In conclusion, histone modifier genes indicate
clinical progression of PTCL - NOS and may represent a group of actionable biomarkers of this disease subtype.
Lower plasma ApoA1 levels were associated with an increased risk of
clinical progression in APOE ɛ 4 carriers with SCD (HR 5.0 (1.3 — 18.9)-RRB-.
Our finding of similarity in
clinical progression between human patients and Huntington's disease monkeys suggests monkeys could become a preclinical, large animal model for the development of new treatments.»
Conclusion: Higher CSF and lower plasma ApoA1 levels were associated with an increased risk of
clinical progression in APOE ɛ 4 carriers with SCD; suggesting that ApoA1 may be involved in the earliest stages of AD.
Proprietary workflows and cutting - edge technologies enable quantification of low - level mutations during treatment as well as detection of cancer recurrence, often prior to
clinical progression.
But Virginia Tech researchers found that modifying the shape of IRAK - M, a protein that controls inflammation, can significantly reduce
the clinical progression of both diseases in pre-clinical animal models.
One standard deviation increase of CSF ApoA1 was associated with a 30 % increased risk of
clinical progression (hazard ratio (HR)(95 % CI) = 1.3 (1.0 — 1.6)-RRB-.
We used Cox proportional hazard models to investigate relations between CSF and plasma ApoA1 concentrations and
clinical progression, defined as progression to MCI or AD for SCD, and progression to AD for MCI.
B - cell chronic lymphocytic leukemia (B - CLL) is a common cancer in dogs, but little is known about the disease, including
its clinical progression and survival expectations for patients.
Secondary infection with yeast and bacteria are quite common in cases of canine and feline mange, leading to a cascade of
clinical progression that can become very severe and uncomfortable for the pet.
Notoedric mange in cats presents very much like sarcoptic mange in dogs, with
a clinical progression very similar to that of sarcoptic mage in dogs.
The skin lesions have a similar age of onset and
clinical progression, but with dermatomyositis, erythematous plaques or vesicles can not be induced in normal skin by applying mild friction.
Kadon P.F., et al., «Topical KINOSTAT ™ ameliorates
the clinical progression of cataracts in dogs with diabetes mellitus» Vet Ophthalmol Nov. 2010; 13 (6): 363 - 8.