This is a relatively new
class of drugs also including Farxiga, Jardiance, Glyxambi, and Xigduo XR.
Not exact matches
A pharmacologist by training, I
also knew that the bisphosphonates — a
class of drugs developed for osteoporosis sufferers — were then being tested on OI patients.
The Cabinet Office minister and Tory policy architect had
also dismissed proposals to foster a new
class of black entrepreneurs, saying they would simply set up in the «disco and
drug trade».
The report
also recommended the re-classification
of cannabis to a
class C
drug.
-- The budget would
also allow the state's health commissioner to negotiate rebates directly with pharmaceutical companies for certain kinds
of drugs, including HIV / AIDS
drugs and Hepatitis C
drug classes.
Across the aisle, Assemblyman Billy Jones (D - Chateaugay), who took office earlier this month, said he liked the middle
class tax cut and increased education aid, and
also hailed the governor's proposals to build on fighting the opiate epidemic, including the creation
of drug recovery «high schools» and crisis treatment centers alongside deeper insurance reforms.
(GlaxoSmithKline has decided to stop marketing ezogabine but other existing
drugs that
also operate by tweaking potassium channels in brain cells — or a wholly new
class of compounds — could serve in its place.)
The researchers, however,
also found that it may be possible to mitigate these effects with the use
of an experimental
class of drugs that can block stress.
They have
also made antimicrobial peptides, which scientists are exploring as a possible new
class of antibiotic
drugs.
For some years now, a new
class of drugs called antibody -
drug conjugates (ADCs) have been used, which work in two ways: they consist
of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they
also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.
Various companies are
also testing a
class of drugs that target both IGF - 1R and the insulin receptor.
The rationale for using spironolactone - an inexpensive, generic, medication - stems from the pioneering research
of Bertram Pitt, MD, University
of Michigan School
of Medicine, who showed the benefit
of this
class of drugs in patients with heart failure and reduced ejection fraction, and who
also served as chair
of the TOPCAT Steering Committee.
Much like BMS, Celgene
also made a big gamble about a decade ago when it developed a
class of immune - modulating
drugs that included the infamous teratogen thalidomide.
The agency was
also called to testify before Congress about its inaction regarding side effects
of the antibiotic Ketek and a widely used
class of anemia
drugs.
The determination
of each efficacy level was
also based on the rigor and quantity
of published studies on the
drug class: to be in Level A, for example, a class of drugs must have been supported by at least two «Class I» studies — well - designed, double - blind, randomized, placebo - controlled clinical tr
class: to be in Level A, for example, a
class of drugs must have been supported by at least two «Class I» studies — well - designed, double - blind, randomized, placebo - controlled clinical tr
class of drugs must have been supported by at least two «
Class I» studies — well - designed, double - blind, randomized, placebo - controlled clinical tr
Class I» studies — well - designed, double - blind, randomized, placebo - controlled clinical trials.
Ledipasvir belongs to a promising new
class of DAA
drugs that work by blocking the NS5A protein, which the hepatitis C virus
also needs to replicate.
He notes, however, that in the wake
of the criminalization
of first - generation cathinone derivatives, new members
of this
drug class are being invented that will
also require study.
Sirolimus belongs to the rapamycin
class of drugs that
also includes everolimus.
Vitamin B6 has been shown to have a small effect on hangover in scientific studies, as have prostaglandin inhibitors, a
class of drugs that includes aspirin and ibuprofen; for optimum effectiveness these should be taken while you are drinking, not the next morning, though they can
also help the morning after.
There are already three
classes of antiobesity
drugs: adrenergic agents, which boost catecholamine levels to reduce appetite and enhance the sensation
of being full; a combination adrenergic and serotonergic system that
also inhibits serotonin reuptake; and lipase binders, which inhibit the body's ability to absorb fat.
A new
class of biologic
drugs came onto the market in Canada last year, and while more effective for treating high - cholesterol, they are
also more expensive.
The resulting «map»
of gene -
drug interactions allowed the researchers to accurately predict the responses
of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and
also revealed new genetic factors that appear to determine the response
of breast and ovarian tumor cells to common
classes of chemotherapy treatment.
Monk
also said that Gpr56 belongs to a large
class of cell receptors that are common targets for many commercially available
drugs, making the protein attractive for further research.
Less than a decade after a powerful gene - silencing method — RNA interference, or just RNAi — was discovered, the field's pioneers have not only won the 2006 Nobel Prize in Physiology or Medicine but have
also helped launch an entirely new
class of drugs into human clinical trials.
It
also showed that the public cost
of expanding public coverage for high - cost
drugs — such as treatments for cancer and rheumatoid arthritis — would be modest and, under most plausible scenarios, would be offset by savings achieved in relatively common
drug classes — like treatments for high cholesterol and high blood pressure.
Medical options
also have improved substantially, with the availability in recent years
of new
classes of diabetes
drugs such as GLP - 1 (glucagon - like peptide - 1) receptor agonists and SGLT2 (sodium - glucose co-transporter-2) inhibitors.
More recently, strains
of tuberculosis have emerged that are resistant not only to front - line antibiotics, but
also to one or more
drugs within each
of the two most important
classes of second - line
drugs — broad - spectrum antibiotics called fluoroquinolones, and injectable agents (amikacin, capreomycin and kanamycin).
In the paper, the researchers
also described that single - cell phosphoproteomics could be used to study how melanoma cells develop resistance to a
class of drugs called BRAF inhibitors.
Focusing on gastric cancer (GC), the third leading cause
of cancer death worldwide, the team's findings may
also prove applicable to other major cancers with potential implications for how cancers might be better treated with immunotherapy, one
of the most promising
classes of anti-cancer
drugs today.
