Seed Money for Translational Pilot Projects Charis Eng, MD, PhD, Chair, Genomic Medicine Institute, advises all faculty that the Cleveland Clinical and Translational Sciences Collaborative (CTSC) and the School of Medicine, Case Western Reserve University, will provide seed money to faculty in multidisciplinary programs for Pilot Projects that will lead to effi cient use of resources and support of inter-institutional,
clinical translational research in the City of Cleveland.
This clinical research center has been able to train all types of students on
clinical translational research in anxiety and at the same time has an extensive role in community education and outreach to improve access to quality mental health services.
Not exact matches
«The most common time there is conflict of interest is not with inventorship,» says Harry Greenberg, senior associate dean for
research at the Stanford University School of Medicine in Palo Alto, California, and director of the Stanford Center for Clinical and Translational Education and R
research at the Stanford University School of Medicine
in Palo Alto, California, and director of the Stanford Center for
Clinical and
Translational Education and
ResearchResearch.
«
In Portugal, we don't have a lot of... companies that do
translational research, so the goal was really to apply our knowledge to the
clinical field and to be able to establish a bridge,» Outeiro says.
That priority influences the design of
research questions, Weng notes, and encourages scientists involved
in basic
research, including postdocs, to participate
in «very dynamic» collaborations with
translational and
clinical groups.
With support from Ohio State's Center for
Clinical and
Translational Science (CCTS), Dr. Bonny's
research team was able to comb through past
research to identify the top 30 nutrients that were most likely to influence the growth of fat tissue
in a low - estrogen environment.
D. degrees train individuals
in clinical and basic
research, but
translational research programs strive to integrate these two sides of medical science by connecting people and building networks.
In either case, the goal is becoming competent to interpret, evaluate, and discuss different types of
research, rather than conducting it all yourself, says Doris Rubio, professor of medicine, biostatistics, nursing, and
clinical and
translational science at the University of Pittsburgh.
The world of
clinical and
translational research requires the support of individuals with varying expertise
in diverse scientific and professional languages.
In the United States, most training opportunities are through the Clinical and Translational Science Awards (CTSAs), which were launched in 2006 based on the 2003 National Institutes of Health (NIH) Roadmap for Medical Researc
In the United States, most training opportunities are through the
Clinical and
Translational Science Awards (CTSAs), which were launched
in 2006 based on the 2003 National Institutes of Health (NIH) Roadmap for Medical Researc
in 2006 based on the 2003 National Institutes of Health (NIH) Roadmap for Medical
Research.
Translational — bench to bedside —
research remains a particular challenge
in the
clinical neurosciences,
in large part due to the inaccessibility of the brain.
The pioneering
research led by academics from the Sheffield Institute of
Translational Neuroscience (SITraN),
in collaboration with scientists from the University of York, supports the fast - tracking of the drug ursodeoxycholic acid (UDCA) for a
clinical trial
in Parkinson's patients.
A
clinical trial conducted by researchers at the Virginia G. Piper Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM - 398, given in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously - treated pancreatic
clinical trial conducted by researchers at the Virginia G. Piper Cancer Center
Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM - 398, given in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously - treated pancreatic
Clinical Trials, a partnership between Scottsdale Healthcare and the
Translational Genomics
Research Institute (TGen), showed that a new drug called MM - 398, given
in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate
in patients with advanced, previously - treated pancreatic cancer.
The other major opportunity for
translational research in clinical neuroscience is brain imaging.
NIH launched the CTSA program
in 2006 to fund
clinical and
translational research hubs at institutions around the country, which are individually known as CTSAs.
The National Institutes of Health's (NIH's) Roadmap for Medical
Research acknowledges the importance of behavioral and social science research, and the agency's Clinical and Translational Science Awards require a behavioral science component in the programs of awardee insti
Research acknowledges the importance of behavioral and social science
research, and the agency's Clinical and Translational Science Awards require a behavioral science component in the programs of awardee insti
research, and the agency's
Clinical and
Translational Science Awards require a behavioral science component
in the programs of awardee institutions.
