Sentences with phrase «clinical phase of development»

Allan Robins, Ph.D., Senior Vice President of Science and Technology, will review recent progress with the company's VC - 01 ™ product candidate for the treatment of type 1 diabetes, which entered the clinical phase of development late last year.

Dr. Brandon will review recent progress with the company's VC - 01 ™ product candidate for the treatment of type 1 diabetes, which recently entered the clinical phase of development.

Dr. Laikind will review recent progress with the company's VC - 01 ™ islet replacement product candidate for the treatment of type 1 diabetes, which recently entered the clinical phase of development.

Not exact matches

Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the treatment of ocular melanoma, a rare and life - threatening disease.

This includes a stem cell research centre, a network of drug discovery institutes and a # 20 million global clinical development fund dedicated to supporting Phase I and II clinical trials; and a # 2 million collaboration between University of Cambridge and University College London that will use donated cells from people with Alzheimer's to test potential new treatments

For example, you might make a list of 20 or 30 companies, all with cancer drugs in Phase II of clinical development.

But highly trained life scientists will still be needed for such tasks as late - stage development (ensuring smooth implementation of final phase (III and IV) clinical trials) as well as compliance with regulatory demands (so - called commissioning and validation specialists), according to Croonen.

Last month, Biopure launched a revamped clinical development program, emphasizing testing in Europe, with three phase II clinical trials planned for 2008 to study the impact of its product on heart attack patients, chemotherapy patients with anemia and the terminally ill.

The documentation ranges across the whole spectrum of drug development: Investigators» brochures provide information on all that is currently known about the medicine and so need periodic updating; accurate and concise protocols are required to ensure that trials are performed effectively; clinical trial reports (generally from phase II and III studies) present the information gathered from the trials; higher level documents provide summaries of efficacy and safety data from clinical trial programmes; expert reports provide critical interpretation of the results; and response documents clarify any points that are not clear to the regulatory agencies or provide additional analyses or supporting data for any items of concern.

However, RA professionals are increasingly involved with products during the research and development phases, in the design and monitoring of clinical studies, marketing, advertising, and communications.

Her research at Stanford University has contributed to the development of a small molecule peptide that is currently in Phase IIA clinical trials for AD.

Development of a second CETP inhibitor, dalcetrapib, was stopped when a phase 2 clinical trial found the drug to be ineffective.

The authors believe that the incorporation of such a blood test into routine clinical practice could provide a prime opportunity for intervention during the pre-cancerous phase before the development of pancreatic malignancy.

The phase in the development of a new treatment where clinical trials are conducted using many patients, to determine whether the treatment is effective

P - BCMA - 101 is Poseida's lead CAR - T therapy currently in Phase 1 clinical development for the treatment of multiple myeloma.

Research Interests: Clinical pharmacology of anticancer agents; early phase drug development; drug tolerability in cancer patients with HIV / AIDS; drug tolerability in cancer patients with organ dysfunction; blood - brain barrier penetration of drugs.

She is CEO of PsychoGenics Inc., a profitable preclinical CNS service company, CEO of PGI Drug Discovery LLC, a company engaged in psychiatric drug discovery with three partnered Phase II clinical programs and Adjunct Associate Professor of Neuroscience at Mount Sinai School of Medicine, Dr. Leahy has more than 25 years of experience in drug discovery, clinical develop and business development for pharmaceutical and biotechnology companies, including extensive knowledge of technology assessment, licensing, mergers and acquisitions, and strategic planning.

GenIbet's core activity is the manufacture and supply of materials for use in early stage drug development, pre-clinical studies and cGMP manufacturing from Phase I to Phase III clinical trials.

Once this development culminated in the product of the successive phases of clinical trials, for a provision of patients.

The company's lead product is for the personalized treatment of advanced renal cell carcinoma and is in phase III clinical development.

Reykjavik, ICELAND, December 17, 2004 — deCODE genetics (Nasdaq: DCGN) today announced the signing of an agreement under which it will conduct a Phase II information - rich clinical trial next year of a third - party compound as part of a drug development program in asthma.

