Sentences with phrase «clinical field trials»

Following American Heartworm Society and Companion Animal Parasite Council guidelines, dogs that have stabilized Class 1, 2 or 3 heartworm disease should receive three doses of DIROBAN.3 - 4 Laboratory and clinical field trials show that treatment with DIROBAN results in the reduction and / or clearance of D. immitis infection.5 DIROBAN is now available to U.S. veterinarians.

In the clinical field trials ears were not cleaned, and many animals still had debris in their ears after the second dose.

In clinical field trials with ivermectin / pyrantel, vomiting or diarrhea within 24 hours of dosing was rarely observed (1.1 % of administered doses).

Not exact matches

In the last few years, the number of clinical trials in this field has exploded, along with the flurry of money from Big Pharma and investors, stirring optimism in the fight against cancer.

The new Alzheimer's framework may not be much of a surprise given numerous, high - profile, late - stage clinical trial failures in the field by companies like Eli Lilly and Merck, and the decision by other companies (such as Pfizer) to back away from the risk - prone field.

Through talking to experts in the field over the past year, Gates said he had identified five areas of need: Understanding better how Alzheimer's unfolds, detecting and diagnosing it earlier, pursuing multiple approaches to trying to halt the disease, making it easier for people to take part in clinical trials of potential new medicines, and using data better.

Katherine High, Spark's president and chief scientific officer, expressed her enthusiasm for the early clinical data related to SPK - 8011: «The encouraging start of our SPK - 8011 clinical trial reinforces the strength of our gene therapy platform, delivers human proof - of - concept in a second liver - mediated disease — a significant achievement in the gene therapy field — and positions us well to potentially transform the current treatment approach for this life - altering disease with a one - time intervention.»

«Despite huge efforts in the field of nanomedicine, fewer nanoparticle technologies than expected have made it to clinical trials.

Another field that might appeal to your desire to work in a role with clinical applications is that of clinical trials.

Ishii notes that if the clinical trial begins as planned, it would be the latest in a series of firsts for China in the field of CRISPR gene editing, including the first CRISPR - edited human embryos, and the first CRISPR - edited monkeys.

Is a new clinical trial with embryonic stem cells the breakthrough the field has been waiting for?

Clinical trials that charge enrollees to participate are ostensibly aimed at giving patients early access to promising therapies — often in the fields of stem cells or aging reversal — that are too unusual or have too little profit potential to get funding from traditional sources such as companies, foundations, or the National Institutes of Health.

Perry says, «Because our society supports medical investigations with the hope of affecting people's lives for the better, this field will increasingly be part of clinical trials and clinical medicine.»

Now, newly published results from a closely watched clinical trial are being hailed as a big win by some in the Alzheimer's treatment field.

«While the present report suggests that optimal outcome measures for FXS are not yet fully developed, the recent failures of clinical trials in the FXS treatment field represent an opportunity to implement novel study designs and methodologies,» concludes Budimirovic.

Less than a decade after a powerful gene - silencing method — RNA interference, or just RNAi — was discovered, the field's pioneers have not only won the 2006 Nobel Prize in Physiology or Medicine but have also helped launch an entirely new class of drugs into human clinical trials.

«The rapid advancement of Zika vaccine candidates into clinical trials reflects the uniquely focused and effective collaboration among scientists in the field to address this important global problem,» said Barouch.

Regenerative neurobiologist Malin Parmar, who heads one of the teams at Lund University in Sweden, says that the groups «are all rapidly moving towards clinical trials, and this field will be very exciting in the coming years».

Co-author and Chair of the IOF Committee of Scientific Advisors, Professor Cyrus Cooper added, «Steady advances are being made in this field and we look forward to a promising ongoing initiative to bring all BTM results from clinical trials in osteoporosis together in one individual meta - analysis.

The field has experienced monumental challenges developing new and effective drug therapies, not the least of which was the discovery that — until recently - clinical trials were conducted where up to 30 % of participants did not have the Alzheimer's disease - related brain change targeted by the experimental drug.

«The problem in the cancer field is that they have many high - profile papers of clinical trials [that] all failed in some way,» he said.

With its innovative Clinical Trials Network, influential annual meeting and high - impact journals, SNMMI encourages and facilitates research and science for the nuclear medicine and molecular imaging field.

Just hours before this latest Cleveland Clinic Lerner Research Institute study was published, another blow to the field came when Merck announced it was discontinuing a Phase 3 clinical trial into a drug called verubecestat, following a recommendation suggesting, «it was unlikely that positive benefit / risk could be established if the trial continued.»

Pedro de Noronha Pissarra, chief executive officer of Biotecnol said: «We're very proud to work with Cancer Research UK on the development of advanced clinical trial approaches in this competitive and highly promising field of immuno - oncology.

