Sentences with phrase «clinical study involved»

She worked as an infant caregiver for 12 years and interned as a Child Life Specialist, family / social therapist, and assisted in clinical studies involving children's personality and social psychology.

A clinical study involving thousands of patients is in the planning phases.

In a randomized clinical study involving adults age 56 to 71 that recently published in Neurobiology of Aging, researchers found that after cognitive training, participants» brains were more energy efficient, meaning their brain did not have to work as hard to perform a task.

«The antibody affinity should now also be taken into consideration in clinical studies involving LADA patients.»

At least 15 clinical studies involving approximately 900 patients document mild adverse reactions.

But one clinical study involving 24 healthy female subjects showed «synergistic» effects on cognition and mood, which incidentally translated into improved blood pressure.

In a multicenter, randomized clinical study involving men and women with mild to moderate eczema, subjects using this Aveeno cream (versus an un-fragranced placebo lotion that did not contain oats) experienced improvements in skin pH and barrier function (that is, the skin's ability to hold water and block irritants), as well as a dramatic hike in hydration (266 percent!)

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Mar. 18, 2013 — People suffering from complicated grief may have difficulty recalling specific events from their past or imagining specific events in the future, but not when those events involve the partner they lost, according to a new study published in Clinical Psychological Science, a journal of the Association for Psychological Science.

The alleged lack of scientific studies and the amount of clinical judgment involved in concussion management, and the lack of uananimity, either about grading the severity of concussions or in return to play guidelines, while it complicates our efforts to educate parents on concussions, should not be used as an excuse to do nothing.

Finally, neurodevelopmental research has suggested that the factors in breast milk that may be responsible for the improved cognitive abilities of breastfed children may involve long chain polyunsaturated fatty acids and, particularly, docosahexaenoic acid (DHA), 10 with some clinical studies in which infant formula was supplemented with DHA suggesting possible improvements in visual acuity and cognitive ability in preterm infants given the DHA - supplemented formula.13

Researchers at the NYU Langone Concussion Center reviewed studies that involved athletes who sustained a concussion during sporting activities and found the vision test, known as the King - Devick test, was 86 percent sensitive in detecting whether a concussion had occurred, as confirmed by clinical diagnosis.

«I've been involved in clinical trials for 30 years,» says the study's lead author Bonnie Ramsey, a professor of pediatrics at the University of Washington School of Medicine in Seattle.

«This study demonstrates that the road to a mitochondrial disease diagnosis is typically long and hard, involving visits to numerous clinical specialists, conflicting diagnoses, and repeated and sometimes painful and invasive testing,» says Michio Hirano, MD, the paper's senior clinical author and chief of the Neuromuscular Division at Columbia University Irving Medical Center.

Weight loss surgery can curb alterations in brain activity associated with obesity and improve cognitive function involved in planning, strategizing and organizing, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

The neuroprotective effects of nicotine were studied in a randomized clinical trial involving 67 subjects in the early stages of Alzheimer's disease, where memory was slightly impaired but decision - making and other cognitive abilities remained intact.

This study involved a subset of patients enrolled in a clinical trial of pediatric AML called AML02.

«I think this is a step towards making sense out of a lot of data — genetic data, environmental data, epidemiological data — to help us understand factors that contribute to long and healthy life,» says Winifred Rossi, deputy director of the Division of Geriatrics and Clinical Gerontology at the National Institute on Aging, who wasn't involved in the study.

The study involved 2,822 community - dwelling older men at six clinical centers in the U.S. Participants had a mean age of 76 years.

Instead of a taking a clinical approach to reducing opioid abuse, which often involves prescribing alternative medications such as naloxone, the study seeks to change behavior.

The study involved 3,896 participants who were free of clinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis and who underwent cardiac magnetic resonance imaging (study involved 3,896 participants who were free of clinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis and who underwent cardiac magnetic resonance imaging (Study of Atherosclerosis and who underwent cardiac magnetic resonance imaging (MRI).

The new six - year study, «Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18 - month randomized clinical trial,» involved 54 adults and was led by Shaun Eack, Ph.D., M.S.W., Pitt's David E. Epperson Professor of Social Work and Psychiatry, and Nancy Minshew, M.D., Pitt professor of psychiatry and neurology.

Purushotham points out, «The feasibility of intraoperative CLI as shown in this study, in combination with the wide applicability of F -18-FDG across a range of solid cancers, provides a stepping stone for clinical evaluation of this technology in other solid cancer types that also experience incomplete tumor resection due to close or involved margins.»

The study included 124 newly diagnosed patients at 25 clinical trial sites in the U.S. Two - thirds of the patients were treated with ICT - 107, an experimental vaccine based on immune system cells called dendritic cells that were exposed to six synthetic proteins, or antigens, known to be involved in GBM development.

However, RA professionals are increasingly involved with products during the research and development phases, in the design and monitoring of clinical studies, marketing, advertising, and communications.

The study, published in the June issue of the Journal of Clinical Sleep Medicine, reaffirms numerous small - scale studies in the United States, Western Europe and Japan, but it does so using data compiled across six middle - income nations and involving more than 30,000 subjects for a long - term project that began in 2007.

It's essential that people feel they are in a safe, comfortable setting with someone who can oversee the experience, says Alicia Danforth, a clinical psychologist at the Harbor — UCLA Medical Center in Torrance, California, who is involved in MAPS - sponsored trials studying MDMA's effects on social anxiety in adults with autism.

