Sentences with phrase «clinical studies testing»

At this point in time, there are not published clinical studies testing hunger and food consumption in elderly adults.

About a decade ago, Emory researchers stumbled upon fluciclovine's utility with prostate cancer, while investigating its activity in a patient who appeared to have renal cancer, according to radiologist David Schuster, who has led several clinical studies testing fluciclovine.

Not exact matches

Strikingly for Agios and partner Celgene, the therapy was in human clinical testing not so long ago (there was just a three year gap between the first human studies and Agios» regulatory submission to the FDA).

These studies make up more than 10 % of GSK's worldwide clinical - testing operations.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

Working with a third - party clinical testing group, Neba studied 275 children and adolescents ranging in age from 6 to 17 years old, all of whom exhibited signs of attention or behavioral concerns.

Straticyte is the first and only molecular diagnostic test for oral precancerous lesions that provides an objective and accurate prediction score as evidenced by retrospective clinical studies.

Among 11 study participants for whom data from the oral food challenge were either inconclusive or not available, a diagnostic algorithm based on clinical history, the results of a skin - prick test, and the values for peanut - specific IgE were used to determine whether or not a participant should be considered to have peanut allergy (Fig.

Quinoa cultivars were tested according to a study [9] reported in the American Journal of Clinical Nutrition with 4 of 15 cultivars having celiac - toxic epitopes barely below the 20 - mg / kg level that caused cytokine immune responses.

In a study published today (advance online publication) by the European Journal of Clinical Nutrition, approximately 95 percent of the 158 labeled gluten - free free food products tested by Gluten Free Watchdog tested less than 20 ppm gluten with approximately 87 percent testing below 5 ppm gluten.

* While there are, as of yet, no clinical studies to confirm the results, a laboratory study conducted at the College of Pharmacy at Oregon State University (OSU) presented at a December 2007 meeting of the American Society of Health - System Pharmacists found that an ointment containing benzethonium chloride with tea tree and white thyme oil worked best against all four tested MRSA strains, while ointments containing neomycin, polymyxin, and gramicidin also had some antibacterial effectiveness.

• Internet resource assignment • Review of 4 research studies • Counseling problems • Nutrition assignment • Clinical Assignment • Periodic testing • Community based breastfeeding class observation • Breastfeeding Class Curriculum includes topical outline; minimum 12 lesson plans, and 2 content teaching outlines.

Recent clinical studies prove that the MAM Perfect Pacifier supports healthy teeth and jaw development, and in a recent study, the MAM Perfect Pacifier was shown to be the tooth friendliest of any pacifiers tested.

As Larry Leverenz, Ph.D, ATC, a co-author of the groundbreaking 2010 study (4) that was the first to identify such athletes noted, because such athletes have not suffered damage to areas of the brain associated with language and auditory processing, they are unlikely to exhibit clinical signs of head injury (such as headache or dizziness), or show impairment on sideline assessment for concussion, all of which test for verbal, not visual memory.

Using DTI, researchers at Wake Forest found in a 2014 study [26] that a single season of high school football can produce changes in the white matter of the brain of the type previously associated with mTBI in the absence of a clinical diagnosis of concussion, and that these impact - related changes in the brain are strongly associated with a postseason change in the verbal memory composite score from baseline on the ImPACT neurocognitive test.

In addition, many studies have focused on sensitization to a particular antigen (ie, positive serum IgE or skin testing) rather than clinical disease.

Researchers at the NYU Langone Concussion Center reviewed studies that involved athletes who sustained a concussion during sporting activities and found the vision test, known as the King - Devick test, was 86 percent sensitive in detecting whether a concussion had occurred, as confirmed by clinical diagnosis.

Since the neuronal death can be recapitulated in directly reprogrammed patient neurons, Yoo said the new technique offers a way to study the details of how potential therapies — including drugs that are currently being tested in clinical trials — could rescue medium spiny neurons from death.

Studies have suggested antioxidant supplements has benefits for health, but several large clinical trials did not demonstrate a definite benefit for the formulations tested, and excess supplementation may even be harmful.

In medicine today, physician - scientists and basic scientists supplement support for their research by applying their expertise part time to develop and test commercial products.1 In my own field, vision science, university - based researchers obtain additional funding through clinical and electrophysiologic studies, pathology, imaging, biochemistry, and animal model development performed for pharmaceutical and instrument companies.

Mitchell guesses that there will probably be 10 more years of rigorous testing in animals before moving on to human clinical studies.

But a blood test could help researchers more easily identify people who might be good candidates for clinical trials of early interventions, says Steven Kiddle, a biostatistician at the University of Cambridge, who wasn't part of either study.

However, those guidelines from 2011 predate more recent clinical studies of HPV testing that were analyzed in today's paper.

This clinical study, published in the Proceedings of the National Academy of Sciences, tested the possibility of imaging inflammation in the pancreas of human volunteers using ferumoxytol, a coated iron nanoparticle approved by the FDA as an iron replacement therapy, and MRI.

