Sentences with phrase «clinical outcomes of treatment»

Not exact matches

Access to medication and treatments Diabetes UK believes that people with diabetes should have equal access to the best diabetes care and health outcomes available on the basis of clinical need and appropriateness, not on their or the NHS's ability to pay.

Placebos are used to help accurately measure clinical responses / outcomes when studying the effects of medications, therapies, and other treatments.

A late - breaking clinical trial, known as the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, to be presented at the American Heart Association (AHA) Scientific Sessions, November 18, 2013, demonstrates that spironolactone did not reduce the primary outcome of cardiovascular death, heart failure hospitalization, nor surviving a cardiac arrest in patients with heart failure and preserved ejection fraction (pump function).

Besides working at IBM's Thomas J. Watson Research Center in Yorktown Heights, New York, Meyer heads something called the DREAM challenges, contests that ask teams of computer scientists to solve outstanding biomedical problems, such as predicting the outcome of prostate cancer treatment based on clinical variables or detecting breast cancer from mammogram data.

A first - of - its - kind literature review published in the September issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists ® (ASA ®), suggests although a majority of studies report positive outcomes, there is currently insufficient evidence to support the clinical use of antidepressants for the treatment of postoperative pain.

Mankoff and his colleagues argue that making a strong clinical case for these new imaging techniques will mean demonstrating their ability to improve traditional treatment outcomes such as progression - free survival and quality of life.

«Insomnia affects empathy in health care workers which can lead to adverse clinical outcomes,» said lead author Venkatesh Basappa Krishnamurthy, MD, assistant professor, Sleep Research and Treatment Center, department of psychiatry, Penn State College of Medicine in Hershey, Pa..

Professor Pincus and her team are now planning a larger clinical trial to explore whether the combination of physiotherapy and psychology will improve outcomes for patients and reduce treatment costs in the long term.

The authors suggest minimal residual disease status may be a marker of long - term survival outcome and the assessment of minimal residual disease status after treatment should be considered as an end - point in clinical trials.

The study, Developing an Interventional Stroke Service: Improving Clinical Outcomes and Reducing Cost and Delivering Great Cost Savings Benefits to Health Economy, conducted at the University Hospital of North Midlands, Stoke - on - Trent, U.K., found that mechanical thrombectomy (the use of a device to retrieve a clot from the vessel) in the treatment of stroke reduced the average stroke patient's hospital stay to 14 days when compared to previously recorded 90 days.

«Once additional key clinical and genetic factors are identified, infants who are determined to have a low risk of requiring medication can be sent home without prolonged monitoring, and those who are predicted to have a difficult clinical course can be started on more aggressive treatment earlier, which will lead to shorter hospitalizations and improved outcomes.»

«Using an algorithm based on genetic testing to guide treatment is sustainable and associated with better clinical outcomes in a real - world clinical practice, although it is difficult to consistently maintain,» said Craig R. Lee, Pharm.D., Ph.D., F.A.H.A., associate professor of pharmacy at the University of North Carolina at Chapel Hill Eshelman School of Pharmacy.

«Since several BACE1 inhibitors are currently being evaluated in clinical phase 3 trials for the treatment of Alzheimer's disease, the identification of potential side effects will be of great importance to ensure a positive clinical outcome,» said Dr. Jochen Herms, a Professor of translational brain research at Ludwig - Maximilians - University Munich.

They also summarise the outcome of clinical trials that have investigated the use of mesenchymal stem cells in the treatment of a number of inflammatory, degenerative and immune - mediated diseases of cats.

«TOPCAT is the first randomized, double - blind trial to assess the effect of a treatment - spironolactone - on clinical outcomes in this patient demographic.»

«While the present report suggests that optimal outcome measures for FXS are not yet fully developed, the recent failures of clinical trials in the FXS treatment field represent an opportunity to implement novel study designs and methodologies,» concludes Budimirovic.