The MSU - led team's study, «Explaining Alcohol Use and Suicide Risk: A Moderated Mediation Model Involving Insomnia Symptoms and Gender,» was published in the December 2014 edition of Journal of Clinical Sleep Medicine.

In her current role as vice president of clinical development, Hooker's job involves studying «the genetic testing market and how it changes, and thinking about ways that we can learn from that information to better integrate genetic testing into the health care system,» she says.

Other researchers involved in the study are Jennifer Maloney, M.D., Amarjot Kaur, Ph.D., Nancy Lui, Ph.D., and Hendrik Nolte, M.D., Ph.D., at Merck; David Bernstein, M.D., at the Bernstein Clinical Research Center and University of Cincinnati College of Medicine, in Ohio; Thomas Casale, M.D., at Creighton University in Omaha, Neb.; Robert Fisher, M.D., at Allergy Research and Care in Milwaukee, Wis.; Kevin Murphy at Boys Town National Research Hospital in Omaha, Neb.; and Kristof Nekam, M.D., at Hospital of the Hospitaller, Brothers of St. John of God, in Budapest, Hungary.

The study, which is published today in the Journal of Clinical Hypertension and is supported by Barts Charity, devised a novel treatment strategy for 55 patients, involving fractional dosing with tablets (halving or quartering pills), liquid formulations of antihypertensive drugs and patch formulations of antihypertensive drugs — plus use of unlicensed drugs that lower blood pressure.

Holton and Nigg employed a rigorous study design that involved parental reports, diagnostic interviews, and consensus of two clinical experts to screen for ADHD and additional psychiatric disorders.

The study involved 12 clinical centers, and enrolled infants with a cataract in one eye.

These findings also suggest a mechanistic basis for potential treatments involving the painless electrical stimulation of the amygdala, which are currently being studied in ongoing clinical trials.

The company paid scientists at Duke University School of Medicine and Florida Clinical Research Center to run a four - week study involving 80 children ages eight to 12 — 40 with ADHD who were not taking medications and 40 neurotypical, or those whose functions were within a normal range.

Our results suggest the need for future studies involving long - term ambulatory cardiac monitoring to better delineate the risk associated with transient vs persistent perioperative AF, as well as randomized clinical trials to determine optimal strategies for antithrombotic therapy in patients with perioperative AF and a significant burden of other risk factors for stroke,» the authors write.

NIH also has similar expectations for studies that involve the use of de-identified cell lines or clinical specimens.

The white paper recommends that practitioners follow relevant guidance documents and that deviation from consensus recommendations should be supported by clinical studies or pursued in the setting of a clinical trial approved by an institutional review board; that practitioners receive training in a new procedure before beginning its practice, that the training should include a practical, «hands - on» component and that all team members directly involved with the radiation therapy decisions should participate in at least five proctored cases before performing similar procedures independently; and that professional societies should accelerate the generation of new or updated guidance documents for the following disease sites and techniques: skin, central nervous system, gastrointestinal, lung or endobronchial and esophagus, and, while outside the charge of this panel, assess the need for updated guidance documents for accelerated partial breast irradiation using electronic brachytherapy.

Although further studies are necessary, potential clinical applications of the team's finding would involve developing methods or drugs that prevent Mtb from entering M - cells.

This study provides evidence for what experts have previously hypothesized about coaching, says Jonathan Fader, a clinical and sport psychologist in New York City who was not involved in the study.

«I don't know of any studies that look at both active and former athletes with the type of breadth of assessment that is going on in the fighters study,» said Robert Stern, a clinical neuroscientist who oversees clinical research at Boston University's CTE Center and who is not involved in the fighters study.

Wong was not involved in the study, but he is part of a team of researchers currently testing the device in a phase III clinical trial, which includes more than 200 glioblastoma patients in the United States and Europe.

Trial studies suggested that fish oil could help, but larger clinical trials proved inconclusive — possibly because the trials involved people with advanced cancers that were difficult to treat.

«Involving the GP practices in the Salford Lung Study allowed the team to create an unsupervised environment for the patients, enabling important factors in usual clinical care — such as adherence, frequency of dosing and persistence of good inhaler technique — to rightly influence the trial outcomes.

The research did uncover some positive findings, said VJ Periyakoil, MD, clinical associate professor of medicine at Stanford and director of the Stanford Palliative Care Education and Training Program, who was not involved with the study.

The current study combines data from five clinical trials involving a total of 1,287 people, including the SWIFT PRIME trial led by Saver, that show these devices improved outcomes for people with acute ischemic strokes due to large vessel blockage.

The GP practices were involved in ensuring the study not only had access to specific COPD patients but also that the usual clinical care provided by the practices was built into the trials — the study was therefore rooted in a real clinical environment unlike tradition efficacy trial model.

The study involved seven clinical centres with pain management expertise across Canada located in Fredericton, Halifax, London, Montreal, Toronto and Vancouver.

Professor Peter Naredi, the ECCO scientific co-chair of the Congress, who was not involved in the research, commented: «Although the CheckMate 067 study has already reported that a combination of two checkpoint inhibitors, nivolumab and ipilimumab, is superior to either drug alone, the results presented here in Vienna have important clinical implications.

This study has been published in the Neuroimage journal and is part of the ActiveBrains project, which is a randomized clinical trial involving more than 100 overweight / obese children led by Francisco B. Ortega.