Sentences with phrase «clinical stage»

• UroGen Pharma, an Israel - based clinical stage biopharmaceutical company, announced terms for its IPO.

Inflammatory and cardiac biomarkers are differentially expressed in clinical stages of Chagas disease.

• Apexian Pharmaceuticals, an Indiana - based clinical stage biotechnology company, raised Series A funding of an undisclosed amount.

• Arsanis, a Waltham, Mass. - based clinical stage biopharmaceutical company focused on monoclonal antibodies, filed for an $ 58 million IPO.

SEER - Medicare does not provide clinical stage for surgical patients.

The finding suggests that treatment strategies for Huntington's that aim to shut off the huntingtin gene in adults — now in early clinical stages — could be safe.

Patients were significantly more likely to be diagnosed with clinical stage 2b (p = 0.001) or stage 2c - 3a PCa (p = 0.027).

Spark Therapeutics Gene therapy clinical stage company, spin out of Children's Hospital of Philadelphia, founded in 2013.

• PROCEPT BioRobotics, a Redwood Shores, Calif. - based clinical stage medical device company, raised $ 118 million in funding.

Participants in the study included 588 men diagnosed with intermediate risk prostate cancer (i.e., clinical stage T1c - T2b) and enrolled in the trial between 2003 and 2012.

Lower clinical stage (cT1 - cT2a) indicates a tumor that has not spread.

Compared to patients with low - risk disease, those with intermediate - risk cancer (PSA > 10ng / ml or Gleason score 7 or clinical stage T2b / 2c) had a nearly four-fold higher chance of dying from prostate cancer within 15 years.

The board has approved $ 50 million in spending to support the first 6 months under the new funding mechanism, which will be available to «late preclinical» and clinical stage projects.

The racially diverse study sample consisted of two groups: 89 patients diagnosed with low risk prostate cancer (clinical stage T1 - T2a, biopsy Gleason score 6 or less, and prostate specific antigen less than 10 ng / ml), who initially underwent AS, and 420 patients without cancer who had a negative prostate needle biopsy.

«With breakthrough technology, clinical stage product candidates, an extensive intellectual property estate, and a strong and dedicated team, ViaCyte has all the pieces to advance a transformative new life - saving approach that could help hundreds of thousands of people with high - risk type 1 diabetes around the world.»

Unum Therapeutics Cellular immunotherapeutic, clinical stage startup from Cambridge (MA), founded last year.

In 2005, Dan co-founded and served as President and CEO of Inviragen Inc., which he transformed from a virtual start - up to a global clinical stage company with sites in Colorado, Wisconsin and Singapore and translated two vaccines from the research bench to human clinical trials, including one for dengue fever.

Its product line encompasses three clinical stage protein therapeutic candidates - Sotatercept, ACE - 536 and Dalantercept.

Subcortical volumetric differences between clinical stages of young people with affective and psychotic disorders.

• Clementia Pharmaceuticals, a Montreal, Canada - based clinical stage biopharmaceutical company focused on bone diseases, filed for an IPO to raise $ 115 million.

• Eureka Therapeutics Inc, an Emeryville, Calif. - based clinical stage biotechnology focused on treating solid tumors, raised $ 60 million in Series D funding.

Adult mice don't need the gene that, when mutated in humans, causes the inherited neurodegenerative disorder Huntington's disease. The finding suggests that treatment strategies for Huntington's that aim to shut off the huntingtin gene in adults — now in early clinical stages — could be safe.

Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease

• Arsanis, a Waltham, Mass. - based clinical stage biopharmaceutical company focused on monoclonal antibodies, raised $ 40 million in an offering of 4 million shares at $ 10 a piece, below its $ 15 to $ 17 range.

SEATTLE, April 23, 2018 (GLOBE NEWSWIRE)-- Nohla Therapeutics Inc. (Nohla), a clinical stage biopharmaceutical company focused on the development of universal, off - the - shelf cell therapies to treat cancer and other critical diseases, today announced the hiring of Gary Christianson, PE, as the company's new Chief Operating Officer (COO).

CalciMedica is a privately - held, clinical stage biopharmaceutical company focused on CRAC channel drug discovery and development for the treatment of acute and chronic inflammatory diseases.

Sierra Oncology, Inc., a clinical stage drug development company focused on advancing next - generation DNA damage response therapeutics for the treatment of patients with cancer, went public near $ 29 in July 2015, then began a downtrend that continued through a June 2017 all - time low of $ 1.10.

Minoryx is a clinical stage biotech company leading the development of new therapies for X-ALD and other inborn errors of metabolism, a group of rare diseases of genetic origin with a high unmet medical need.

Research Triangle Park, NC — May 24, 2017 — Pappas Capital, a life science venture capital firm, announced today that its new fund, Pappas Ventures V, recently invested in OrphoMed, a clinical stage company that is developing best - in - class therapies for treatment of inadequately - controlled gastrointestinal disorders.

Kite Pharma is highly speculative since it is a clinical stage company that is not yet profitable.

Maastricht, The Netherlands, 28 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, today announced that it secured a $ 2.5...

Maastricht, The Netherlands, 24 October 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, has appointed Dr. Istvan Udvaros as its Chief...

Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, announced today that it has begun a Phase 1b...

Given that it's been bringing three to five new therapies into the clinical stage each and every year, I'd opine that it's working like a charm.

They gauged aggressiveness using the results of the patients» prostate cancer - specific antigen, or PSA, tests, as well as the clinical stage of their cancer and Gleason grade.

Moderna is a clinical stage pioneer of messenger RNA (mRNA) therapeutics and vaccines, an entirely new drug technology that directs the body's cells to produce intracellular or secreted proteins.

6) and clinical stage (cT1b to cT4).

Dr. Bot's background is in theoretical and experimental immunology, cancer research, and biomolecule and small molecule drug development, spanning preclinical and clinical stages.

«Cancer is like a person's thumbprint; each person's cancer is uniquely theirs,» says Bill Hearl, CEO of Immunomic Therapeutics, a clinical stage biotechnology company developing a nucleic acid immunotherapy platform with the potential to treat cancer, allergies and animal health issues.

Therefore, much more study on the efficacy and safety of statins, especially in the young, is needed before they reach the clinical stage for TD and ACH treatment.»