Tryfonidis et al. discuss perspectives and future directions for the management of locally advanced breast cancer in Nature Reviews Clinical Oncology, and they see a need for not only standardizing treatment for this disease, but also for developing new therapies that could substantially improve outcome.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

This study was presented at the Featured Clinical Research Session I: Two - year Outcomes of Surgical Treatment of Moderate Ischemic Mitral Regurgitation: A Randomized Clinical Trial from The Cardiothoracic Surgical Trials Network The Moderate Ischemic Mitral Regurgitation trial was supported by a cooperative agreement (U01 HL088942) funded by the National Heart Lung and Blood Institute, the National Institutes of Neurological Disorders and Stroke of the National Institutes of Health (NIH), Bethesda, MD, and the Canadian Institutes of Health Research.

Conducted by Prof Rose McGready and Assoc. Prof Daniel Henry Paris from the Shoklo Malaria Research Unit (SMRU) in Mae Sot, Thailand, and the Mahidol Oxford Research Unit (MORU) in Bangkok, affiliated to Oxford University, UK, in collaboration with Prof John Antony Jude Prakash of the Dept. of Clinical Microbiology, Christian Medical College, Vellore, India, the study, «Pregnancy outcome in relation to treatment of Murine typhus and Scrub typhus infection: a fever cohort and a case series analysis,» will be published in the November 20th, 2014 issue of PLOS Neglected Tropical Diseases.

Clinical trials found that it is safe to regularly infuse brain and lung cancer patients with 800 — 1000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments.

Writing in a linked Comment, Professor Philip Cowen, MRC Clinical Scientist, University of Oxford, Oxford, UK, says: «The key observation that might eventually justify the use of a drug like psilocybin in treatment - resistant depression is demonstration of sustained benefit in patients who previously have experienced years of symptoms despite conventional treatments, which makes longer - term outcomes particularly important.

The studies rigorously assessed the clinical impact of omega - 3 fish oil treatment on outcomes such as heart attacks, strokes, atrial fibrillation (a heart rhythm disorder) and others.

It corroborates the findings of another NIAID - funded study demonstrating that TMP - SMX treatment resulted in better clinical outcomes than placebo for MRSA skin abscesses, and also upholds other findings that both clindamycin and TMP - SMX are equally beneficial in treating MRSA skin infections.

The team is currently pursuing further studies of the impact of Part D cost - sharing policies in different disease areas, and hopes ultimately to get a better understanding not only of changes in drug access but also of the long range clinical outcomes and costs associated with any delays or interruptions in treatment.

The traditional approach, in which researchers studied the clinical outcomes of an intervention without assessing whether the intervention altered a well - defined target, established current, well - accepted treatments such as exposure therapy and dialectical behavior therapy.

Using the large patient group in the ProTECT III trial, the researchers hope to validate promising TBI biomarkers as predictors of clinical outcome and also evaluate the relationship between progesterone treatment, biomarker levels and outcome.

Head and neck cancers are particularly unique and complex, requiring a personalized treatment plan for optimal clinical, quality - of - life and cosmetic outcomes.

BACKGROUND Whether endovascular stroke treatment improves clinical outcomes is unclear because of the paucity of data from randomised placebo - controlled trials.

«Our study found that apalutamide treatment markedly improved metastasis - free survival and other clinical outcomes in men with castration - resistant prostate cancers and no detectable metastases,» says Matthew Smith, MD, PhD, of the MGH Cancer Center, corresponding author of the NEJM report.

Penn's multidisciplinary approach to the diagnosis and treatment of mesothelioma provides better outcomes and gives you access to the most advanced treatment, surgical techniques and clinical trials.

«PROs supplement clinical outcomes and provide a holistic understanding of patient experience and treatment effectiveness, and help inform therapeutic choices, disease management practices, reimbursement decisions, and health policy,» said Dirk Schadendorf, MD, director of the department of dermatology at the University Hospital Essen in Essen, Germany.

To help combat this problem, this Center of Excellence harnesses expertise from research and clinical areas of Cleveland Clinic to understand the causes of colon cancer metastasis and to improve prevention, treatment and, ultimately, patient outcomes.

However, a proportion of patients remain ill [12, 13], and delayed treatment is associated with negative clinical outcomes [14, 15].

