Sentences with phrase «clinical outcome of patients»

You know, you're looking at things of, «hey what can I do to actually change a clinical outcome of my patients.»

The findings suggest that targeting newly discovered pathways could be an effective approach to improving the clinical outcome of patients with BRAF inhibitor - resistant melanoma tumors.

The researchers call for more targeted studies to assess the clinical outcomes of patients who test positive for metal sensitization.

Using an array of techniques, including RNA sequencing and targeted gene expression profiling, the researchers searched for links between gene activity and protein production in these tumors and the clinical outcomes of patients.

The present study was aimed to investigate the relationship between the expression of collagen type V alpha 2 chain (COL5A2) and clinical outcomes of patients with bladder cancer.Chi - square test and log - rank - based survival analysis were performed to assess the correlation of COL5A2...

Not exact matches

Ashish Jha, the senior author of the JAMA Internal Medicine paper, points out in a blog post that there are reasons why women doctors might well deliver better care, citing research to suggest that they might adhere more closely to established clinical practice guidelines and that patients often report better personal experiences (something that ultimately might lead to better outcomes).

Currently, no PBM is delivering comprehensive and patient - specific actionable information real - time to prescribers, pharmacists, members, and clinical / pharmacy staff of payer to create better health outcomes.

While patient safety, clinical informatics, data analytics, and improving quality outcomes remain top of mind among hospital - based healthcare IT leaders, cybersecurity and data privacy and security issues have risen nearly to the top of the list of concerns of those leaders.

Towne Health is leading the way in Advancing the Patient ExperienceTM by providing an array of services that support and complement clinical outcomes, including healthcare parking and transportation, patient transport, patient experience solutions and employee support sePatient ExperienceTM by providing an array of services that support and complement clinical outcomes, including healthcare parking and transportation, patient transport, patient experience solutions and employee support sepatient transport, patient experience solutions and employee support sepatient experience solutions and employee support services.

A search of Pubmed [a data base containing all medical journal articles] for platelet rich plasma yields 6,811 articles, but less than 20 are clinical studies evaluating patient outcomes for orthopedic sports medicine conditions.

We compared outcomes after medical versus surgical management of biliary tract disease in pregnant patients.We reviewed the clinical course of patients with symptomatic cholelithiasis during pregnancy from 1992 to 2002 at two university hospitals.Seventy - six women with 78 pregnancies were admitted with biliary tract disease.

He is an expert in the use of systems - based methods to improve patient outcomes, a leading researcher in use of large scale clinical laboratories and electronic health records to improve the effectiveness and efficiency of care, and a nationally recognized thought leader in the very methods needed to transition to the future of lower - cost, more patient - centered, health care for the 21st century.

Let me point to 10 things that I sketched out this morning: too much money spent on administration and bureaucracy and not enough on front - line patient care; too little patient - centric information to inform decision making; too little innovation; too little clinical input into decision making; too much inertia and hostility to reform, as we have seen today; too much process - driven target culture distorting clinical decision making; falling productivity; poor outcomes across a range of clinical indicators; too often, weak commissioning of servicing; and widening health inequalities in the past 10 years, in addition to the scandals that occurred in Staffordshire and Kent.

Future resources from the NCI Center for Cancer Genomics (CCG), which oversees TCGA and other activities, will support more translationally focused research, including databases with genomic information on clinical samples linked to outcomes of their patient donors.

Professor Voors concluded: «The major finding from this substudy of the RELAX - AHF trial is that diuretic resistance is a clinical problem that leads to worse in - hospital and early post-discharge clinical outcomes in patients with acute heart failure.

The TOPCAT trial is the first randomized, double - blind trial to assess the effect of spironolactone on clinical outcomes in these patients with heart failure and preserved ejection fraction.

A late - breaking clinical trial, known as the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, to be presented at the American Heart Association (AHA) Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump function).

While randomized clinical trials are the gold standard of clinical research, such trials are not feasible for testing anesthesia technique in joint replacement surgeries, because the low incidence outcomes would require a huge number of patients.

Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.

Clinical trials testing various cancer vaccines have failed miserably; in one, a melanoma vaccine called Canvaxin did not improve the survival of patients, an outcome that ultimately forced the drugmaker to sell itself to another firm.

In 22 percent of cases, the additional clinical information found in the EHR was rated as «possibly» having a clinically significant impact on the interpretation of the head CT. «This study exemplifies the power of EHR's and their potential impact on patient care and positive outcomes.

This is important because the proportion in which the de novo mutation is present in a patient, as well as the type of cells in which it occurs, may not only determine the clinical outcome of a disease for the patient, but also affect the risk of the parents having another child with the same disease in future pregnancies.

«STS public reporting uses detailed clinical registry data and outcomes that have been risk adjusted, meaning that the results take into account the condition of the patient at the time of surgery and whether or not there were other health problems, such as diabetes.»

Professor Pincus and her team are now planning a larger clinical trial to explore whether the combination of physiotherapy and psychology will improve outcomes for patients and reduce treatment costs in the long term.

With survival rates improving for ARDS patients, understanding and improving their quality of life outcomes is a clinical and research priority, according to the study's principal investigator Samuel M. Brown, MD, MS, FASE, director of the Center for Humanizing Critical Care at Intermountain Medical Center.

