The authors suggest that therapies targeting TP53 mutations may yield better
clinical outcomes for patients with HPV - inactive tumors.
The researchers next will turn to analyzing the presence of myoferlin in samples from numerous human tumor types available in an Ohio State tissue bank, which will allow them to compare protein levels in tumors to
clinical outcomes for the patients who provided the samples.
«Detecting genetic associations in cases of acute viral bronchiolitis is the first step toward the development of tests to predict the possible
clinical outcome for each patient diagnosed with the disease soon after arrival at the emergency room,» said Fernando Augusto de Lima Marson, a researcher at FCM - UNICAMP and one of the authors of the article.
The authors suggest that administering therapies targeting TP53 mutations may boost
clinical outcomes for patients with HPV - inactive tumors.
The MDS and AML Moon Shot is aimed at improving
clinical outcomes for patients with these diseases by focusing on the following fronts:
«What this study tells us is that we need a bigger trial to determine the difference — if any — in
clinical outcomes for these patients.»
Our offering of these advanced techniques provides improved
clinical outcomes for our patients.
Specifically, this NSC - mediated antibody delivery system has the potential to significantly improve
clinical outcome for patients with HER2 - overexpressing breast cancer.
«Our most striking finding is that BA leads to similar
clinical outcomes for patients with depression,» the study authors wrote, «but at a financial saving to clinical providers of 21 percent compared with the costs of provision of CBT.»
Through the affiliations with academic institutions, they are setting new standards in diagnostic and treatment protocols and achieving successful
clinical outcomes for their patients.
Not exact matches
Amarin's
clinical development program
for Vascepa includes a trial known as the REDUCE - IT cardiovascular
outcomes study, an 8,175 -
patient study commenced in 2011.
A search of Pubmed [a data base containing all medical journal articles]
for platelet rich plasma yields 6,811 articles, but less than 20 are
clinical studies evaluating
patient outcomes for orthopedic sports medicine conditions.
Our clinics are family friendly, providing care exclusively
for plagiocephaly
patients, and are staffed by highly trained, specialized
clinical staff that will work closely with you to achieve the best possible
outcome for your baby.
He is an expert in the use of systems - based methods to improve
patient outcomes, a leading researcher in use of large scale
clinical laboratories and electronic health records to improve the effectiveness and efficiency of care, and a nationally recognized thought leader in the very methods needed to transition to the future of lower - cost, more
patient - centered, health care
for the 21st century.
Future resources from the NCI Center
for Cancer Genomics (CCG), which oversees TCGA and other activities, will support more translationally focused research, including databases with genomic information on
clinical samples linked to
outcomes of their
patient donors.
«We believe these studies and
clinical trials that combine immunotherapy with chemotherapy are advancing efforts toward better
clinical care and more positive
outcomes for our
patients at CTCA,» said Dr. Vivek Khemka, Medical Oncologist, CTCA at Western and the WCLC study abstract's principal investigator and senior author.
In observational studies, researchers observe exposures and
outcomes for patients as they occur naturally in
clinical care or real life.
While randomized
clinical trials are the gold standard of
clinical research, such trials are not feasible
for testing anesthesia technique in joint replacement surgeries, because the low incidence
outcomes would require a huge number of
patients.
The next step, says Salem, will be to try to correlate these findings with
patient treatment
outcomes, initially as a retrospective, or backward looking study, and then hopefully design a forward looking
clinical trial to determine which treatments may be best
for patients with SBAs.
This is important because the proportion in which the de novo mutation is present in a
patient, as well as the type of cells in which it occurs, may not only determine the
clinical outcome of a disease
for the
patient, but also affect the risk of the parents having another child with the same disease in future pregnancies.
Professor Pincus and her team are now planning a larger
clinical trial to explore whether the combination of physiotherapy and psychology will improve
outcomes for patients and reduce treatment costs in the long term.
With survival rates improving
for ARDS
patients, understanding and improving their quality of life
outcomes is a
clinical and research priority, according to the study's principal investigator Samuel M. Brown, MD, MS, FASE, director of the Center
for Humanizing Critical Care at Intermountain Medical Center.