Although this field is still relatively young, evidence for clinical efficacy has been observed and continued progress seems assured, as clinical trials continue to yield insights into how gene therapy can be applied and improvements are made in gene therapy tools.

This article also highlights the needs of long - term follow - up of clinical trials in this field.

In order to obtain the comprehensive designation, which is the highest ranking the National Cancer Institute (NCI) gives, a center must meet strict criteria that include a strong core of basic laboratory research in several fields, the ability to translate those research findings into therapies that can one day be used to treat patients, a program of high - priority clinical trials, and a commitment to community service and outreach activities related to cancer prevention and control.

She has over 10 years of experience in the research field in various areas including clinical trials studies, neuroimaging studies, drug addiction, and developmental psychology.

Precision medicine, immunotherapy, clinical trials... 2016 will be a year of many changes in science and medicine — and nowhere is this more obvious than in the field of cancer research.

This additional non-dilutive EUR 7.5 million will partially fund the clinical trial of our proprietary A2A antagonist drug candidate, which is in the exciting field of cancer immunotherapy.

Therapies applying this paradigm to clear β - amyloid protein (Aβ) plaques and soluble aggregates from patients with Alzheimer's disease (AD) is an extremely active field of research, with multiple active and passive Aβ vaccines currently in human clinical trials.

In September 2016, he established the Regenerative Outcomes Foundation, a non-profit project that will provide direct grants to stem cell patients participating in FDA - approved clinical trials, train patients as ambassadors between interests represented in the Regenerative Medicine field, inspire the public with a Pioneers of Hope Interview Series, educate providers at online «Grand Rounds Webinar» events, and advance a Federal cell therapy outcomes registry.

Latest clinical trial developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from non-academic institutions April 01 — May 31, 2017.

Results of 2 cellular immunotherapy trials I'd like to bring your attention to two recently published clinical studies in cancer cellular immunotherapy field.

Clinicians and investigators in the fields of veterinary and human endocrine oncology, clinical trials, pathology, and drug development will be joined in this consortium, in order to improve knowledge, development of, and access to naturally occurring canine endocrine tumours, as a model for human disease.

And because several HDAC - blocking drugs are commonly used in other fields of medicine, including neurology, it proved relatively straightforward for physicians to take some of these drugs into clinical trials in patients with SMA.

Through seminars, workshops, working groups, and online consensus - building projects supported by immunological and clinical data from cancer immunotherapy trials, the Consortium works to address several of the key issues facing the cancer immunotherapy field.

Recent clinical trials, such as the HVTN 505 study that was stopped because the vaccine was shown to be ineffective at preventing HIV, have generated new challenges to the field.

It has been set up to address the problem of fragmentation in the rare disease research field, where individual efforts often have poor interoperability and do not systematically connect data across the levels of clinical phenotype, genetics and omics data, biomaterial availability and research / trial datasets.

Given that clinical trials that targeted Aβ and tau have yet to succeed, it's time the field focus its energies on apoE4.»

With several human clinical trials involving the CRISPR gene - editing process moving forward, the original study resulted in a flurry of criticism from many scientists in the field.

Human clinical trials are becoming an increasingly important part of the fast - changing field of implantable brain - computer interface (BCI) research.

Extended - field radical radiotherapy in advanced Hodgkin's disease: short - term results of 2 randomized clinical trials.

«Based on the clinical evidence we've gathered over the past decade in our cancer vaccine trials,» Old said, «and in light of data from a variety of trials by others within the field, we believe therapeutic cancer vaccines will increasingly emerge as one of the safest and most powerful ways to combat a variety of cancers.»

Late last year the preeminent firm in the field, Silicon Valley's Geron, abdicated its leadership position in the midst of the first - ever FDA - approved clinical trial for an embryonic - stem - cell therapy.

They publish full - length regular articles reporting the results of clinical trials or other experimental procedures, as well as short communications on minor advances in the field and reviews covering topics of special interest.

A clinical human trial recently published in The New England Journal of Medicine in August of 2017 may tip a few more in the medical field into accepting the current awareness that inflammatory damage is a major cause of heart and cardiovascular disease, and cholesterol is trying to patch up the damage before the vessel begins to leak or rupture.

, Randomized, Double - Blind Clinical Trial to Assess the Acute Diuretic Effect of Equisetum arvense (Field Horsetail) in Healthy Volunteers, 2014

The School comprises of many experts in the field of public health, producing innovative and dynamic research and projects in the areas of epidemiology, biostatistics, clinical trials, clinical registries, evidence synthesis and health social science.

We need those clinical and field trials in the shelter environment... to determine the safety and efficacy of this drug.»