An investigation into how patient outcomes are assessed in clinical trials has revealed a worrying lack of consistency, raising concerns about funding being wasted on the acquisition of poor quality data.

The study, Developing an Interventional Stroke Service: Improving Clinical Outcomes and Reducing Cost and Delivering Great Cost Savings Benefits to Health Economy, conducted at the University Hospital of North Midlands, Stoke - on - Trent, U.K., found that mechanical thrombectomy (the use of a device to retrieve a clot from the vessel) in the treatment of stroke reduced the average stroke patient's hospital stay to 14 days when compared to previously recorded 90 days.

The UB researchers are conducting a longitudinal, five - year study of these patients focused on the relationship between cerebral microbleeds, advances in magnetic resonance imaging and clinical outcomes.

«This promising clinical trial is the next step in a series of trials to identify new drugs that are fundamentally shifting the horizon — improving the outcome for patients with advanced differentiated thyroid cancer.»

The ideal comparison of trauma center vs. non-trauma center outcomes would be a clinical trial in which patients are randomly assigned to one type of hospital or another.

In three new studies in the current issue of the International Journal of Infectious Disease, researchers reported on clinical outcomes in the Kingdom of Saudi Arabia (KSA), how long patients will shed virus during their infections, and how the Sultanate of Oman is dealing with cases that have appeared there.

The researchers next will turn to analyzing the presence of myoferlin in samples from numerous human tumor types available in an Ohio State tissue bank, which will allow them to compare protein levels in tumors to clinical outcomes for the patients who provided the samples.

RELAX - AHF was a randomised, double blind controlled trial that evaluated the effects of a 48 - hour infusion of the intravenous drug, serelaxin, on clinical outcomes in 1 161 patients admitted to hospital for acute heart failure.

«Detecting genetic associations in cases of acute viral bronchiolitis is the first step toward the development of tests to predict the possible clinical outcome for each patient diagnosed with the disease soon after arrival at the emergency room,» said Fernando Augusto de Lima Marson, a researcher at FCM - UNICAMP and one of the authors of the article.

Principal Investigator John Morris, MD, clinical co-leader of the Molecular Therapeutics and Diagnosis Program for the CCC, co-leader of the UC Cancer Institute's Comprehensive Lung Cancer Program, professor in the division of hematology oncology at the UC College of Medicine and UC Health medical oncologist, says a number of antitumor vaccines have shown promise for causing immune responses against tumor antigens to improve patient outcomes.

The clinical characteristics and outcomes of asymptomatic AF patients were different between the PAF and SAF groups.

«In conclusion, the study by Carrero et al in this issue of JAMA provides the best evidence to date that vitamin K antagonists [anticoagulants] are associated with improved clinical outcomes and no significant increased risk of bleeding in patients with myocardial infarction and atrial fibrillation with advanced CKD.»

Patients with CSA are good candidates for the remede ® system which can improve their sleepiness, quality of life and potentially their clinical outcomes.»

In a new study, a hospital surveillance program focusing on reducing the risks of sepsis, known as the two - stage Clinical Decision Support (CDS) system, was found to reduce the risk of adverse outcomes, such as death and hospice discharge for sepsis patients, by 30 % over the course of one year.

«TOPCAT is the first randomized, double - blind trial to assess the effect of a treatment - spironolactone - on clinical outcomes in this patient demographic.»

However, in analyses that accounted for important patient characteristics such as age, sex, comorbidities, and the reason for hospitalization, the quality of care of the discharging hospital and SNF facility characteristics, outcomes did not vary meaningfully across SNFs that differed in staffing ratings or their performance on clinical measures related to pain or delirium.

Further research incorporating patient outcomes and data from actual clinical interactions is warranted to clarify the effect of clinician implicit bias on the provision of health care and outcomes,» the study concludes.

When the researchers matched this data with clinical outcomes for more than 4,600 patient specimens in medical databases, they found these subtypes were associated with different levels of disease progression.

In the patients they studied, this subtype showed a high likelihood of spreading and progressing to poor clinical outcomes, including fatalities.

«Emergency department crowding is clearly linked to worse patient care and worse outcomes, including higher mortality rates, higher rates of complications, and errors,» said Jesse M. Pines, M.B.A., M.D., director of the Office for Clinical Practice Innovation, professor of emergency medicine and health policy at the GW School of Medicine and Health Sciences.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

To investigate, Csaba Kovesdy, MD (Memphis VA Medical Center and the University of Tennessee Health Science Center) and his colleagues examined information from the national VA research database and looked for associations between blood pressure and various clinical outcomes — coronary heart disease, stroke, kidney failure, and death — in more than 300,000 patients with CKD.

Since blood samples are taken and frozen with many clinical trials, this allows them «almost a bit of a time machine» to go back and explore questions around pain or neuropathy to run tests on neurons created from blood samples of patients taken in past clinical trials where responses and outcomes have already been recorded.»

The USIDNET registry gathers variables including clinical, laboratory and outcome data, which together provide a health survey of the relatively small number of patients affected by primary immunodeficiency disorders.

«The majority of cancer patients we work with are excited to participate in clinical trials that could benefit future patient outcomes down the line,» says co-senior author Bryan Allen, who led the clinical side of the study.