Sentences with phrase «clinical endometrial cancer»

Not exact matches

According to the authors, the new findings provide a roadmap for future clinical trials for endometrial cancer.

Adding metformin to a combination of everolimus plus letrozole for women with advanced or recurrent endometrioid endometrial cancer might offer clinical benefits.

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

Currently, the CDK9 inhibitor flavopiridol is being evaluated in several phase I and II clinical trials for its anti-cancer effects either as a single agent or in combination with other drugs in treatment of esophageal cancer, B - cell chronic lymphocytic leukemia, endometrial carcinoma, recurrent / metastatic squamous cell carcinoma and most relevantly, previously treated locally advanced or metastatic breast cancer (http://www.cancernetwork.com/review-article/current-clinical-trials-flavopiridol/page/0/2).

In fact, one comprehensive analysis of several clinical trials found a reduced risk of bladder, breast, colorectal, endometrial, gastric, lung, ovarian, pancreatic, prostate and renal cancer.

In clinical trials, Raloxifene (also used for osteoporosis) has been shown to cut the risk of breast cancer by 70 percent without causing endometrial cancer.