Clinical pathogen sequencing has been demonstrated to have a positive outcome on treatment of patients with unknown bacterial infection.

They suggest that age at onset of ambulation could be a primary outcome measure in clinical trials involving treatment in early infancy.

These endothelialized grafts may represent a promising treatment strategy for improving the clinical outcome of small - caliber vascular grafts in cardiac bypass surgeries.

Continued intractable seizure activity in an infant will impact on long - term cognitive and behavioural outcomes, with considerable cost implications for health services due to need for regular clinical review, hospital treatment, medications and support of other therapies.

Information technology and new concepts in clinical outcomes assessment are particularly well - suited to evaluating the effectiveness of naturopathic treatment protocols and are being used in research, both at naturopathic medical schools and in the offices of practicing physicians.

Several pieces of evidence demonstrate the efficacy of hypnosis: «the addition of hypnosis substantially enhanced treatment outcome» according to the Journal Of Consulting And Clinical Psychology in which six studies on weight loss were investigateof evidence demonstrate the efficacy of hypnosis: «the addition of hypnosis substantially enhanced treatment outcome» according to the Journal Of Consulting And Clinical Psychology in which six studies on weight loss were investigateof hypnosis: «the addition of hypnosis substantially enhanced treatment outcome» according to the Journal Of Consulting And Clinical Psychology in which six studies on weight loss were investigateof hypnosis substantially enhanced treatment outcome» according to the Journal Of Consulting And Clinical Psychology in which six studies on weight loss were investigateOf Consulting And Clinical Psychology in which six studies on weight loss were investigated.

Astragalus: As well as being adaptogenic, tonic and immune stimulating it is also cardiotonic and hypotensive with clinical trials reporting favorable outcomes in the treatment of cardiac problems.

Clinical Outcomes of a Diagnostic and Treatment Protocol in Allergy / sensitivity Patients Alternative Medicine Review 2001 (Apr); 6 (2): 188 — 202 ~ FULL TEXT This level II outcome study was conducted to examine the efficacy and toxicity of a diagnostic and treatment protocol using electrodermal screening (EDS) in allergy / sensitivity Treatment Protocol in Allergy / sensitivity Patients Alternative Medicine Review 2001 (Apr); 6 (2): 188 — 202 ~ FULL TEXT This level II outcome study was conducted to examine the efficacy and toxicity of a diagnostic and treatment protocol using electrodermal screening (EDS) in allergy / sensitivity treatment protocol using electrodermal screening (EDS) in allergy / sensitivity patients.

Detailed Information The GI Pathogen Profile, using the FilmArray multiplex PCR system, tests for 22 Viruses, parasites, and bacteria, and offers new opportunities for the rapid, accurate diagnosis and prompt treatment of diarrheal illnesses which can improve patient outcomes and clinical success.

Medical records of dogs diagnosed with schistosomiasis from 2000 to 2009 were reviewed, and information extracted included signalment, history, clinical signs, diagnostic test results, treatment, and outcome.

Acupuncture is part of Traditional Chinese Veterinary Medicine and can be readily integrated into conventional treatment modalities to optimize clinical outcomes.

In concurrent studies, the team will examine the gene expression profile of subsets of patients with different clinical outcomes to provide further insight into why certain dogs have more aggressive B - CLL and to identify possible drug targetable pathways to improve the treatment for this cancer.

The prognosis for long - term outcome among PL patients in general, regardless of treatment option, worsens the older the patient is at onset and as the grade of luxation and severity of clinical signs increase.17

Treatment in Dogs: The extent of the preadulticide evaluation will vary depending on the clinical status of the patient and the likelihood of coexisting diseases that may affect the outcome of tTreatment in Dogs: The extent of the preadulticide evaluation will vary depending on the clinical status of the patient and the likelihood of coexisting diseases that may affect the outcome of treatmenttreatment.

The addition of acupuncture to an established treatment regimen can improve clinical outcome.

Understanding the typical clinical presentations and initial treatment of common emergencies, as well as having a plan in place for when such cases occur, is critical for successful outcomes.