Sentences with phrase «clinical infections as»

Not exact matches

Just this month, as part of the first large - scale clinical trial of its kind, researchers working in rural India found that newborns who were given a synbiotic were at a substantially lower risk of developing sepsis, a potentially fatal condition characterized by severe infection.

Despite microbial contamination of birth pool water during delivery, antibiotic prophylaxis, as indicated by clinical and laboratory suspicion of infection, was administered to only 0.98 % of babies after water birth versus 1.64 % of those after land delivery...

MRSA Action UK does not however support or agree with Professor Mark Baker's comment in today's media that NICE is considering bringing antibiotics into the existing bonus scheme for GP's not to prescribe these drugs, this is both wrong and immoral as some patients will always require treatment for infections, it is the clinical need that needs to be ascertained and the correct diagnosis determined and appropriate treatment given that needs to be correct.

Although it is not yet in clinical trials, this nanoparticle could be an important weapon against superbugs such as MRSA, a common bacterial infection that claims 19,000 lives in the U.S. every year.

«We are pleased to have demonstrated such a potent and durable immune response to the vaccine,» said the study's lead author, Sita Awasthi, PhD, a research associate professor of Infectious Diseases at Penn. «If found effective in clinical trials, the vaccine will have a huge impact on reducing the overall prevalence of genital herpes infections and could reduce new HIV infections as well, especially in high - burden regions of sub-Saharan Africa.»

Also recruited were 26 healthy controls, also split nearly evenly between the sexes and about the same ages as the other group, with no clinical history of Lyme disease symptoms and no antibodies to Borrelia burgdorferi that would indicate past or current infection.

But only one published clinical trial has shown that copper lowers infection rates — by as much as 58 % — in hospitals.

The attendees developed a list of top research priorities and a research agenda for exercise in solid organ transplant, which includes the need to conduct large multicenter intervention studies, standardize measures of physical function in clinical trials, examine the benefits of novel types of exercise, and assess the effects of exercise on measures such as immunity, infection, and cognition.

This small molecule is in clinical trials against cancer and has high specificity and good pharmacological properties, which could warrant its further development as antiviral drug for treatment of pH1N1 virus infection,» Dr. Oxana Denisova says.

«As the price and accuracy of rapid diagnostic tests and other diagnostic instruments improve, I think we have a chance to really make a difference in clinical settings facing huge burdens of acute undifferentiated febrile infections that I believe are being misdiagnosed,» said Stoler, who also holds a position in the Department of Public Health Sciences at the UM Miller School of Medicine.

When Theravance, the company in South San Francisco, California, that developed the drug, designed the large phase III clinical trials needed for approval, the FDA simply required a demonstration that the drug eliminated symptoms of infection as reliably as the approved antibiotic vancomycin.

The reliably high percentage of those who develop viremia following exposure to this challenge virus is another advantage — when most or all volunteers develop viremia or other signs of infection, clinical trials can enroll relatively small numbers of people but still achieve answers to such questions as whether a candidate vaccine protects against infection, she noted.

«We have documented the full clinical spectrum of acute Zika virus infection in 12 % of all such cases imported to Canada from the Americas over a 1 - year period, including adverse fetal and neurologic outcomes, as well as sexual transmission,» write the authors.

But as part of a clinical trial led by Hall, she is one of the first kids in the country to receive a drug called GM - CSF that researchers hope will boost her immune system enough so that it can fight off potential infections.

Further testing and human clinical trials are needed to determine if favipiravir, also known as T - 705 and Avigan, could effectively treat Lassa virus infection in people.

«The best thing would be to have this drug withdrawn from the market, and if it's not, there should at least be mandatory testing because we know that people don't take this as prescribed,» he says, citing a Truvada clinical trial in Africa that was ended prematurely because the drug was not preventing infection.

In healthy individuals HCMV establishes lifelong latency, but in immunocompromised patients, viral reactivation can lead to severe clinical symptoms, such as disseminated viral infection, blindness and potentially cancer.

The safety and efficacy of these methods have been well established through long - term clinical outcomes studies in the field, with the nasal lining protecting the brain from infection just as the blood brain barrier has done.

For us as a team, it's a bit of a holy grail to be able to get a 100 % when you have clinical symptoms and infection has been detected.»

Experimental animal models have been used to investigate many aspects of the clinical disease such as the sex bias in myocarditis where testosterones in males promote autoimmunity in the heart while estrogens in females suppress virus infection and autoimmunity.

Nosocomial infections, such as methicillin - resistant Staphylococcus aureus (MRSA), pose a major challenge to clinical management and health policy [87].

Phenotyping encompasses a standardised set of more than 600 clinical parameters, and covers key biomedical areas such as reproduction, development, infection and immunity, musculoskeletal system, metabolism and endocrinology.

In the past two weeks we've learned of a major advance in ongoing efforts to halt the spread of HIV, two separate clinical studies have reported that a daily regimen of a pill called Truvada as a pre-exposure prophylaxis (PrEP) is highly effective in preventing infection in high risk groups.

Newer CXCR4 antagonists are under clinical evaluation for therapeutic intervention in various cancers, hematologic and vascular disorders, HIV infection, and other immune system disorders involving the modulation of the SDF - 1 / CXCR4 axis, such as rheumatoid arthritis and lupus [54 - 56].

