Sentences with phrase «cirrhotic liver»

It isn't just that he has great pipes and can sing the hell out of Foley's tunes (his rendition of «If I Could Only Fly» is heartbreaking); more importantly, Dickey knows how to give this bearded bear of a man both what - me - worry charm and sodden melancholy, the kind that says volumes about the man who made that music — his Foley is equal parts heart, soul and cirrhotic liver.

I heard a cirrhotic liver, a liver that's not functioning well, it's really only a 10 % difference in its function.

Scientist at the University of Bonn and TU Munich have now discovered that type I IFN released by immune cells due to increased migration of gut bacteria into the cirrhotic liver incapacitate the immune system.

Not exact matches

The study found that metformin reduced blood pressure in the liver, liver scarring and inflammation after one week of use in cirrhotic rats.

The article «Metformin reduces hepatic resistance and portal pressure in cirrhotic rats» is published ahead - of - print in American Journal of Physiology — Gastrointestinal and Liver Physiology.

In addition, they found that cirrhotic human livers had much greater numbers of the NOX1 and NOX4 proteins than normal livers.

Hepatic encephalopathy occurs when the liver can not remove certain toxins and chemicals, such as ammonia, from the blood.1 These toxins and chemicals then build up and enter the brain.1 Hepatic encephalopathy is one of the major complications of cirrhosis (scarring of the liver), and a leading cause of hospital re-admission due to its recurrence, despite treatment.1 It can occur suddenly in people with acute liver failure, but is seen more often in those with chronic liver disease.1 Symptoms of hepatic encephalopathy include mild confusion, forgetfulness, poor concentration and personality or mood changes, but can progress to extreme anxiety, seizures, severe confusion, jumbled and slurred speech and slow movement.1 The first step in treatment is to identify and treat any factors that cause hepatic encephalopathy.2 Once the episode has resolved, further treatment aims to reduce the production and absorption of toxins, such as ammonia.1 Generally, there are two types of medication used to reduce the likelihood of another hepatic encephalopathy episode — lactulose and rifaximin.2 However, it remains a leading cause of hospitalisations and re-hospitalisations in cirrhotic patients, despite the use of the above - mentioned standard of care treatment.

Liver cirrhosis is a leading cause of morbidity and mortality, with complications such as HE resulting in recurrent emergency hospitalizations, irreversible brain injury, and a poor prognosis.2 - 5 There is some evidence that HE patients have a reduced relative abundance of certain beneficial gut microbiota (e.g. Lachnospiraceae and Ruminococcaceae) and an enrichment of potentially pathogenic Enterobacteriaceae ¬ - a microbial profile that has been linked to cognitive impairment and systemic inflammation in cirrhotic patients with HE.1 Faecal microbiota transplants have been used successfully to correct dysbiotic conditions such as recurrent Clostridium difficile and ulcerative colitis,6 - 8 and a preliminary report suggested that FMT may be promising in the management of HE.9

Taking advantage of infected patients, proprietary animal models of infection and new technological advances in the field of static and dynamic imaging, Immunopathology Unit tackles unresolved issues that include the means by which innate and adaptive immune cells traffic and function within the normal, cirrhotic or cancerous livers.