Based on results of the current study described in a report online June 18 in the journal Cancer Cell, Johns Hopkins researchers say they are planning a phase I clinical trial to test the paclitaxel - fostamatinib combination therapy in patients with recurrent advanced ovarian cancer.

[1] At the end of the study after 12 months of supplementation, participants undertook clinical tests to assess their nervous system function including measures of muscle strength, coordination, mobility, tests of cognitive function including memory, and of psychological health.

«We are extremely encouraged by the results of this study and hope that this technology will be adapted for patients for testing in clinical trials in the not - too - distant future.»

But given its low cost, availability and safety history further study in a clinical trial to test its effectiveness against Zika virus in humans is merited.»

Yanagisawa and colleagues are now extending and expanding their study in hopes of bringing an amyloid blood test closer to routine clinical use.

«We have now found a potential mechanism, and at this point in our research, we need to test human participants in a blinded, placebo controlled clinical study — the same technique we used to study the behavioral effects of acupuncture in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.

«This study demonstrates that the road to a mitochondrial disease diagnosis is typically long and hard, involving visits to numerous clinical specialists, conflicting diagnoses, and repeated and sometimes painful and invasive testing,» says Michio Hirano, MD, the paper's senior clinical author and chief of the Neuromuscular Division at Columbia University Irving Medical Center.

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

Adding the two imaging tests resulted in the identification of subclinical atherosclerosis in 60 percent of the seemingly healthy study participants presenting with no clinical manifestations.

The team also conducted two clinical translation studies to test whether pharmacologically blocking miR -17-92 might have clinical relevance in the lupus - like condition and the scleroderma cGVHD model.

For the study, Bég recruited 100 of her patients who volunteered clinical samples for testing.

The study caught the attention of vaccine maker Sanofi Pasteur, which plans to test the vaccine in clinical trials.

Following the success of this preliminary safety and feasibility study, more patients are being recruited for a larger clinical trial of the procedure to test the efficacy and durability of the procedure.

Last month, Biopure launched a revamped clinical development program, emphasizing testing in Europe, with three phase II clinical trials planned for 2008 to study the impact of its product on heart attack patients, chemotherapy patients with anemia and the terminally ill.

The researchers will soon launch a three - month clinical study to test sperm counts in men taking the drug.

The study would mark the first clinical test of the cells.

«This vaccine appears to be safe for patients, and elicits a broad anti-tumor immunity — we think it warrants further testing in larger clinical trials,» said study lead author Janos L. Tanyi, MD, an assistant professor of obstetrics and gynecology at Penn Medicine.

Importantly, these cells are readily detectable in patients» bloodstream, allowing for any clinical tests to be minimally invasive and pain - free for patients,» said Professor Salvatore Albani, Director, SingHealth Translational Immunology and Inflammation Centre (STIIC), Professor, Duke - NUS Medical School and Senior Clinician Scientist, KK Women's and Children's Hospital (KKH), who is the principal investigator of the study.

«It was clear from our findings that many people with IBS should have their vitamin D levels tested, and the data suggests that they may benefit from supplementation with vitamin D. «As a result of this exploratory study, we're now able to design and justify a larger and more definitive clinical trial.»

The study makes progress toward using gene editing to prevent genetic diseases, but there's still has a long way to go before clinical testing can begin, says Janet Rossant, a developmental biologist at the Hospital for Sick Children and the University of Toronto.

But vaccines that only contained HIV's surface protein looked lackluster in animal and test tube studies, and then proved worthless in large - scale clinical trials.

«While randomized clinical trials are needed to test whether this is a causal relationship, these findings indicate doctors should consider using or re-starting ACEIs and ARBs as first - line blood pressure medications for patients undergoing peritoneal dialysis,» said Jenny I. Shen, MD, an LA BioMed researcher and corresponding author of the study.

p > In a study of 61 people treated for the bacteria that causes Lyme disease, Johns Hopkins researchers conclude that fatigue, pain, insomnia and depression do indeed persist over long periods of time for some people, despite largely normal physical exams and clinical laboratory testing.

«In the clinic, we frequently test myc levels in patients» tumors, for disease prognosis and to predict treatment response,» said Michael Pourdehnad, MD, a clinical oncologist at UCSF with Ruggero's lab and the first author of the study.

«After years of collaboration with some of the world's leading prostate cancer researchers and medical institutions who have studied the scientific and clinical benefits of phi, we are pleased that the test is now available to help physicians and patients with an elevated PSA test result, more accurately detect prostate cancer2,» said John Blackwood, senior vice president, Chemistry / Immunoassay Business Unit, Beckman Coulter Diagnostics.

With a view to clinical studies (tests on humans) it is important to note that the effects on the tumor vasculature were even observed at chloroquine concentrations that had little effect on autophagy in the cancer cells.