Tu
also received numerous awards nationally which include «Award for Progress in Anti-malarial Research Achieved by Project 523 Scientific Team» honored by China National Congress
of Science and Technology (1978); «National Scientific Discovery Award» for Anti-malaria
Drug - Qinghaosu by the China Ministry
of Science and Technology (1979); «Invention Award» (as the first inventor) by China National Congress for Awards in Science and Technology (1982); «Award
of Young and Middle - aged Experts with Outstanding Contribution» by the Chinese Government (1984); «The Top Honorary Award» by China Academy
of Traditional Chinese Medicine (1992); «The Top Ten National Achievements for Progress in Science and Technology» by China National Committee
of Science and Technology (1992); «First -
Class Award
of National Achievements in Science and Technology» by China National Award Committee for Advances in Science and Technology (1992); «National Model» by China State Council (1995); «Award for Outstanding Achievement in Traditional Chinese Medicine» by Guangzhou Zhongjing Award Foundation for Traditional Chinese Medicine (1995); «Outstanding Scientific Achievement Award» by Qiu Shi Science and Technologies Foundation
of Hong Kong (1996); «Top Ten Health Achievements in New China» by China Ministry
of Health (1997); «Female Inventor
of the New Century» by China National Bureau
of Intellectual Property (2002); «Golden Medal
of the 14th National Invention Exhibition» by China National Bureau
of Intellectual Property (2003); «Award for Development
of Chinese Materia Medica» by Cyrus Chung Ying Tang Foundation, (2009).
PULLMAN, Wash. — A
class of drugs used to treat parasitic infections such as malaria may
also be useful in treating cancers and immune - related diseases, a new WSU - led study has found.
The discovery builds on research showing that a promising
class of new
drugs for BRCA2 linked breast cancers — known as PARP inhibitors ** — may
also be effective in men who have developed prostate cancer due to a BRCA2 alteration.
Concerns have been raised about the safety
of antipsychotics, but concomitant use
of multiple psychotropic
drug classes (psychotropic polypharmacy) may
also pose a risk for patients.
Furthermore, he demonstrated that a
class of drugs often used in the treatment
of diabetes
also reduces the harmful effects
of white fat cells on bones.
(Tuesday, March 21, 2017 - Toronto)- A pilot study
of a
class of drugs used to treat hepatitis and some forms
of multiple sclerosis has been shown for the first time to ease symptoms
of Ebola patients, while
also increasing their survival.
The study
also showed that, in contrast to several cancer
drugs that have been documented to cause cardiac toxicity, BRD4 inhibitors may be a
class of anti-cancer therapeutics that has protective effects in the human heart.
eFFECTOR is pioneering a new
class of small molecule
drugs that act by selectively regulating translation,
also known as protein synthesis.
This
class of medications
also includes older antihistamines like chlorpheniramine (Chlor - Trimeton) and «antimuscarinic»
drugs for bladder control, such as oxybutynin (Ditropan).
«We should look
also at older
drugs that may have been discarded, and perhaps work more to understand the mechanism
of action
of acetaminophen to develop a new, more effective and less toxic
drug of the same
class, or develop new
classes of painkillers,» Moore suggested.
Hot flashes are common with AIs, a
class of drugs that
also includes Aromasin and Femara and that women generally stay on for up to five years.
«This is going to open up a new opportunity for patients, and
also for further research,» said Dr. Edith Perez, chairwoman
of the breast cancer clinic at the Mayo Clinic in Jacksonville, Fla. «It has some limitations in that it was done only in premenopausal women, but it is consistent with other studies that have been reported with other
drugs in that same
class.»
A darkly comic indictment
of Britain's upper
class, Patrick Melrose, which
also stars Jennifer Jason Leigh and Blythe Danner, follows its protagonist from age five, when he is abused by his father (played by Hugo Weaving) in a country house in Provence, through his young adulthood, when he becomes a heroin addict in New York and London, to his recovery from
drugs and transition to fatherhood.
Bigger Than Life (Criterion) Ostensibly a drama about prescription
drug misuse and abuse and drawn from an article in The New Yorker, this portrait
of a grade - school teacher and middle
class father (played by James Mason, who
also produced and helped develop the project) is as much about adult male masculinity and responsibility as a husband and father, and the pressure on him to live up to the ideal, as Rebel Without a Cause is about the emotional realities
of being an American teenager.
But it is
also a remarkably nuanced novel whose currents run much deeper, delving into the minds
of four characters: Aguilar, a husband passionately in love with his wife and determined to rescue her from insanity: Agustina, a beautiful woman from an upper -
class Colombian family who is caught in the throes
of madness; Midas, a
drug - trafficker and money - launderer, who is Agustina's former lover; and Nicolás, Agustina's grandfather.
Benazepril, a blood pressure medication belonging to a
class of drugs known as ACE inhibitors, may
also be given to dogs with kidney disease, as it helps with kidney failure and conditions where excess protein is being excreted through the dog's kidneys into the urine.
Veterinarians have
also used other prescription
drugs of this
class, including Tramadol and Torbutrol to manage pain in cats.
Mario
also represents individuals on the civil side in the following types
of cases:
class actions, social security disability, workers compensation, personal injury including traumatic injury, defective products including defective
drugs, nursing home neglect, and predatory lending.
A PSNI spokesman
also revealed that the search was «in connection with the arrest
of a 30 - year - old man in the Ladybrook area
of west Belfast on suspicion
of possession
of Class A
drugs»,
also on Wednesday.