Sentences with phrase «class of protein encoding»

Not exact matches

Study of genes encoding the molecules of the malaria parasite's outer coat reveals a class of proteins forming repeated antigenic sites.

These therapies, the first an antibody and the second of a class called tyrosine kinase inhibitors (TKIs), reduce the ability of a target gene to manufacture the protein it encodes.

The genes involved encode proteins that control the activity of a very important and ubiquitous class of molecules that are a major target of pharmacologic agents across medicine,» says Ethan Goldberg, MD, PhD, an attending physician and instructor of neurology at the Children's Hospital of Philadelphia and The Perelman School of Medicine at The University of Pennsylvania.

Although antimicrobial peptides are not the only functional class to be overrepresented among short, secreted proteins encoded by members of multi-gene families, the prevalence of these properties among induced genes strongly suggests the possibly that at least some of these genes encode novel immune effectors.

While none of the genes encoding signaling proteins have evidence for differential expression after infection, this functional class is notable for the consistency with which we can detect expression in both uninfected and infected samples.

In the present study, we have used the proteins encoded by the most probabilistic sequences at six Precambrian phylogenetic nodes in the evolution of class A β - lactamases (Fig. 1).

He was a principal investigator of an ENCODE grant to devise strategies to map the binding of certain proteins to the human genome and to develop novel experimental approaches to examine specific classes of regulatory elements.

Genetically encoded biosensors are a class of GFP - based probes that report on protein activities, posttranslational modifications, conformational changes or other molecular processes.