Sentences with phrase «classes of antibiotics»

It is then subjected to different classes of antibiotics to determine the sensitivity.

«As veterinarians, we have an ethical responsibility to make sure that we preserve the efficacy of antibiotics for future generations and ensure continued access to certain classes of antibiotics in food animals,» said Robin Falkner, DVM, managing veterinarian at Zoetis.

Now, several generations of people later, its powers are greatly reduced, and successively more toxic classes of antibiotics have been created.

The main classes of antibiotics are listed here.

Significant differences in abundances were found for several resistance genes associated with resistance to several classes of antibiotics, including sulfonamides, fluoroquinolones and aminoglycosides (Figure 2 and Tables S12, S13, S14, S15, S16).

We analyzed whole genome sequences of 1,680 Streptococcus pneumoniae isolates from four independent populations using GWAS and identified probable hotspots of genetic variation which correlate with phenotypes of resistance to essential classes of antibiotics.

Using high - throughput sequencing of DNA from river sediment up and downstream from the Indian treatment plant [11] we identified a high prevalence of resistance genes from multiple classes of antibiotics.

Despite the recognized need for new antimicrobials for clinical use, the reality that only two new classes of antibiotics have been brought to market in the last 30 years and many drug developers have left the field.

To combat these multidrug - resistant bacteria, researchers have been searching for new classes of antibiotics that work by different mechanisms than current drugs.

All these methods together will result in a «resolution revolution» that may contribute to the development of new classes of antibiotics.

Beta - lactam antibiotics, including penicillin, are one of the most widely used classes of antibiotics in the world.

Many classes of antibiotics are effective in treating most strains of the plague, but there is growing concern over strains that are antibiotic resistant.

Isolates of a common poultry pathogen collected from animals in Indian bird markets were mostly resistant to multiple classes of antibiotics.

However, Lipsitch says that if livestock producers simply switch from antibiotics in the classes that McDonald's won't buy to growth promoters from other classes of antibiotics, bacterial drug resistance might remain at its current prevalence or continue to increase.

Investigators found that the E. coli strain from the man's urine sample carried both mcr - 1 and blaNDM - 5 and harbored resistance to several classes of antibiotics, including aminoglycosides, beta - lactams, chloramphenicol, fluoroquinolones, rifampin, sulfonamides, and tetracycline.

The computer simulation models the relationship between bacteria, antibiotics and a method of resistance called beta - lactamase — an enzyme that degrades beta - lactam antibiotics, one of the largest and most - used classes of antibiotics.

Overall antibiotic use is higher in food - producing animals than in humans, but the situation varies across countries and classes of antibiotics.

Nearly three - quarters (74.4 percent) of these bacteria were resistant to multiple classes of antibiotics.

The findings are especially important as Neisseria gonorrhoeae is considered a «superbug» because of its resistance to all classes of antibiotics available for treating infections.

«Over the past half century only two new classes of antibiotics reached the market with few replacement products in the pipeline.

«A new class of antibiotics to combat drug resistance: Newly discovered antibiotic binds to ribosome, disrupts protein synthesis.»

According to BabyCenter, a class of antibiotics that doctors usually avoid prescribing to breastfeeding mothers are the quinolones.

One class of antibiotics is usually avoided during breastfeeding — the quinolones — because some have been associated with damage to tendons when given to adults.

«The reality is that no class of antibiotic has been banned for use, nor do we know of any plans to do so,» explains Dawn Howard.

Unlike other superbugs, a new class of antibiotic - resistant bacteria are gaining their power from easily transferable genes such as NDM - 1

They have also made antimicrobial peptides, which scientists are exploring as a possible new class of antibiotic drugs.

«In this case, the combined expertise of the industry, which has the resources to develop new compounds, and the academia, which has the research and lab capabilities to understand how the compounds work, have enabled the development of this new class of antibiotics,» Mankin said.

A new class of antibiotics, oxazolidinones, became available in the 1990s, and the first commercially available oxazolidinone, linezolid, is comparable to vancomycin in effectiveness against MRSA.

In a randomized, controlled clinical trial — the first of its kind — a multi-institution research team reports that daptomycin, part of a new class of antibiotics currently approved only for use in adults, is effective and well - tolerated in children.

Ups and downs of Ebola vaccines, home - brewed heroin, better solar - cell material, why lobsters turn from blue to red, and the first new class of antibiotics in years top a banner year for chemistry

The research on advanced anaerobic digestion examined a popular class of antibiotics called tetracyclines, finding that these drugs and their breakdown products migrated from the fluid part of the sludge into the solid part during treatment.

Those molecules, which could form a new class of antibiotics, successfully stopped Salmonella, their test bacteria, from growing.

Analysing the samples, the team — involving experts from Newcastle University, the University of Strathclyde and Aarhus University — were able to measure the relative abundance of specific β - lactam antibiotic resistant genes, which can confer resistance to a class of antibiotics that are of considerable medical importance.

In particular, a class of antibiotics called polymyxins (which includes colistin) is used widely in the veterinary sector.

A «game changing» new antibiotic which is capable of killing superbugs has been successfully synthesised and used to treat an infection for the first time — and could lead to the first new class of antibiotic drug in 30 years.

The drug belongs to a class of antibiotics, including penicillin, that destabilize bacterial cell walls, causing them to collapse.

The discovery also provides crucial insights that may one day be exploited to develop an entirely new class of antibiotics, Dr Goddard - Borger said.

To help on this front, in a new paper published in the journal Structure, researchers from McGill University present in atomic detail how specific bacterial enzymes, known as kinases, confer resistance to macrolide antibiotics, a widely used class of antibiotics and an alternative medication for patients with penicillin allergies.

There was one last class of antibiotics to which bacteria had not developed genetic resistance that could spread between them — until now

«New class of antibiotics discovered by chemists.»

A team of University of Notre Dame researchers led by Mayland Chang and Shahriar Mobashery have discovered a new class of antibiotics to fight bacteria such as methicillin - resistant Staphylococcus aureus (MRSA) and other drug - resistant bacteria that threaten public health.

The mystery of why mycobacteria — a family that includes the microbe that causes TB — are extraordinarily hardy organisms is being unravelled by University of Otago, New Zealand, research that offers new hope for developing a revolutionary class of antibiotics to tackle TB.

Until now, a type of bacteria known as Gram negative have remained susceptible to one particular class of antibiotics, called polymyxins.

WHO recommends no longer using quinolones, a class of antibiotics that has become less and less effective.

This new class of antibiotics works against TB by disrupting the function of a part of the cell known as the ribosome, which is responsible for protein synthesis.

St. Jude Children's Research Hospital scientists have discovered a promising new class of antibiotics that could aid efforts to overcome drug - resistance in tuberculosis (TB), a global killer.

«Promising class of antibiotics discovered for treatment of drug - resistant tuberculosis.»

Although the bug was resistant to penicillin, scientists finally stamped it out in the 1960s with a new class of antibiotics, including meticillin.

Using the MaNDi instrument, SNS beamline 11B, they hope to better understand how bacteria containing enzymes called beta - lactamases resist the beta - lactam class of antibiotics.

With the method, the team discovered a new class of antibiotics called malacidins.