Sentences with phrase «class of proteins»

Inside plant cells, ABA does its job by turning on a special class of proteins called receptors.

There are several new classes of proteins found in grain.

Called «pulses,» this unique class of protein - rich carbs includes lentils, chickpeas, and many varieties of beans.

Circumventing a long - standing problem in drug design, scientists have developed a novel way to identify a new class of protein building blocks that could serve as valuable leads for drug development...

In 2015, the team received a National Science Foundation Early Concept Grant for Exploratory Research (EAGER) award to investigate a newly discovered class of proteins that are turned on by heat.

In humans and other animals, RNA editing creates diversity in certain classes of proteins encoded by the nuclear genome.

CARM 1 promotes nuclear export of special class of RNAs (3/15/15) Assistant Professor Donghang Cheng, Ph.D. in Dr. Mark Bedford's group was the co-corresponding author on a study demonstrating that in the absence of the arginine methyltransferase CARM1, a certain class of protein encoding RNAs remain in the nucleus.

This new class of protein compounds that are easy to produce and have a large number of favorable binding properties was also invented and created in Plückthun's biochemistry lab.

It provides the first experimental backing for a hypothesis, called spectral proximity, which holds that the degree of color blindness depends on the characteristics of the remaining photoreceptors — in particular, whether there is sufficient gap in the wavelengths detected by the remaining pigment to compensate for the absence of the third class of proteins.

«Further, our work represents a milestone in designing and understanding membrane proteins, a particularly challenging class of proteins.»

A cytosolic yeast karyopherin, Kap104p, was isolated and shown to function in the nuclear import of a specific class of proteins.

Normally luminal cells are «programmed» by a particular class of proteins (transcription factors), which prevent them from becoming basal cells, and vice-versa.

Rather, these neurons express the MS4A class of proteins, which were previously not known to play a role in odor perception.

«KSR belongs to a large class of proteins that are not only implicated in the development of cancer, but also other diseases as well,» Dr. Dar explained.

Prions are a special class of protein that can change the shape and function of other proteins around them.

An entire class of proteins called transcription factors, which regulate the activity of certain genes by interacting with specific sequences of DNA, has largely been ignored by the pharmaceutical industry because it's difficult to design and screen drugs against them.

Perform an experiment that demonstrates how we can harness the catalytic power of a hard - working class of proteins called enzymes in industry.

«Wheat contains several different classes of proteins.

Cross reactivity refers to a reaction that occurs when people allergic to one class of proteins react to another similar in structure.

In the late 1990s — with the advent of a new class of protein - based drugs, monoclonal antibodies — demand sometimes outstripped supply.

As the title clearly states, this class of protein powder is vegan — meaning that it is totally devoid of animal products.

«Understanding the fundamental properties of this class of proteins is very relevant,» said Elizabeth Gavis, the Damon B. Pfeiffer Professor in the Life Sciences and a professor of molecular biology.

The technology tracks a class of proteins called membrane proteins as they interact with other proteins to either maintain health or contribute to disease.

Aiolos is a member of a class of proteins called transcription factors — proteins that control which genes are turned on or off by binding to DNA and other proteins.

Allen previously discovered a class of proteins secreted by astrocytes that help neurons form active connections, known as synapses.

In the early 1990s, Guarente discovered that sirtuins, a class of proteins found in nearly all animals, protect against the effects of aging in yeast.

Ovaa and Neefjes» team decided to look at another class of proteins, called phosphatases, that act in the opposite way from kinases to see if inhibiting them would have a similar effect.

Six years ago, Tanzi and neuroscientist Robert Moir, also at MGH, decided to test a hunch that ß amyloid behaves similarly to a class of proteins with well - known beneficial properties, called antimicrobial peptides, or AMPs.

«Successful efforts to render transcription factors «drugable» by interfering with different aspects of their transcriptional activity make this class of proteins attractive targets for therapy,» says Dr. Cohen - Solal, a researcher at the Cancer Institute and an assistant professor of medicine at Rutgers Robert Wood Johnson Medical School.

Abnormal and uncontrolled production of this class of proteins, known as transcription factors, allow for cells to bypass growth control mechanisms and to develop characteristics necessary for invading surrounding tissues.

The team of international scientists had discovered that by activating Nurr1, a class of proteins found in the brain, it protects the brain's ability to generate dopamine neurons.

Cry4 is part of a class of proteins called cryptochromes, which are known to be involved in circadian rhythms, or biological sleep cycles (SN: 10/02/17, p. 6).

The problem chiefly involves antibodies, a class of proteins scientists have used for generations for everything from quantifying receptor expression to purifying critical gene products.

To find out, she and her MIT colleagues targeted a class of proteins called TRPV1 channels, which are found in neurons that respond to heat and certain chemicals in food.

Clegg suspects that a class of proteins called molecular chaperones, which protect other proteins from degrading, may be responsible for the shrimps» impressive resilience.

«The longer we study these classes of proteins, the clearer it becomes how adept these molecules are at interfering with cellular growth to such an extent that makes normal control virtually impossible,» says Prof. Slany.

Study of genes encoding the molecules of the malaria parasite's outer coat reveals a class of proteins forming repeated antigenic sites.

Survivin belongs to a class of proteins that prevent cells from self - destructing, a process known as apoptosis.

Dr. Yang's team has developed the new class of protein - based contrast agents and tested one called ProCA32 that enabled a much earlier detection of liver cancer tumors in mice.

A study in France in 2004 investigated the impact of various doses of DDT and three other pesticides from the same chemical family on two genes associated with a class of proteins known as cytochrome P450; the genes produce enzymes that metabolize a broad range of drugs and chemicals.

Scientists have designed nanoparticles that release drugs in the presence of a class of proteins that enable cancers to metastasize.

A contract lab was able to verify a study he co-led with Constantine Mitsiades while at Dana - Farber Cancer Institute, testing an inhibitor of a class of proteins called BET bromodomains.

A well - known class of proteins may fill in the dotted lines that connect signal transduction pathways to the genes they regulate.

Gliadins, a class of proteins found in gluten, are what cause immune reactions in people with celiac disease.

We are interested in three classes of proteins; one which is responsible for the hardening of the cells and their surrounding environment (these are known as fibrotic proteins) in glaucoma and the other which regulates the level of calcium entering and exiting cells.

Sirt4 belongs to a class of proteins, called sirtuins, known to regulate aspects of longevity, metabolism, genome stability, diabetes and neurodegeneration.

So the researchers turned to a class of proteins involved in metabolism, the cytochrome P450s.