Sentences with phrase «clinical grade cell»

Review of «Footprint free human iPSCs from articular cartilage with redifferentiation capacity - a first step towards a clinical grade cell source» from Stem Cell Translational Medicine by Stuart P. Atkinson

Not exact matches

Although the mix - up is being examined, the center has halted supplies of some of its iPS cells to researchers across Japan; the error also set back by a few years a CiRA project to produce clinical - grade platelets from iPS cells.

However, this approach is inefficient and complicated, relies on ill - defined cellular signals, lacks reproducibility, and is not scalable or suitable for clinical - grade cell manufacturing.

To make «clinical - grade» cells, scientists produced them without the use of any of the animal cells or products typically needed, and did so under certified manufacturing conditions.

His own team expects to deposit a clinical - grade human embryonic stem - cell line into the UK Stem Cell Bank in 2cell line into the UK Stem Cell Bank in 2Cell Bank in 2012.

And a Singapore - based group created six clinical - grade cell lines in 2007, also using animal products.

Much of the money went into infrastructure that will enable the creation of additional clinical - grade cell lines, he says.

Moreover, cell lines vary in their ability to make different tissues, such as heart muscle or cartilage, so a suite of clinical - grade lines is needed, Braude says.

Elsewhere in the United Kingdom, researchers at the University of Sheffield and Roslin Cells, a company based in Edinburgh, are also establishing clinical - grade lines.

Blood describes a diverse group of cells that includes those that carry oxygen, heal wounds, and fight off infection, and the production of clinical grade blood has remained a major goal of reprogramming science.

The development of these clinical grade stem cells, the release notes, «removes a significant barrier in the development of cell - based therapies.»

The impact of Ex Vivo clinical grade activation protocols on human T - cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.

To develop criteria, procedures and protocols for reproducible, safe and large - scale manufacture of stem cells and their progeny to clinical grade standard;

Clinical Cell Processing News is a series about new protocols, products and techniques for clinical - grade cell processing and manufaClinical Cell Processing News is a series about new protocols, products and techniques for clinical - grade cell processing and manufacturCell Processing News is a series about new protocols, products and techniques for clinical - grade cell processing and manufaclinical - grade cell processing and manufacturcell processing and manufacturing.

His lab has pioneered the generation of clinical grade induced pluripotent stem (iPS) cells using non-viral reprogramming methods such as direct delivery of reprogrammed proteins and novel episomal methods, and has recently identified novel mechanisms underlying metabolic reprogramming during human induced pluripotency.

Unfortunately, the standard tools for assessing risk of metastasis — such as the size of the tumor, its grade, the presence of estrogen receptors and the proportion of dividing cells — are «insufficient,» note the authors, «for clinical decision making.»

Scientists from King's College London announced that they were depositing the first clinical grade stem cell lines developed for publicly - funded research in the UK Stem Cell Bcell lines developed for publicly - funded research in the UK Stem Cell BCell Bank.