«Bioinformatics Instruction & Consultation, Collaboration, Evaluation» [PDF, 2.38 MB] Kristi L. Holmes, Ph.D., Becker Medical Library, Washington University
in St. Louis «Community Engagement: Lost
in Translation» [PDF, 2.1 MB] Layne Johnson, Ph.D.,
Clinical and
Translational Science Institute, University of Minnesota «Supporting
Clinical Research» [PDF, 785 KB] Jennifer A. Lyon, M.S., MLIS, Biomedical and Health Information Services, University of Florida «Library - based Support for
Translational Medicine» [PDF, 403 KB] Michele R. Tennant, Ph.D., MLIS, Biomedical and Health Information Services, University of Florida
The contest involves writing a 500 - word essay
in English, or 1,500 characters
in Japanese, about
translational medicine, which is a relatively new scientific field where human health is promoted by facilitating communication among those dedicated to basic and
clinical research and its application.
Back
in the US, and further along the
translational pipeline is Doug Lowy, of the NIH
in Bethesda, Maryland, who has already experienced the potential of harnessing basic
research for
clinical use.
The
research, led by Knut Wittkowski, biostatistician
in the Center for
Clinical and
Translational Science at The Rockefeller University Hospital, is a twist on a traditional data - mining technique known as a genome - wide association study.
For Fuster, «This is a clear example of the type of the collaborative and
translational research favored by the CNIC,
in which
research groups with different interests and perspectives collaborate on
clinical problems that would not be easily resolved by teams working
in isolation.»
«Since several BACE1 inhibitors are currently being evaluated
in clinical phase 3 trials for the treatment of Alzheimer's disease, the identification of potential side effects will be of great importance to ensure a positive
clinical outcome,» said Dr. Jochen Herms, a Professor of
translational brain
research at Ludwig - Maximilians - University Munich.
«Activation of these cell receptors appear to prevent brain cells from cleaning out the trash — the toxic buildup of proteins, such as alpha - synuclein, tau and amyloid, common
in neurodegenerative diseases,» says the study's senior author, neurologist Charbel Moussa, MBBS, PhD, director of Georgetown's Laboratory for Dementia and Parkinsonism, and scientific and
clinical research director of the GUMC
Translational Neurotherapeutics Program.
At Brigham and Women's, she led
clinical trials
in lung transplants and found herself happily pursuing a career
in «
translational»
research that applied basic science to
clinical studies.
«The exciting
research results being presented today underscore how transplants are becoming an increasingly successful treatment option for more patients with blood cancer than ever before,» said Jeffrey Miller, MD, moderator of the press conference and Deputy Director of the Masonic Cancer Center and the
Clinical and
Translational Sciences Institute at the University of Minnesota
in Minneapolis.
His primary
clinical and
research focus is dementia, with specific areas of interest including biomarkers to assist
in the diagnosis and understanding of disease mechanisms for Alzheimer's and Parkinson's disease, and
translational research using novel therapeutic approaches.
Her
research is both
translational and
clinical in nature and centers on the human genetics of healthy skin aging and diseases related to aging skin, including new treatments for advanced basal cell skin cancers.
«We are delighted to receive this CIRM grant that will drive our
translational research from the laboratory to the clinic,» Slamon said, «and allow us to test our targeted drug
in a phase I
clinical trial.»
BWF
Clinical Scientist Awards
in Translational Research provide $ 750,000 over 5 years to faculty members
in the late - assistant - professor or early - associate - professor stages of their careers.
Still, embarking on a career
in translational research is hazardous, says Anthony Hayward, clinical research director for NIH's National Center for Research Re
research is hazardous, says Anthony Hayward,
clinical research director for NIH's National Center for Research Re
research director for NIH's National Center for
Research Re
Research Resources.
William Crowley, director of
clinical research for Massachusetts General Hospital
in Boston, observes that, although NIH's many programs to support training
in clinical and
translational research have been «spectacular,» the academy is now filled with well - trained
translational researchers, all trying to land independent
research grants just as the NIH pay line is plummeting.
Now,
translational research has emerged as a field in its own right, aided in large part by the National Institutes of Health (NIH) Roadmap for Medical Research, a collection of initiatives that prioritize efforts to shepherd biomedical discoveries into clinical appl
research has emerged as a field
in its own right, aided
in large part by the National Institutes of Health (NIH) Roadmap for Medical
Research, a collection of initiatives that prioritize efforts to shepherd biomedical discoveries into clinical appl
Research, a collection of initiatives that prioritize efforts to shepherd biomedical discoveries into
clinical application.
