Sentences with phrase «classes of drugs»

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio...

Dogs with mutations in the MDR1 gene can exhibit sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications.

The major classes of drugs used in therapeutics, dose response characteristics, mechanisms of action, major physiological effects, toxicity and drug interactions are discussed.

Resources poured into the development of new classes of drugs.

Proton pump inhibitors (PPIs) and nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used classes of drugs, with the former frequently coprescribed to reduce gastroduodenal injury caused by the latter.

«Now you have a way to test efficacy of future vaccines or future therapeutics, whether those therapeutics are drugs that exist already that could be used in a different way for a different purpose, or new classes of drugs such as antibody - based therapeutics that would be more specifically against Zika,» Diamond said.

He used the lab's model and a library of entry inhibitors to untangle whether two classes of drugs exhibit synergy when used in combination.

«This study reveals new pathways in the earliest stages of ALS - FTD and opens the way for developing new classes of drugs to combat this dreadful disease,» says study author Justin Fallon, PhD, a professor of medical science and of psychiatry and human behavior, and a researcher at the Brown Institute for Brain Science.

«This study reveals new pathways in the earliest stages of ALS - FTD and opens the way for developing new classes of drugs to combat this dreadful disease,» said Justin Fallon, a professor of neuroscience at Brown and researcher at the Brown Institute for Brain Science and one of the study authors.

To address the challenges of treating TBI and stroke, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have developed and patented a novel approach combining three distinct classes of drugs to create a multi-drug combination therapy.

«We find that drug - sensitive tumor cells respond in similar ways to some classes of drugs and very different ways to other classes of drugs,» Sorger said.

That difference suggests that drugs based on hydrogen sulfide may work in men who do not respond to Viagra and similar classes of drugs.

Research Despite the limitations of current treatment options, innovations to treating chronic pain have been scarce and limited to tinkering with the delivery of existing classes of drugs.

Few individual ARVs and no classes of drugs were associated with increased risk of birth defects, the researchers found.

Both classes of drugs are used in animals and humans.

Two drug classes: adamantanes (FDA approved in 1966) and neuraminidase inhibitors (oseltamivir, FDA approved in 1999) represent two classes of drugs that target viral an ion channel and a cell surface antigen, respectively, hereby preventing or treating infection.

New classes of drugs that target allergic asthma are emerging or close to market, but Levy notes that these new drugs are unlikely to help patients with non-type 2 inflammation in severe asthma.

He calculates that deaths from three classes of drugs — antipsychotics, benzodiazepines and similar drugs, and antidepressants — were responsible for 3693 deaths every year in Denmark.

Are you looking at creating any entirely new classes of drugs?

The result has been the emergence of strains of infections including tuberculosis and malaria, pneumonia and gonorrhoea that resist all known classes of drugs.

Another issue with pharmaceutical funding has been the lack of development of new classes of drugs in response to the growth of antibiotic resistance.

«When we treat mice with certain classes of drugs, we see enrichment of resistance genes to those drug classes,» Modi said.

The study focused on various classes of drugs used to treat pain (analgesics) and insomnia (hypnotics), as well as drugs to treat anxiety and depression.

Three distinct classes of drugs: dopaminergic agonists (such as D - amphetamine), serotonergic agonists (such as LSD), and glutamatergic antagonists (such as PCP) all induce psychotomimetic states in experimental animals that closely resemble schizophrenia symptoms in humans.

Mental illness has reached crisis proportions, yet we still have no clear links between psychiatric diagnoses and what's going on in the brain — and no effective new classes of drugs.

«There are incredible synergies between the classes of drugs,» he says.

«We have a lot to figure out about how to use this therapy, and we need to treat a few hundred patients in order to get a better sense of how to refine the synergy of these two classes of drugs.

The article I read (years ago) was about narcotics so this may not apply to other classes of drugs.

There are many classes of drugs given during anesthesia, and most of them only make you talkative and amnestic.

or, more radically, for posting their genetic data to an anonymized, shared research database that might be used to identify those at risk for certain diseases or to identify those who respond better to specific classes of drugs, from beta blockers to cancer medicines.

From this theory came a promising class of drugs called checkpoint inhibitors, which effectively release those brakes.

The news underlines a larger trend of a promising new class of drugs that could fundamentally shift the way hepatitis C is treated.

Earlier this month, the FDA approved two other treatments for multiple myeloma, including another kind of monoclonal antibody drug (the same class of drug that elotuzumab is in).

Still, fentanyl belongs to the larger class of drugs that includes these prescription drugs.

While high price tags are common for rare disease drugs, Emflaza is part of a class of drugs called corticosteroids that are used for DMD in other parts of the world.

Tecentriq belongs to a class of drugs called PD - 1 inhibitors, which help the immune system to fight cancer by blocking a mechanism that tumors use to evade attack.

A pharmacologist by training, I also knew that the bisphosphonates — a class of drugs developed for osteoporosis sufferers — were then being tested on OI patients.

Interestingly, theophylline and caffeine are both members of the methylxanthine class of drugs.

Never mind that the agency's own panel of advisers urged that the drug be rejected, citing concerns that it could promote emergence of drug - resistant bacteria and that the drug belongs to an class of drugs needed as a last line of defense against serious human infections.

The new research, published recently as two separate studies in ACS Central Science and the Journal of the American Chemical Society, demonstrates that a new class of drugs called small molecule RNA inhibitors can successfully target and kill specific types of cancer.

«I don't know if I've ever been more excited about a class of drug than I am about [mRNA],» Whitehead says.

«A new class of drug to treat herpes simplex virus infection.»

«In the future, it's possible that a similar class of drug could be tried on humans.

The researchers, however, also found that it may be possible to mitigate these effects with the use of an experimental class of drugs that can block stress.

To bolster the effects of the BRAF inhibitors, recently a new class of drugs was developed to block an enzyme that acts downstream of BRAF / MEK.

Ergotamines, a class of drugs that constrict blood vessels, come from a toxic fungus that attacks rye.

When a class of drugs called triptans became available in the early 1990s, Healy used them, but over time their effectiveness dimmed.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

Various companies are also testing a class of drugs that target both IGF - 1R and the insulin receptor.

In the fall of 2006, the FDA's veterinary advisory committee voted against approving cefquinome, citing concerns that resistance to this vital class of drug could spread from bacteria in beef to hospital superbugs that respond to little else.