We have completed the active phase of a Phase 1 trial of a Vaxwave ® - based vaccine against cytomegalovirus (CMV) and are finalizing clinical development plans for TheraT ® in Human Papilloma Virus (HPV)- related head and neck canphase of a Phase 1 trial of a Vaxwave ® - based vaccine against cytomegalovirus (CMV) and are finalizing clinical development plans for TheraT ® in Human Papilloma Virus (HPV)- related head and neck canPhase 1 trial of a Vaxwave ® - based vaccine against cytomegalovirus (CMV) and are finalizing clinical development plans for TheraT ® in Human Papilloma Virus (HPV)- related head and neck cancers.

Asterias has received a Strategic Partnerships Award grant from the California Institute for Regenerative Medicine, which provides $ 14.3 million of non-dilutive funding for the Phase 1 / 2a clinical trial and other product development activities for AST - OPC1.

A concentrated source of information on cell therapies spanning the different stages of development: including research, pre-clinical, clinical and marketed phases, being pursued by both non-profit organizations (NPO) and industries.

Table 1: Selection, Design & Construction of HSV - based Oncolytic Viruses Table 2: Selection, Design & Construction of Adenovirus - based Oncolytic Viruses Table 3: Selection, Design & Construction of Vaccinia Virus - based Oncolytic Viruses Table 4: Selection, Design & Construction of Vesicular Stomatitis Virus - based Oncolytic Viruses Table 5: Selection, Design & Construction of Newcastle Disease Virus - based Oncolytic Viruses Table 6: Selection, Design & Construction of Various Virus - based Oncolytic Viruses Table 7: Current Company - Sponsored Clinical Trials of T - Vec Table 8: Clinical Trials of ColoAd1 Table 9: Clinical Trials with JX - 594 Table 10: Clinical Trials with GL - ONC1 Table 11: Clinical Trials of CAVATAK (CVA21) Table 12: Clinical Trials with MV - NIS Table 13: Overview of Oncolytic Viruses by Development Phase & Virus Family Table 14: Profile of Approved and Marketed Oncolytic Viruses Table 15: Pivotal Study Design of Oncolytic Viruses in Late Stage Development Based on Previous Clinical Results Table 16: Approved Indications of Immune Checkpoint Inhibitors Table 17: Active Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 18: Planned Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 19: Active or Planned Clinical Studies of Oncolytic Viruses in Combination with Other Anti-Cancer Therapeutics Table 20: Pattern of Transgenes in Oncolytic Viruses in Relation to Development Phase Tables 21a and 21b: Indications and Frquency and Way of Administration of Oncolytic Viruses in Active and / or Positive Completed Clinical Studies Table 22: Small and Medium Pharma & Biotech as Partner for Regional Co-Development of Oncolytic Viruses Table 23: Immuno - Oncology Portfolio of Major Pharma & Biotech with Interest in Oncolytic Viruses Table 24: Interests of Major Pharma & Biotech in Oncolytic Viruses Table 25: First Generation Oncology Virus Companies and their Sources of Technology Table 26: Second Generation Oncology Virus Companies and their Sources of Technology Table 27: Third Generation Oncology Virus Companies and their Sources of Technology Table 28: Fourth Generation Oncology Virus Companies and their Sources of Technology Table 29: Grants, Credits & Donations Table 30: Financing by Venture Capital, Private Equity and Other Private Placements Table 31: Collaboration & Licensing Agreements Table 32: Companies Listed on Stock Exchange & Offerings Table 33: Mergers & Acquisitions

Finally, the plans for the future development of the vaccine and the next steps to phase II clinical trial were presented.

We believe this finding will assist us in designing the next phase of clinical development, in which DG031 will be studied for the prevention of heart attack.»

Texas Children's Cancer Center is a member of the COG Phase I Consortium, a small and select group of institutions that administer Phase I clinical trials of drugs in early development.