«This promising
clinical trial is the next step in a series of trials to identify new drugs that are fundamentally shifting the horizon — improving the
outcome for patients with advanced differentiated thyroid cancer.»
RELAX - AHF was a randomised, double blind controlled trial that evaluated the effects of a 48 - hour infusion of the intravenous drug, serelaxin, on
clinical outcomes in 1 161
patients admitted to hospital
for acute heart failure.
Principal Investigator John Morris, MD,
clinical co-leader of the Molecular Therapeutics and Diagnosis Program
for the CCC, co-leader of the UC Cancer Institute's Comprehensive Lung Cancer Program, professor in the division of hematology oncology at the UC College of Medicine and UC Health medical oncologist, says a number of antitumor vaccines have shown promise
for causing immune responses against tumor antigens to improve
patient outcomes.
Patients with CSA are good candidates
for the remede ® system which can improve their sleepiness, quality of life and potentially their
clinical outcomes.»
In a new study, a hospital surveillance program focusing on reducing the risks of sepsis, known as the two - stage
Clinical Decision Support (CDS) system, was found to reduce the risk of adverse
outcomes, such as death and hospice discharge
for sepsis
patients, by 30 % over the course of one year.
However, in analyses that accounted
for important
patient characteristics such as age, sex, comorbidities, and the reason
for hospitalization, the quality of care of the discharging hospital and SNF facility characteristics,
outcomes did not vary meaningfully across SNFs that differed in staffing ratings or their performance on
clinical measures related to pain or delirium.
When the researchers matched this data with
clinical outcomes for more than 4,600
patient specimens in medical databases, they found these subtypes were associated with different levels of disease progression.
«Emergency department crowding is clearly linked to worse
patient care and worse
outcomes, including higher mortality rates, higher rates of complications, and errors,» said Jesse M. Pines, M.B.A., M.D., director of the Office
for Clinical Practice Innovation, professor of emergency medicine and health policy at the GW School of Medicine and Health Sciences.
The researchers call
for more targeted studies to assess the
clinical outcomes of
patients who test positive
for metal sensitization.
To investigate, Csaba Kovesdy, MD (Memphis VA Medical Center and the University of Tennessee Health Science Center) and his colleagues examined information from the national VA research database and looked
for associations between blood pressure and various
clinical outcomes — coronary heart disease, stroke, kidney failure, and death — in more than 300,000
patients with CKD.
The results in this
clinical study will open up a new treatment modality
for glaucoma other than taking daily eye drops, and will greatly enhance
patient compliance and improve treatment
outcomes,» she said.
On the other hand
patients with DRB1 * 04:01 have a better
clinical outcome in the short - and long - term suggesting that human leukocyte antigen (HLA) analysis and screening
for SLA / LP antibodies should be integrated in the
clinical routine
for AIH diagnosis.
In order to show that the use of this system improves
patient outcomes, a
clinical trial at the Montreal Neurological Institute and Hospital will be launched
for patients with newly diagnosed and recurrent glioblastoma.
Imagine if a study proposed to hypnotize
patients, to tell them to believe all sorts of nonsense, and then to wake them up and leave them with those beliefs
for the rest of their lives because it was expected that the nonsense beliefs would produce positive
clinical outcomes.
Large
clinical trials testing therapies in
patients who test positive
for the standard biomarkers have generally «all failed to improve
outcomes.»
The
clinical trial will help to determine if the early microbubble intervention results in overall better
outcomes for patients.