Undiagnosed coinfection with a second RFLP type [19] or with another tickborne infection, such as human granulocytic ehrlichiosis [4], may have contributed to the overlap in clinical symptoms observed among persons infected with the different subtypes (table 2).

Review: Excess iron intake as a factor in growth, infections, and development of infants and young children — Bo Lönnerdal — American Journal of Clinical Nutrition

The latter work addresses questions including whether infection with different serotypes is associated with distinct types of T cell responses, whether any HLA alleles are associated with pathogenesis or protection, and whether vaccination with a formulation in clinical trials is associated with T cell responses similar to those following infection that might serve as correlates of protection.

Contracted through the bite of an infected mosquito or through sexual or other modes of transmission, Zika virus (ZIKV) infection can be prenatally passed from mother to fetus.1 The virus was first identified in the region of the Americas in early 2015, when local transmission was reported in Brazil.2 Six months later, a notable increase in the number of infants with congenital microcephaly was observed in northeast Brazil.3, 4 Clinical, epidemiologic, and laboratory evidence led investigators to conclude that intrauterine ZIKV infection was a cause of microcephaly and serious brain anomalies.5 - 7 However, as with other newly recognized teratogens, these features likely represent a portion of a broader spectrum.

Methods: WGS data from 229 L. pneumophila ST1 isolates were analyzed, including 99 isolates from the water systems of 17 hospitals and 42 clinical isolates from patients with confirmed or suspected hospital - acquired infections, as well as isolates obtained from or associated with community - acquired sources of Legionnaires» disease.

The infection status among the six clinically normal animals is unknown, and so mortality rate was approximated as 40 % of tigers displaying clinical signs.

MYTH: Antibiotics impair birth control The only antibiotics known to affect how well some hormonal contraceptives work are Rifadin and Rimycin, used to treat serious bacterial infections such as tuberculosis, according to NPS MedicineWise clinical adviser Dr Philippa Binns.

But I can tell you this right now, these actually actually tests work, and have come about through my clinical experiences with over 20,000 patients who I have seen with yeast infections (as of June 2014)

As a clinical nutritionist (40 + years) and a «health detective,» I have found that jawbone infection (s) caused by a root canal (s) is very common in cases of Hashimoto's / Grave's and other autoimmune conditions.

If you're finding your child is suffering from viral infections such as diarrhoea, ear infections and respiratory tract infections you will be pleased to hear that probiotics have been found to reduce susceptibility of these in clinical trials.

Although there are numerous claimed benefits of using probiotic supplements, such as maintaining gastrointestinal health, in part by lowering risk of and severity of constipation or diarrhea, and improving immune health, including lower risk of and severity of acute upper respiratory tract infections, i.e., the common cold, such claims are not all supported by sufficient clinical evidence.

Of course, other clinical manifestations must also be present to establish the cause of your cat's excessive urination as urinary tract infection.

Beginning at eight weeks old, have your veterinarian deworm your kitten as needed to prevent clinical signs associated with infection, as well as further loss of fluid and weight.

The persistence of clinical signs (increased urination, appetite and thirst) as well as the development of chronic complications (such as ketoacidosis, fatty liver, pancreatitis, cataract, bacterial infections) are directly related to the severity and duration of hyperglycemia.

Although some of the dogs showing clinical disease were recently boarded or at doggie daycare facilities, this should not be taken as an indication that this virus is only spread at boarding kennels or that boarding your dog or taking it to daycare will result in infection.

Positive FHV - 1 test results (virus isolation, immunofluorescence techniques, and conventional PCR assays) do not differentiate subclinically infected cats from those with clinical disease as a result of FHV - 1 infection.

Fecal testing is important to prevent parasites, but is also very important if your pet has clinical signs of infection, such as diarrhea or vomiting.

For example, one shelter may elect to treat only those cats that were picked up as strays, those selected for adoption directly from the shelter, or those with clinical signs of disease that could be attributed to heartworm infection.

There is no scientific evidence that any treatment intended to kill adult heartworms in dogs will safely do so in cats and increase their infection survival rate.6 Administration of melarsomine, the compound labeled for treatment of adult heartworms in dogs, is not as effective in cats and its administration is frequently fatal.7, 8 For these reasons, «treatment» of feline heartworm disease focuses on controlling clinical signs related to the disease process.

Clinical Signs Early in the course of infection, the virus is carried to nearby lymph nodes, where it reproduces in white blood cells known as T - lymphocytes.

2 Dogs were considered to have disease as a result of CIV H3N2 infection if they had two or more clinical signs observed on two or more consecutive days.

Common clinical signs are associated with upper respiratory infection signs such as sneezing, eye discharge and nose discharge (similar to the common cold in humans).

The time from infection to clinical signs ranges from as short as one day to several days.

RHINOTRACHEITIS (feline herpes virus 1) & CALICI VIRUSES are the primary stimulants of upper respiratory infection in the feline species, capable of causing clinical signs localized to the upper respiratory system such as sneezing, ocular discharge, and oral ulcerations as well systemic infections in more virulent strains of calici viruses.

Diagnosis: Clinical signs and breed are suggestive, but other causes of patchy hair loss include bacterial demodex, or ringworm infection, or hormonal diseases such as hypothyroidism and Cushing's disease.

Clinical signs and, possibly, thoracic radiographic findings are similar in cats with abbreviated heartworm infections and those with other causes of bronchial disease, such as feline asthma.