Sentences with phrase «clinical application at»

Hands on practical learning and clinical application at each class with qualified clinicians experienced in their class content area.

It is yet another example of how CEH research funded by private donors can translate into cutting - edge clinical application at the UC Davis veterinary hospital.

«But discussing any clinical applications at this point is probably... premature,» Coolen says.

«We look forward to this PET research translating to cutting - edge clinical applications at the UC Davis veterinary hospital.»

Not exact matches

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

At the dawn of the digital health revolution, some argued that fitness trackers were being marketed as a way for companies with long - range ambitions to produce devices with clinical applications to get to revenue in the short - term.

At Mayo, some immunologists work on basic research and others lean more toward the clinical applications of immunotherapy.

The article went on to proclaim this «the first clinical application of iPS cells» and said the results were being presented at a conference in New York.

It could also be relevant to clinical applications — it treats sequence uniqueness as a high priority and thus minimises the risk of potentially unwanted gene modifications, which must be avoided at all costs in gene therapy,» says Graf.

«This finding has immediate clinical applications, because either mutation - PPM1D or TP53 — cause the tumor cells to be resistant to radiation,» said senior author Hai Yan, M.D., Ph.D., a professor of pathology at Duke University School of Medicine.

It has also stopped processing grant applications and accepting new patients at its clinical research center in Bethesda, Maryland, just outside of Washington, D.C.

«Contrary to popular belief, we didn't see any benefit of omega - 3 supplements for stopping cognitive decline,» said Emily Chew, M.D., deputy director of the Division of Epidemiology and Clinical Applications and deputy clinical director at the National Eye Institute (NEI), partClinical Applications and deputy clinical director at the National Eye Institute (NEI), partclinical director at the National Eye Institute (NEI), part of NIH.

«This step in the UK will stimulate debate on legal regulation of germline gene editing in clinical settings,» says Tetsuya Ishii, a bioethicist at Hokkaido University in Sapporo, Japan, who notes that some countries do not explicitly prohibit reproductive applications.

«This is the first demonstration of a shared brain - machine interface, a paradigm that has been translated successfully over the past decades from studies in animals all the way to clinical applications,» said Miguel Nicolelis, M.D., Ph. D., co-director of the Center for Neuroengineering at the Duke University School of Medicine and principal investigator for the study.

The downside includes cultural resistance to Good Clinical Practice (GCP), clinical research process real - time compliance, inadequate information systems leading to unpredictable project milestones, a «no clock» application process in the regulatory machinery, and inconsistent time frames for export / import of clinical trial materials at theClinical Practice (GCP), clinical research process real - time compliance, inadequate information systems leading to unpredictable project milestones, a «no clock» application process in the regulatory machinery, and inconsistent time frames for export / import of clinical trial materials at theclinical research process real - time compliance, inadequate information systems leading to unpredictable project milestones, a «no clock» application process in the regulatory machinery, and inconsistent time frames for export / import of clinical trial materials at theclinical trial materials at the border.

The clinical application of this technology is clear, says lead author Emre Ozkumur, a biomedical engineer also at Massachusetts General Hospital who developed the system with Toner.

A challenge in developing clinical applications is the potential for off - target effects that could result in DNA cleavage at the wrong locations.

«This is encouraging because the safety profile of anti-muscarinic drugs is well - characterized, with more than 20 years of clinical application for a variety of indications in Europe,» said senior study author Paul Fernyhough, PhD, professor in the departments of pharmacology and therapeutics and physiology at the University of Manitoba in Canada.

That's not practical for clinical applications,» says Babak Ziaie, Ph.D, director of the Biomedical Microdevices Laboratory at Purdue University.

«This result has strong application potential» says Dr. Parise, who has just accepted a new position as research scientist at Oculus VR (Facebook): «A deep understanding of multisensory processing opens new clinical perspectives for neurological syndromes that are associated with multisensory impairments, such as Autism Spectrum Disorder and Dyslexia.

«Although this application is not certified at present for use in health care by any regulatory body, our study highlights the potential for smartphone - based diagnostics to aid in clinical decision - making at the patient's bedside,» concludes Dr. Hibbert.

«These findings give a rationale to start autologous transplantation — at least of neural cells — in clinical situations,» says senior author Dr. Jun Takahashi, of the Kyoto University's Center for iPS Cell Research and Application.

Butler hopes to be able to create one type of interneuron at a time, which would make it easier to define the separate roles of each cell type and allow scientists to start the process of using these cells in clinical applications for people who are paralyzed.

At Houston Methodist, fostering innovations with the potential for clinical application is at the very heart of what we dAt Houston Methodist, fostering innovations with the potential for clinical application is at the very heart of what we dat the very heart of what we do.

Refugees seeking asylum in the United States are twice as likely to be granted protection if their application is supported by medical documentation of torture, writes Jules Lipoff, MD, an assistant professor of Clinical Dermatology at the Perelman School of Medicine at the University of Pennsylvania and two colleagues in the March 7, 2016 issue of JAMA Internal Medicine.

«We're forming collaborations with researchers at Loyola and other centers doing basic science research as well as studies with more immediate clinical applications,» said Michael Zilliox, PhD, director of the Loyola Genomics Facility.

«Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease» by name of Hyslop et al. will be published in Nature at 18:00 UK time on Wednesday 8th June, which is also when the embargo will lift.

Speakers at the workshop will discuss progress in sequencing and with other technologies for biomolecular analysis, and their applications in research and clinical settings.

The work on stem cell isolation strategies for future clinical application was recognized with a Medical Technology Innovation award and the Overall Grand Prix Award at the Engineer Technology and Innovation Awards in 2010.

The work builds on and extends continuous acquisition capabilities offered by GRASP, also developed at CAI2R, and has various clinical applications, including in liver and breast imaging, with special benefits for pediatric patients, geriatric patients, and all those who have difficulty performing breath holds.

«These damaging mutations might have some unexpected functional consequence when we're looking at the clinical applications.»

Other applications include designing clinical trials to identify at - risk populations for adverse drug reactions.

The Srinivasan Laboratory at the University of California, Davis, develops novel optical imaging techniques and diagnostics with applications spanning from basic to clinical research.

Applications are invited for a Clinical PhD studentship at the Cancer Research UK (CRUK) Birmingham Centre.

Atul Butte, PhD, who is Priscilla Chan and Mark Zuckerberg Distinguished Professor at UCSF and directs the Institute for Computational Health Sciences, a hub for precision medicine research on campus, echoed the excitement felt across UCSF about moving towards clinical application of precision medicine: «Precision medicine is not just a «nice idea» at UCSF — it is benefitting real people, from cancer patients with unusual tumor mutations to children with undiagnosed genetic diseases.

HERCULES, Calif. — April 14, 2018 — New research showcasing the importance of Bio-Rad's Droplet Digital PCR (ddPCR) technology in clinical applications will be featured in more than 60 presentations at the American Association for Cancer Research (AACR) Annual Meeting in Chicago, April 14 - 18.

«Finding this population of stem cells in a human source represents a major breakthrough for us because it brings us much closer to a clinical application of this therapy,» said Dr. Huard, the Henry J. Mankin Professor and vice chair for Research in the Department of Orthopaedic Surgery at the University of Pittsburgh School of Medicine.

«Taken together, our data underscore the need to more comprehensively understand the mechanisms of CRISPR / Cas9 - mediated genome editing in human cells, and support the notion that clinical applications of the CRISPR system may be premature at this stage,» the Chinese scientists wrote.

In 1996, in response to these concerns, Varmus, then director of NIH, impaneled a group of experienced clinical investigators and academic health center administrators to make recommendations that might guide the NIH toward policy changes to alleviate the concerns in the clinical research community.14 Several of the panel's recommendations have been implemented, including increased support of the General Clinical Research Center budget, expanded support of training in clinical research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented rclinical investigators and academic health center administrators to make recommendations that might guide the NIH toward policy changes to alleviate the concerns in the clinical research community.14 Several of the panel's recommendations have been implemented, including increased support of the General Clinical Research Center budget, expanded support of training in clinical research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented rclinical research community.14 Several of the panel's recommendations have been implemented, including increased support of the General Clinical Research Center budget, expanded support of training in clinical research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented rClinical Research Center budget, expanded support of training in clinical research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented rclinical research, and the establishment of NIH - sponsored educational debt relief programs for clinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented rclinical investigators.15 - 18 The panel also recommended restructuring of NIH peer review groups so that patient - oriented grant applications would be evaluated by study sections in which at least half the grant applications involve patient - oriented research.

Consequently, human subject concerns raised at the time of review may have contributed to, although do not totally explain, the less favorable review outcomes for clinical applications.

Today the FDA issued a Complete Response Letter regarding PTC Therapeutics» application for ataluren, noting that «an additional adequate and well - controlled clinical trial (s) will be necessary at a minimum to provide substantial evidence of effectiveness.»

At the same time, the President of the United States and the Director of NIH are spearheading a new Precision Medicine Initiative (PMI) to create a cohort of a million individuals that will support research into precision medicine and its clinical application.

«We are pleased to contribute to this important initiative, which will facilitate the application of new strategies to the clinical care of stroke survivors,» said A.M. Barrett, M.D., director of Stroke Rehabilitation Research at Kessler Foundation, and chief of NeuroRehabilitation Program Innovation at Kessler Institute.

He is also visiting lecturer for Telemedicine and Clinical Applications of Computational Medicine at the Technical University Munich.

(3) Future clinical application of human germline genome editing should not proceed unless, at a minimum, there is (a) a compelling medical rationale, (b) an evidence base that supports its clinical use, (c) an ethical justification, and (d) a transparent public process to solicit and incorporate stakeholder input.

Basic research in cancer biology is often viewed as «high risk,» in part because the clinical applications of a given research project might not be clear at the outset.

The Integrative Pain Management course offers an in - depth look at the current state of pain management; including challenges, latest evidence - based integrative therapies, and clinical applications.

The therapeutic clinical applications of probiotics have been limited to a handful of strains out of the more than 7000 at last count.

Scientific exploration at the Center for BrainHealth ® is leading edge, improving lives today and translating groundbreaking discoveries into practical clinical application.