In the paper «Having their say:
Patients» Perspectives and the Clinical Management of Diabetes,» Dr. Leonard Jack, Jr., Ph.D., M.Sc., Director of the Division of Community Health at the National Center for Chronic Disease and Health Promotion, and his co-authors Dr. Leandris C. Liburd, Ph.D., M.P.H., M.A. and Dr. Pattie Tucker, Dr.P.H., M.P.H. and R.N., propose that healthcare providers can offer more effective diabetes support to their patients by understanding the cultural perspectives that explain their health behavior, to promote adherence and improve health o
Patients» Perspectives and the
Clinical Management of Diabetes,» Dr. Leonard Jack, Jr., Ph.D., M.Sc., Director of the Division of Community Health at the National Center
for Chronic Disease and Health Promotion, and his co-authors Dr. Leandris C. Liburd, Ph.D., M.P.H., M.A. and Dr. Pattie Tucker, Dr.P.H., M.P.H. and R.N., propose that healthcare providers can offer more effective diabetes support to their
patients by understanding the cultural perspectives that explain their health behavior, to promote adherence and improve health o
patients by understanding the cultural perspectives that explain their health behavior, to promote adherence and improve health
outcomes.
«Involving the GP practices in the Salford Lung Study allowed the team to create an unsupervised environment
for the
patients, enabling important factors in usual
clinical care — such as adherence, frequency of dosing and persistence of good inhaler technique — to rightly influence the trial
outcomes.
The team attributed these cost savings to better
clinical outcomes for the DIMM clinic
patients, particularly their average glucose concentrations (measured as A1C).
The study wasn't designed to measure whether tumor profiling made a difference in how
patients fared, but «it nonetheless lays the groundwork
for more systematic study of the impact of genomics on
clinical practice and
patient outcomes,» the report said.
«We encourage
clinical trial participation in the hopes that we will improve the
outcome for our
patients with gynecologic malignancies.»
The researchers designed the study, called Effect of Remote Ischemic Preconditioning on
Clinical Outcomes in Coronary Artery Bypass Grafting Surgery (ERICCA), in an effort to find new ways to improve bypass outcomes for high - risk p
Outcomes in Coronary Artery Bypass Grafting Surgery (ERICCA), in an effort to find new ways to improve bypass
outcomes for high - risk p
outcomes for high - risk
patients.
However, our results showed that hospital - acquired anemia was associated with worse
clinical outcomes after leaving the hospital so it needs to be taken more seriously,» said senior author Dr. Ethan Halm, Director of UT Southwestern's Center for Patient - Centered Outcomes Research and Chief of the William T. and Gay F. Solomon Division of General Internal Medicine at UT South
outcomes after leaving the hospital so it needs to be taken more seriously,» said senior author Dr. Ethan Halm, Director of UT Southwestern's Center
for Patient - Centered
Outcomes Research and Chief of the William T. and Gay F. Solomon Division of General Internal Medicine at UT South
Outcomes Research and Chief of the William T. and Gay F. Solomon Division of General Internal Medicine at UT Southwestern.
Each chart was reviewed
for patient demographics, presenting symptoms and signs, tumor location and size, imaging findings, extent of surgical resection, histopathological findings, radiographic follow - up, tumor recurrence, and
clinical outcome.
TORONTO, May 12, 2016 — A new Canadian study focusing on caregiver
outcomes of critically ill
patients reveals that caregivers of intensive care unit (ICU) survivors, who have received mechanical ventilation
for a minimum of seven days, are at a high risk of developing
clinical depression persisting up to one year after discharge.
In the $ 1.47 million, four - year grant called â $ œBiomarkers of Ischemic
Outcomes in Intracranial Stenosisâ $ (BIOSIS), Emory researchers are analyzing blood samples from 451
patients from around the country who were enrolled in a study known as SAMMPRIS (Stenting and Aggressive Medical Management
for Preventing Recurrent stroke in Intracranial Stenosis), the first randomized, multicenter
clinical trial designed to test whether stenting intracranial arteries would prevent recurrent stroke.
While translational research has traditionally moved basic immunology knowledge forward into
clinical application, varying
clinical presentations of human immune - related disease processes, as well as variability in therapeutic
outcomes, have provided opportunities
for discovery of novel mechanistic hypotheses directly from
patients.
GeneAssess is currently validating these results with
clinical samples from cancer
patients and examining FRY's correlation and association with these samples
for diagnostics and
outcome predictions.