Sentences with phrase «clinical translation»
The phrase "clinical translation" refers to the process of applying scientific discoveries made in research laboratories to develop new medical treatments or interventions that can be used to help patients in real-world healthcare settings. Full definition
The program integrates the highest quality of basic science laboratory studies with a fundamental understanding of the unique requirements of clinical translation of the discoveries.
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Previous studies have demonstrated the bone - forming potential from other cell sources, yet serious caveats for clinical translation remain.
It's not yet ready for clinical translation, he says, «but it's an important step forward».
Since 2006, the award - winning peer - reviewed journal Regenerative Medicine (IF: 2.868, MEDLINE - indexed) has been at the forefront of publishing the best in clinical translation, commercialization and regulation.
The team also conducted two clinical translation studies to test whether pharmacologically blocking miR -17-92 might have clinical relevance in the lupus - like condition and the scleroderma cGVHD model.
«Over the past ten years, the central goal of my research has been focused on finding and introducing overlooked factors at the nanobio interfaces to minimize this bench - to - clinic gap, which might pave a way to accelerate successful clinical translation of nanoparticles.
Dr. Robins will also co-lead the ISSCR Workshop on Clinical Translation: Date / Time: June 23, 2015 at 09:00 — 18:00 Location: Karolinska Institutet, Huddinge Campus, Stockholm, Sweden
«Inspired by the collaborative research at BioFulcrum, we wanted to establish Tenaya to integrate new findings and tools in the cardiac field and advance them towards clinical translation,» said Kang.
DERISK: Proving and maturing the science and technology to guide clinical translation.
December 21, 2016 By Ann Perry A technology that could increase the number of lungs available for transplantation and a stem - cell based treatment that has the potential to reverse heart failure are both a step closer to reality after winning Medicine by Design Clinical Translation and Commercialization Awards.
«And since many of the cancer - killing interactions we discovered involve already FDA - approved drugs, it may mean they could reach clinical translation rapidly.
«It facilitates a key step toward clinical translation of NIR techniques for breast tumor margin assessment, both here at Dartmouth, and in the biomedical community at large.»
They write, «There are exciting and immediate implications for early clinical translation; the discovery of easily accessible biomarkers in peripheral blood to predict disease susceptibility, progression or response to therapy and the potential for new therapeutic targets.»
The Insigneo Institute hosts an annual showcase bringing together some of the world's leading in silico experts, with clinical translation as the theme of this year's event.
Microphysiological systems (MPS) technology offers an opportunity to support enhanced preclinical to clinical translation through the generation of higher - quality preclinical physiological data.
• over 100 specialists • matrixed, interdisciplinary teams • rapid clinical translation • worldwide research collaborations • state - of - the - art equipment • specialized graduate and doctoral training
Concrete examples from clinical testing and research results will be used to address the social and ethical dimensions of using such targeted information in clinical translation.
«We're excited about this technique, and are seeking funding to pursue further studies and potential clinical translation,» Gu adds.
5:00 - 6:00 pm — Shinya Yamanaka and Deepak Srivastava join a panel on ethical considerations for clinical translation of iPS cell research.
«Drugs that specifically target PGE2 pathways have already been developed and tested in animals, so our results have excellent potential for clinical translation, not only for the treatment of influenza, but other viral respiratory infections that interact with similar host immune pathways,» says senior study author Divangahi, who is also a member of the Infectious and Immunity Axis at the Research Institute of the McGill University Health Centre (RI - MUHC).
The reason behind this wide gap between the efforts and successful clinical translation is, at least in part, because of the existence of several overlooked factors at the nanobio interface.»
«When most people think about cancer genetics, they think about single key mutations that foster tumor formation — very specific things like the BRCA genes,» said Joe R. Delaney, PhD, a fellow in the Clinical Translation program at UC San Diego Moores Cancer Center and lead author of the paper published February 15 in Nature Communications.
The clinical translation studies also found that miR - 17 blockade alleviated proteinuria (in the lupus - like condition) and scleroderma symptoms.
Despite their extensive therapeutic exploration, growth factors have been very limited in terms of clinical translation, mostly because drug formulations often fail to properly reflect the biological function of growth factors in wound healing.
«By re-engineering the molecules, we are able to exploit that interaction and open the way for clinical translation, turning these molecules into useful drugs.»
Authors of the article «Clinical translation of a dual integrin?
Our current results present a milestone with regard to clinical translation, because we could demonstrate how preclinical knowledge can be applied to human beings.»
His laboratory has made several seminal contributions to the field of chimeric antigen receptors (CARs), from their conceptualization and optimization to their clinical translation for cancer immunotherapy.
The Insigneo Institute is at the forefront of clinical translation — ensuring that the developments in the laboratory benefit patients as quickly as possible.
Clinical translation is the obvious answer, and hopefully this research will represent an important step in reducing the risk of stem cell treatment for diabetes, as well as other diseases.
For sustained contributions to the field of biophotonics, spanning over thirty years and encompassing outstanding research, technology development, clinical translation and training and education, in the areas of light dosimetry, photodynamic therapy fluorescence and Raman endoscopy, microscopy and nanophotonics
These encouraging data suggest that transient BIO treatment may represent a safe and rapid strategy to enhance the osteogenic potential of patient BM stem cells, a bone defect repair approach that the authors believe is a faster path to clinical translation than the treatment of purified and ex vivo - amplified hMSCs.
What are the challenges of single vs multi-gene based diagnostics in terms of regulatory approval and clinical translation?
Eliminating bias and accelerating the clinical translation of oral microbiome research in oral oncology — Rohit Kunnath Menon — Oral Oncology
The division provides a unique interface between basic and applied research through to clinical translation.
QUT Vice-Chancellor Professor Margaret Sheil said the Centre was at the cutting edge of how science and clinical translation is done.
The universities provide teams with funding and the tools needed for clinical translation, particularly things basic scientists might not be familiar with.
«This paper takes us a number of steps forward to the clinical translation of IVF techniques to prevent or reduce the risk of transmission of mitochondrial mutations.
We look forward to continued advances in 2017 that support the rigorous, ethical standards set forth in the 2016 Guidelines for Stem Cell Research and Clinical Translation, and help address issues of human health around the world.
An endowed professorship is considered the highest honor in academic medicine and recognizes extraordinary talent in research, clinical care and teaching, and it provides solid and sustaining funding to an accomplished faculty member to support his or her continued focus on radiation oncology research and its clinical translation.
Though the work was done in mice, it has the potential for clinical translation, according to Shapiro.
Useful guidelines for the clinical translation of stem cells and a patient handbook on stem cell therapies.
Learn more about the ISSCR's guidelines for stem cell research and clinical translation.
Towards the clinical translation of intra-articular injection of MSCs, the group of Kang Sup Yoon at the Seoul National University College of Medicine, Seoul, Korea report on their a proof - of concept phase I / II clinical trial intra-articular injection of autologous adipose tissue derived mesenchymal stem cells (AD MSCs)[6].