Sentences with phrase «class of drugs known»

Invokana is in a class of drugs known as sodium - glucose cotransporter 2 (SGLT2) inhibitors.

Ciprofloxacin (Cipro) belongs to a class of drugs known as fluoroquinolones, which are one of the most commonly prescribed classes of antibacterial drugs.

Manufactured by Johnson & Johnson, Invokana belongs to a class of drugs known as sodium - glucose co-transporter 2 (SGLT2) inhibitors.

Ovaban works via a different mechanism than Cheque Drops, and is part of a class of drugs known as progestins.

Interestingly though, a class of drugs known as tricyclic antidepressants (TCA) helps slow down the reabsorption rate of the neurotransmitters serotonin and norepinephrine allowing their levels to rise.

Benazepril, a blood pressure medication belonging to a class of drugs known as ACE inhibitors, may also be given to dogs with kidney disease, as it helps with kidney failure and conditions where excess protein is being excreted through the dog's kidneys into the urine.

Prednisone belongs to a class of drugs known as corticosteroids.

Deguelin belongs to a class of drugs known as mitochondrial inhibitors.

That produced a class of drugs known as angiotensin - converting enzyme, or ACE, inhibitors that hit the market in the early 1980s, and during the next 25 years or so, there followed a string of blockbuster small - molecule drugs that included such familiar names as Lipitor, Zantac and Prozac.

Paclitaxel, the first of a class of drugs known as taxanes, is approved by the FDA for the treatment of advanced ovarian cancer.

PD -1-blocking agents such as nivolumab, pembrolizumab and atezolizumab are part of a class of drugs known as checkpoint inhibitors, and many cancer researchers are now trying to figure out how to enhance their activity by combining them with other types of drugs.

A class of drugs known as mTOR inhibitors blocks that pathway.

Lansoprazole belongs to a class of drugs known as «proton - pump inhibitors» that keep the stomach from pumping too much acid, thus preventing heartburn and ulcers.

However a new class of drugs known as «immunocheckpoint regulators» have shown huge potential, Soria says.

The findings make evacetrapib the third failure in a class of drugs known as cholesteryl ester transfer protein (CETP) inhibitors, which are designed to disrupt the natural process by which HDL cholesterol is converted into LDL cholesterol in the body.

Dinaciclib is a member of a class of drugs known as cyclin - dependent kinase (CDK) inhibitors.

Bazedoxifene is a pill that, like tamoxifen, belongs to a class of drugs known as specific estrogen receptor modulators (SERMs).

Preventative treatment of malaria is a useful strategy to protect young children in Africa, but it is unclear which drug and dosing strategy is most effective, especially with the rise of resistance to a class of drug known as antifolates, such as sulfadoxine - pyrimethamine (SP) and trimethoprim - sulfamethoxozole (TS).

Not exact matches

A pharmacologist by training, I also knew that the bisphosphonates — a class of drugs developed for osteoporosis sufferers — were then being tested on OI patients.

«I don't know if I've ever been more excited about a class of drug than I am about [mRNA],» Whitehead says.

The studies focused on motor behavior, not mood disorders, but the team found that certain classes of psychotropic drugs, such as the antidepressants known as monoamine oxidase inhibitors, had recognizable, characteristic effects on behavior.

3BP, part of a class of compounds known as small molecule drugs, was first studied as an anti-cancer agent more than a decade ago at Johns Hopkins by biochemists Young Hee Ko and Peter Pedersen, together with radiologist Jeff Geschwind.

One class of immunotherapeutic drugs is known as «checkpoint» inhibitors, as they target checkpoints in immune system regulation to allow the body's natural defenses, such as white blood cells, to more effectively target the cancer.

Nivolumab is part of a class of immunotherapy drugs known as PD - 1 blocking antibodies.

The result has been the emergence of strains of infections including tuberculosis and malaria, pneumonia and gonorrhoea that resist all known classes of drugs.

Initial treatment for most multiple myeloma patients includes a class of drugs (Revlimid or Pomalyst) broadly known as immune modulators.

A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life - threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.

Known as a COX - 2 inhibitor, Bextra belongs to the same class of drugs as rofecoxib (Vioxx), which manufacturer Merck yanked from pharmacy shelves last September after safety risks appeared (SN: 10/30/04, p. 286: Available to subscribers at COX - 2 inhibitor pulled off market.).

To make a monoclonal antibody — a class of biologic drug that, while perhaps not as well known as the influenza vaccine or insulin (two other kinds of biologics), is highly prevalent — scientists start by inserting a gene into a cell that will enable it to produce a desired protein.

Ten years later, Ashworth identified a way to exploit genetic weaknesses in cancer cells that include mutated BRCA2, which led to the development of a successful new class of cancer drugs known as PARP inhibitors.

Embedded within MD Anderson's culture of innovative academic science and clinical excellence, the institute aligns drug discovery and development research directly with the world - class science and clinical care for which MD Anderson is known.

Recent cancer treatments take advantage of this knowledge with a class of drugs that block protein degradation, known as proteasome inhibitors.

The discovery builds on research showing that a promising class of new drugs for BRCA2 linked breast cancers — known as PARP inhibitors ** — may also be effective in men who have developed prostate cancer due to a BRCA2 alteration.

Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting

The drug, manufactured by Amgen, is the first of a novel class of agents known as bispecific T cell engagers (BiTE), which consist of essentially two monoclonal antibodies joined together.

eFFECTOR is pioneering a new class of small molecule drugs that act by selectively regulating translation, also known as protein synthesis.

The best - known class of drugs for curbing heartburn are the antacids — , think Tums, Rolaids, and Mylanta.

The most commonly used drugs are a class of sedatives known as benzodiazepines (BZs).

This complex synthesis involves 37 steps and starts with a key enzyme known as HMG - CoA reductase (inhibited by statins, a class of cholesterol - lowering drugs).

SARMs or otherwise known as Selective Androgen Receptor Modulators, are a class of drugs intended...

SARMs or otherwise known as Selective Androgen Receptor Modulators, are a class of drugs intended to offer anabolic benefits seen in traditional steroids.

The new findings «just further substantiate what we know about this class of drugs,» says Charles Loprinzi, MD, a professor of oncology at the Mayo Clinic, in Rochester, Minn..

Being a part of the class of drugs that inhibit the action of a family of enzymes known as the Janus Kinases or JAKs, JAK Inhibitors effectively block the signals generated by various cytokines.

Phenobarb (as it is known) is a member of the barbiturate class of drugs, but given orally is as safe in IG's as in any other breed.

Unlike many earlier drugs of its class including aspirin, and other prescription NSAIDs, Deramaxx functions in blocking what are known as Cox 2 enzymes.

Here's something else to consider (and worthy of a massive class action lawsuit): the water and sewer systems they «require» you to hook up to are providing you with water contaminated with hundreds of pharmaceuticals; you have no way of knowing what peed - out drugs are still in your water supply because although «they» know it's there, they won't tell you for fear you might object.

On top of that, they should know the area of law that is involved in your class action (e.g. consumer fraud, contract law, drugs, etc.) and demonstrate a successful record handling similar cases.

Invokana (canagliflozin) was the first drug of a new class of diabetes drugs known as sodium - glucose cotransporter - 2 (SGLT2) inhibitors.

While it would be nice to think you could read headlines like, «New Drug Cure Hepatitis C Completely», and know that the next headline coming would be, «Life Insurance Companies Give Best Rate Class To Those Cured Of Hep C», don't hold your breath.

As a doctor, you need to know about medications and how much of a bonus would it be to already know the drugs and classes.