The clinical biostatistics team has strong connection with the Biometry department (Head A. Savignoni), the early phase clinical trial and precision medicine unit where patients are treated with drugs in development (Head C. Le Tourneau), the translational research department in particular the Circulating Tumor Biomarkers laboratory (Charlotte Proudhon), and of course the other teams of the U900.

The scientific goal of the Developmental Cancer Therapeutics Program is to discover and characterize unique agents and pathways that will impact the development of more effective cancer therapies and to translate these discoveries into clinical applications by using proof - of - principle, early phase clinical and correlative science studies.

Overall, SR - Tiget represents a multi-disciplinary research environment, which provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant preclinical models to evaluate their efficacy and safety, as well as competence in conducting early phase clinical trials.

deCODE genetics (Nasdaq: DCGN) today announced that it has begun enrolling patients in its Phase I clinical development program for DG051, the company's follow - on developmental compound for the prevention of heart attack.

Reykjavik, ICELAND, December 17, 2004 — deCODE genetics (Nasdaq: DCGN) today announced the signing of an agreement under which it will conduct a Phase II information - rich clinical trial next year of a third - party compound as part of a drug development program in...

Recent clinical studies support the development of DG041 as an effective anti-platelet that does not increase bleeding risk deCODE genetics (Nasdaq: DCGN) today announced progress in the development of DG041, the company's Phase II developmental compound for the...

Translational medicine is the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to improve disease understanding, confidence in human drug targets and increase confidence in drug candidates, understand the therapeutic index in humans, enhance cost - effective decision making in exploratory development and increase phase II success.

Essentially, Roche has committed to paying Isis $ 30 million for the development of its Huntington's disease drugs and the first «phase 1» clinical trial in patients.

The positive results from the two phase III studies of ipilimumab were made possible in part through the evolution of the clinical science, which is based on new models of academic - industry partnership to advance immunotherapy development.

GENYO is the first national centre devoted to genomics that integrates the Public Administration, the University and the biotechnology and pharmaceutical business sector, which would allow the integration of research in all its phases, from the generation of knowledge to its development in clinical and pharmaceutical applications, the development of new projects and services for the prevention, diagnosis and treatment of diseases associated to human genetic variability, such a cancer and rare diseases, diabetes, hypertension or degenerative diseases, among others.

Lilly Halts Development of Semagacestat for Alzheimer's Disease Based on Preliminary Results of Phase III Clinical Trials.

That's when I started working as an Associate Clinical Project Manager in the Late Phase area of Clinical Development.

Approved programs demonstrate responsibility for the quality of candidates by ensuring that development of candidate quality is the goal of educator preparation in all phases of the program — from recruitment, at admission, through the progression of courses and clinical experiences — and in decisions that program completers are prepared to be effective educators and are recommended for certification.

BioMS is in a clinical development phase with a phase - two and a couple of phase - three clinical trials going on, which means that there are clinical - trial agreements, indemnification agreements, budget - amendment agreements, as well as research and development contracts with outside agencies and those with outside consultants.

Practical knowledge of GMP and an ability to apply sound judgment and decision - making skills (risk based and appropriate for the phase of clinical development) in order to evaluate product release.

Worked in a Phase I / II clinical trials research laboratory that focuses on the development of antigen - specific cytotoxic T - lymphocytes for adoptive cellular immune therapies in children and adults

Past successes have included development and clinical characterization of biologics (anti-IL10 and 23 neutralizing antibodies - Phase III) along with small molecule antagonists (HCV - «Boceprevir» and BACE (Phase I - III clinical development)-RRB-.

Summary: This project involved development and testing thoroughly the concepts of phase 1 of Clinical Acces...

Areas of Clinical Interest: Women's Issues, Adolescent & Child Development, Disordered Eating Issues, Depression, Anxiety, College Students, Creative Individuals, Phase of Life / Adjustment Transitions, Cultural Issues.

Family Healing, coauthored with Michael Nichols, blends vignettes from Minuchin's personal history with clinical cases to illustrate his understanding and treatment of families throughout various phases of family development.