As highlighted in the final print issue of Genome Technology, investigators leading
clinical sequencing efforts have faced ethical dilemmas already, such as the return of genetic information to family members in the event that a patient dies.
It will focus its initial
clinical sequencing efforts on cancer, teaming up with the Moores Cancer Center at the University of California, San Diego to sequence the genomes of every patient who is treated there, as well as perform a full genome sequence on their tumors.
Not exact matches
Through its
effort to develop, produce and distribute a suite of genome RMs, the consortium is providing medical and research laboratories worldwide with the tools they need to advance
clinical applications of whole genome
sequencing, and the FDA with the ability to conduct science - based regulatory oversight of the technology.
Topics that will be explored include: • Cellular and developmental origins of pediatric cancer • Key findings of pan-cancer analysis
efforts • Computational pipelines to analyze large - scale
sequencing data • Opportunities for leveraging existing cancer genomics datasets • Strategies for integrative analysis of germline and somatic variants • Correlation of germline / somatic variation to
clinical features such as tumor subtype.