Sentences with phrase «class of drugs into»

18 Drugs Aim to Silence Bad Genes RNA interference helped launch an entirely new class of drugs into trials...

Less than a decade after a powerful gene - silencing method — RNA interference, or just RNAi — was discovered, the field's pioneers have not only won the 2006 Nobel Prize in Physiology or Medicine but have also helped launch an entirely new class of drugs into human clinical trials.

Not exact matches

It is assessed that this network of OCGs will continue to supply large volumes of class A drugs into the UK,» the spokeswoman added.

Biotech giant Gilead Sciences is beefing up its cancer drug portfolio with a $ 11.9 billion deal to buy Kite Pharma, a company focused on a groundbreaking new class of treatments that turns the body's own immune cells into targeted blood cancer killers.

Preliminary results of the study were presented at a World Health Organization (WHO) evidence review group meeting, while UNITAID has issued a call for further research into the use of endectocide class drugs, of which ivermectin is currently the only one registered for human use, as new vector control tools in the fight against malaria and other mosquito borne disease.

In 2009, BMS took a big risk jumping into the immunotherapy field by acquiring the company Medarex, which brought with it Yervoy, a member of a new class of cancer drugs.

The research on advanced anaerobic digestion examined a popular class of antibiotics called tetracyclines, finding that these drugs and their breakdown products migrated from the fluid part of the sludge into the solid part during treatment.

The findings make evacetrapib the third failure in a class of drugs known as cholesteryl ester transfer protein (CETP) inhibitors, which are designed to disrupt the natural process by which HDL cholesterol is converted into LDL cholesterol in the body.

«This new class of immunotherapy drug traps white blood cells in the lymph nodes to prevent their escape into the gut where they cause inflammation,» said William J. Sandborn, MD, professor of medicine at UC San Diego School of Medicine and director of the Inflammatory Bowel Disease Center at UC San Diego Health.

The most notorious example of this class is HIV proteinase, commonly called HIV protease, which helps the virus cut a long polypeptide into functional proteins; it has become the target of several successful AIDS drugs.

Taking that concept into biomedical research has yielded a breakthrough: This past May the mTOR inhibitor everolimus was approved by the U.S. Food and Drug Administration for the treatment of advanced pNET, the first drug in this class approved for this diseDrug Administration for the treatment of advanced pNET, the first drug in this class approved for this disedrug in this class approved for this disease.

A class of oral specialty drugs, tyrosine kinase inhibitors (TKIs), has revolutionized the treatment of CML, largely transforming it into a chronic condition and enabling many patients to have a near - normal lifespan, particularly when compared to a median survival of less than three years with prior therapies.

In their recent study, the UCSF team reports the discovery that a class of commonly prescribed Type - 2 diabetes drugs, called TZDs (thiazolidinediones, such as Actos and Avandia), promoted the conversion of white fat cells into brown (in mice and culture dishes) by stabilizing the PRDM16 protein.

To make a monoclonal antibody — a class of biologic drug that, while perhaps not as well known as the influenza vaccine or insulin (two other kinds of biologics), is highly prevalent — scientists start by inserting a gene into a cell that will enable it to produce a desired protein.

Precisely where these findings will lead drug treatment strategies is unclear, but this work provides insight into the role of nicotinic receptors in the vulnerability to multiple classes of addictive drugs.»

4/7/2008 From Bench to Bedside in One Year: Stem Cell Research Leads to Potential New Therapy for Rare Blood Disorder A unique partnership between industry and academia has led to human clinical trials of a new drug for a rare class of blood diseases called myeloproliferative disorders (MPD), which are all driven by the same genetic mutation and can evolve into leuk... More...

Resources poured into the development of new classes of drugs.

By - the - books Starsky has issues with Hutch's loose cannon personality, but they begin to form a workable friendship as they track down a high - class drug dealer (Vince Vaughn) who has just introduced an undetectable form of cocaine into the market.

But it is also a remarkably nuanced novel whose currents run much deeper, delving into the minds of four characters: Aguilar, a husband passionately in love with his wife and determined to rescue her from insanity: Agustina, a beautiful woman from an upper - class Colombian family who is caught in the throes of madness; Midas, a drug - trafficker and money - launderer, who is Agustina's former lover; and Nicolás, Agustina's grandfather.

Benazepril, a blood pressure medication belonging to a class of drugs known as ACE inhibitors, may also be given to dogs with kidney disease, as it helps with kidney failure and conditions where excess protein is being excreted through the dog's kidneys into the urine.

The nation's gamble in embracing new drugs for long - term use with only short - term clinical testing was most apparent in the rapid acceptance into clinical practice of a new class of oral diabetes drugs called sodium - glucose cotransporter - 2 (SGLT2) inhibitors.

The classes are taught in a typical classroom setting and taken to a clinical lab setting to practice accurate drug caluculations, measuring and drawing up liquid medications into a syringe, and practicing injection techniquies under the watchful eye of an experienced medical assistant instructor.