Sentences with phrase «clinical studies point»

Not exact matches

The company points to a simple resource allocation problem that's hindered the most effective patient care: the fact that it is physically impossible for oncologists to keep track of every study, every clinical trial, and every breakthrough in the wildly stratified world of cancer research.

[31] Critics also point out that even the $ 6 million attributed to the reduction of mercury emissions is likely an exaggeration because the EPA has ignored clinical studies that demonstrate the human body's ability to protect itself against mercury.

Attendees will learn through case studies how a PBM can engage all care stakeholders collaboratively - prescribers at the point of care (PoC), pharmacists at the point of sale (PoS), patients, and payers» clinical / pharmacy staff to reduce overall pharmacy costs and avoidable drug — impacted medical costs while improving compliance and patients» quality of life.

Attendees will learn through case studies how a PBM can engage all care stakeholders collaboratively — prescribers at the point of care (PoC), pharmacists at the point of sale (PoS), patients, and payers» clinical / pharmacy staff to reduce overall pharmacy costs and avoidable drug - impacted medical costs while improving compliance and patients» quality of life.

The thousands of clinical studies that have looked into the effects of diet on cancer point to these factors being most important for cancer risk reduction:

These virtual results are based on the actual data points derived from StriVectin's extensive clinical studies for StriVectin - SD ™ Intensive Concentrate for Stretch Marks & Wrinkles and StriVectin - SD ™ Eye Concentrate for Wrinkles.

Studies were included if: (a) they were RCTs, (b) the population comprised parents / carers of children up to the age of 18 where at least 50 % had a conduct problem (defined using objective clinical criteria, the clinical cut - off point on a well validated behaviour scale or informal diagnostic criteria), (c) the intervention was a structured, repeatable (manualised) parenting programme (any theoretical basis, setting or mode of delivery) and (d) there was at least one standardised outcome measuring child behaviour.

Dr. Robert Cantu, one of the world's leading experts on head trauma in sport and a clinical professor of neurosurgery at Boston University School of Medicine, has pointed to studies showing at least 30 percent of concussions in soccer come from the act of heading the ball, sometimes through direct contact with the ball but more significantly when the head smashes into another player or the ground.

«More long - term studies are required to ensure that the results can be confidently translated into clinical practice, however, the science at this point in time is compelling and should not be ignored.»

«We have now found a potential mechanism, and at this point in our research, we need to test human participants in a blinded, placebo controlled clinical study — the same technique we used to study the behavioral effects of acupuncture in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.

Now a University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining this failure and offering a possible strategy for the use of retinoic acid or other retinoids against some breast cancers: Because early clinical trials are often offered to patients who have already tried other more established therapies, breast cancer cells may have been pushed past an important tipping point that offers retinoic acid resistance.

Plus, he points to two clinical studies that have shown that the fever - reducer acetaminophen — commonly known as Tylenol — decreased fever - associated birth defects, and he suggests that doctors and patients consider the drug's use to treat fevers early in pregnancy.

The documentation ranges across the whole spectrum of drug development: Investigators» brochures provide information on all that is currently known about the medicine and so need periodic updating; accurate and concise protocols are required to ensure that trials are performed effectively; clinical trial reports (generally from phase II and III studies) present the information gathered from the trials; higher level documents provide summaries of efficacy and safety data from clinical trial programmes; expert reports provide critical interpretation of the results; and response documents clarify any points that are not clear to the regulatory agencies or provide additional analyses or supporting data for any items of concern.

«As a result, drugs are approved on the basis of studies of very narrow clinical populations but are subsequently used much more broadly in clinical practice,» Naci and Ioannidis point out.

Diamond is also quick to point out that while the current study shows that COXEN could have been used to predict the most useful drug in many of these cases of advanced ovarian cancer, the actual use of the model will be possible only after validation with a prospective clinical trial.

Purushotham points out, «The feasibility of intraoperative CLI as shown in this study, in combination with the wide applicability of F -18-FDG across a range of solid cancers, provides a stepping stone for clinical evaluation of this technology in other solid cancer types that also experience incomplete tumor resection due to close or involved margins.»

The study was undertaken at Stockport NHS Foundation Trust, where doctors in the emergency department recorded their overall clinical judgement for ACS using a five - point Likert scale (from «definitely ACS» to «definitely not» ACS).

Researchers conducted a population - based perspective birth cohort study of 7,046 pregnant women, and categorized subjects into three groups: negative anti-tTG (control), intermediate anti-tTG (just below the clinical cut - off point used to diagnose patients with celiac disease) and positive anti-tTG (highly probable celiac disease patients).

Several limitations of the study are noted in the article, including that it was not powered to detect differences in clinical events or safety end points.

This goal of this study, led by Geisbert and Ian MacLachlan, executive vice president and chief technical officer of Tekmira Pharmaceuticals, was to determine whether it is possible to protect animals against a lethal MARV - Angola infection when treatment was started at a point when animals have detectable levels of the virus in their system and show the first clinical signs of disease.

Women in the early phases of menopause are more likely to have trouble sleeping during certain points in the menstrual cycle, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»

In an accompanying editorial, Dr. Timothy E. Morey of University of Florida points out the need for further studies to test the advantages of the new proliposomal formulation, especially in clinical situations where its properties may be most useful.