CTSciNet combines a comprehensive career - development resource with a soon - to - be-launched online community open to everyone interested
in careers
in clinical and
translational research.
All of the authors share a deep interest
in clinical and
translational research, and the editorial expresses a collective commitment to the development of an effective
clinical and
translational research work force.
These ideas are summarized
in a new paper, «Neuropsychiatric Signs and Symptoms of Alzheimer's Disease: New Treatment Paradigms,» published
in the journal Alzheimer's & Dementia:
Translational Research &
Clinical Interventions.
«Together with our partners, we are aiming at establishing a
research cluster
in the Rhine - Main area that focuses on
translational and
clinical research for the treatment of non-alcoholic fatty liver disease,» emphasized Schattenberg and Schuppan.
Not all CTSA programs bolster
translational research in the same way, points out NCRR Division Director of Clinical Research Anthony
research in the same way, points out NCRR Division Director of
Clinical Research Anthony
Research Anthony Hayward.
«They should follow their own basic interests, whether
in biochemistry, microbiology, or training as a physicist, but really think about getting extra training through a degree - granting program
in clinical and
translational research because this is going to position them to be more forward thinking,» says NCRR's Alving.
This advance
in breast cancer
research reflects the mission of Stem Cell Reports to provide an open - access forum that communicates basic discoveries
in stem cell
research as well as
translational and
clinical studies.
To get an extra edge, some scientists are looking to get degrees
in clinical and
translational research.
Dr. Azorsa is currently an associate professor
in TGen's
Clinical Translational Research Division and a research assistant professor in the Department of Basic Medical Science at the University of Arizona College of Medicine —
Research Division and a
research assistant professor in the Department of Basic Medical Science at the University of Arizona College of Medicine —
research assistant professor
in the Department of Basic Medical Science at the University of Arizona College of Medicine — Phoenix.
«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved
in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center
Clinical Trials Program at Scottsdale Healthcare and deputy director of the
Clinical Translational Research Division of the
Translational Genomics
Research Institute (TGen)
in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved
in tumor growth.»
JACC is the flagship for a family of journals — JACC: Cardiovascular Interventions, JACC: Cardiovascular Imaging, JACC: Heart Failure, JACC:
Clinical Electrophysiology and JACC: Basic to
Translational Science — that prides themselves
in publishing the top peer - reviewed
research on all aspects of cardiovascular disease.
«We are getting closer and closer to
translational elements of
research, which involves testing
in animal and
clinical facilities.
The BWF Board has decided to discontinue the
Clinical Scientist Awards
in Translational Research (targeted at mid-career, established investigators) and, instead, to focus its involvement in translational research on providing early - career support for physicia
Translational Research (targeted at mid-career, established investigators) and, instead, to focus its involvement in translational research on providing early - career support for physician sci
Research (targeted at mid-career, established investigators) and, instead, to focus its involvement
in translational research on providing early - career support for physicia
translational research on providing early - career support for physician sci
research on providing early - career support for physician scientists.
The designation recognizes the Center's collaborative environment and expertise
in harnessing
translational research to bridge scientific discovery to
clinical delivery, with the ultimate goal of successfully introducing novel diagnostic, therapeutic and preventive approaches to cancer.
On Friday 19 February, CTSciNet, an online community for people pursuing careers
in clinical and
translational research who seek to speed the translation of scientific breakthroughs into real - world therapies, will host panel discussion with top experts
in the field.
My colleagues and I are also engaged
in translational research, where we apply precision medicine techniques
in ongoing and completed
clinical trials.
About the Anna - Maria Kellen
Clinical Accelerator The Anna - Maria Kellen Clinical Accelerator, the clinical research program of the Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
Clinical Accelerator The Anna - Maria Kellen
Clinical Accelerator, the clinical research program of the Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
Clinical Accelerator, the
clinical research program of the Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
clinical research program of the Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
research program of the Cancer
Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic
research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
research and treatment centers worldwide, to provide scientists and clinicians with expertise
in cancer immunotherapy access to resources they need to advance ambitious
clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
clinical and
translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innovation.
Physiological Reports to provide peer reviewed
research on basic,
translational and
clinical physiology; international call for Editor -
in - Chief to be issued