naïve Hepatitis C genotype 3 patients — with 100 % of cirrhotic patients treated for 12 weeks and 97 % of non-cirrhotic patients treated for eight weeks achieving sustained virologic response at 12 weeks post treatment,» said Dr Paul Kwo from Indiana University School of Medicine, Indianapolis, US and one of the lead study authors.
In addition, they found that cirrhotic human livers had much greater numbers of the NOX1 and NOX4 proteins than normal livers.
It isn't just that he has great pipes and can sing the hell out of Foley's tunes (his rendition of «If I Could Only Fly» is heartbreaking); more importantly, Dickey knows how to give this bearded bear of a man both what - me - worry charm and sodden melancholy, the kind that says volumes about the man who made that music — his Foley is equal parts heart, soul and cirrhotic liver.
The article «Metformin reduces hepatic resistance and portal pressure in cirrhotic rats» is published ahead - of - print in American Journal of Physiology — Gastrointestinal and Liver Physiology.
The results show that 12 weeks of DCV - SOF is a highly effective and well - tolerated treatment regimen for HCV in patients with HIV co-infection, including cirrhotic patients.
Also, eggs (poached / soft - boiled) Low cholesterol dries out the liver and it will become cirrhotic.
Long term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need, and malondialdehyde levels in cirrhotic diabetic patients.
Treatment of acute hepatic encephalopathy in cirrhotics with a branched - chain amino acids enriched versus a conventional amino acids mixture.
Morgan, M. Y., Hawley, K. E., and Stambuk, D. Amino acid tolerance in cirrhotic patients following oral protein and amino acid loads.
However, treatment - experienced genotype 3 cirrhotic patients experienced a lower SVR rate of 60 %.2
In the international Phase 2 clinical trial, two study arms enrolled 24 cirrhotic patients each, none who had previously been treated for HCV infection.
In the total patient population, the 5 - year overall survival rate was 95 %, although it was significantly higher in non-cirrhotic (97 %) than cirrhotic patients (92 %).
We also found that the combination with ribavirin increases the SVR rate in cirrhotic or experienced patients without the additive effect of the extension of the treatment from 12 to 24 weeks.
Scientist at the University of Bonn and TU Munich have now discovered that type I IFN released by immune cells due to increased migration of gut bacteria into the cirrhotic liver incapacitate the immune system.
Preconditioning with death ligands FasL and TNF - alpha protects the cirrhotic mouse liver against ischaemic injury.
Taking advantage of infected patients, proprietary animal models of infection and new technological advances in the field of static and dynamic imaging, Immunopathology Unit tackles unresolved issues that include the means by which innate and adaptive immune cells traffic and function within the normal, cirrhotic or cancerous livers.
Hepatic encephalopathy verified by psychometric testing and EEG in cirrhotic patients: Effects of mesocaval interposition shunt or sclerotherapy..
Vegetable versus animal protein diet in cirrhotic patients with chronic encephalopathy.