There are alternatives to centrifugation such as microfluidic technology, which has been widely studied for various applications in biological and chemical analysis, point - of - care testing and diagnostics, and clinical analysis.

Porter points out that tPA was not included in the clinical trial because a good result was seen with ultrasound / microbubbles alone in the pig study.

«This study points to the caudate nucleus as a likely target for clinical interventions to alleviate fatigue,» explained Dr. Wylie, who is associate director of Neuroscience Research and the Rocco Ortenzio Neuroimaging Center at Kessler Foundation.

«The clinical implications from an obstetric point of view are potentially huge,» says lead study author Arthur «Jason» Vaught, M.D., a maternal fetal medicine fellow at Johns Hopkins.

Dr. Fish also pointed out that the onsite team for this pilot study was composed of 11 Guinean healthcare workers who received, for the first time, relevant training in all aspects of conducting a clinical trial according to international standards.

«Our survey data point to a basic dilemma facing patients and physicians in our plural democracy,» said study author Farr Curlin, MD, assistant professor of medicine and a member of the MacLean Center for Clinical Medical Ethics at the University of Chicago.

Physicians and scientists at the University of Chicago Comprehensive Cancer Center are studying cancer at every point along the research spectrum, including gastrointestinal cancer clinical trials.

The third and most important point is related to the clinical evaluation of numerous WES variants of unknown significance, a very common occurrence in these types of studies.

A previous clinical study, led by Dr. Cook and published in 1992, also points to this protein.

Based on these accomplishments, Weiner contributed to the FDA's «Points to Consider» guidance document on moving gene based approaches safely to clinical study.

One study from Zeng et al. [130] compared acupuncture at KI3 and KI7 at two different time points — «open point time» and «closed point time» (the open or closed time point is determined by the Chinese medicine theory «Zi - Wu - Liu - Zhu» — the body's Qi and blood circulation schedule; acupuncture at the open point time results in maximum clinical effect and vice versa)[1].

The branch serves as a focal point at the NIH campus for the analysis of a wide variety of large - scale genomic data generated in the course of laboratory and clinical studies, with branch members actively involved in efforts aimed at developing new bioinformatic approaches for the analysis and visualization of these data.

A British analysis of 22 studies, published in February 2012 in the European Journal of Clinical Nutrition, found that taking at least 370 mg of magnesium per day reduced systolic blood pressure by 3 - 4 points and diastolic pressure by 2 - 3 points in 1,173 study subjects.

A lot of interesting stuff is lurking beneath the sea, according to Dr. Zeichner, who points to a study in the Journal of Clinical and Aesthetic Dermatology showing that a supplement containing marine protein powder, along with other nutrients and vitamins, helped regenerate skin cells in the scalp, resulting in increased hair growth after 90 days.

Many clinical studies have been conducted on these illnesses, where the results always point back to the same conclusion, in most instances.

He points to results discovered in lab and animal studies rarely holding up in human clinical trials.

Thankfully I can now point to a clinical study in which a high fat diet, in very short time, increased gastrointestinal transit time, reducing the likelihood of constipation occurring;

The article noted the many clinical studies showing the benefits of St. John's Wort for the treatment of depression, bit pointed out that the herb also has anti-inflammatory properties.

Dr Dariush Mozaffarian (Harvard Medical School, Boston, MA), who was also not involved with the study, said that heart - disease death, rather than nonfatal heart disease or total cardiovascular disease, is the clinical end point most likely influenced by fish oil.

At this point in time, there are not published clinical studies testing hunger and food consumption in elderly adults.

I realize that at this point this is now an older video, but even by 2010 Dr. Esselstyn had published his first clinical study.

In this study, the primary cognitive end - points measured were the mean change from baseline in the AD Assessment Scale - Cognitive subscale, and global scores in the AD Cooperative Study — Clinical Global Impression of Change (Henderson et al., 2study, the primary cognitive end - points measured were the mean change from baseline in the AD Assessment Scale - Cognitive subscale, and global scores in the AD Cooperative Study — Clinical Global Impression of Change (Henderson et al., 2Study — Clinical Global Impression of Change (Henderson et al., 2009).

Dr. Liu's findings may help explain why studies have shown that populations eating diets high in fiber - rich whole grains consistently have lower risk for colon cancer, yet short - term clinical trials that have focused on fiber alone in lowering colon cancer risk, often to the point of giving subjects isolated fiber supplements, yield inconsistent results.

An almost clinical psychological study, it questions the power dynamics between the long - suffering wife, threatened at one point with having her vagina sewn shut (the first Mexican audience laughed at the huge cord proposed for the deed) and the husband, unhinged by sexual desire — whether for his wife or his butler remains somewhat ambiguous.

However, it is important to point out that this study was done in a lab setting, not as a clinical trial.

Dr. Thomas Saunders, a clinical investigator from Dana Point, California, participated in one of the studies, and now plans tooffer ProHeart ® 6 to his clientele.

Professor JPA Ioannidis has made a career out of pointing out where epidemiology studies show poor replication, and the consequent implications for clinical practice.