Sentences with phrase «clinical trials of drugs»

The first clinical trials of drug treatments are already under way.

The committee suggest this is part of a bigger problem whereby clinical trials of all drugs with negative results are twice as likely to be withheld from the public as those with positive results.

A new study finds that rising placebo responses may play a part in the increasingly high failure rate for clinical trials of drugs designed to control chronic pain caused by nerve damage.

In general, the researchers found liraglutide 3 mg to have a safety profile that was similar to that found in previous clinical trials of the drug in individuals with Type 2 diabetes treated with lower doses.

That company, Compass Pathways, said on Wednesday that it plans to start clinical trials of its drug starting in the first three months of 2018.

This week, Gordon co-authors a publication that describes the first clinical trial of a drug for progeria.

The FDA had halted early clinical trials of the drug on 3 July, but said on 7 August that the drug could potentially be given to infected patients.

But it will undoubtedly be a long time before any potential therapies are tried in humans: an early - stage clinical trial of a drug to treat fragile X syndrome, for example, was published last year (S. Jacquemont et al..

To understand how this pathway is implemented, in a recent study published in JAMA, researchers at Brigham and Women's Hospital and the London School of Economics and Political Science (LSE) examined the pre-approval and post-approval clinical trials of drugs granted FDA Accelerated Approval between 2009 and 2013.

Researchers evaluate the features of pre-approval and post-approval clinical trials of drugs granted accelerated approval by the FDA.»

Physicians who want to prescribe Keytruda, on the other hand, must test for that protein since Merck's clinical trials of the drug focused on people with PD - L1 (and is more effective for those patients).

He said he plans to start clinical trials of a drug KaloBios has been evaluating for treatment of chronic myelomonocytic leukemia.

In 2002, Home Secretary David Blunkett announced that he might permit the medical use of cannabis if clinical trials of the drug were successful.

The first clinical trial of a drug intended to delay the onset of symptoms of Huntington disease (HD) reveals that high - dose treatment with the nutritional supplement creatine was safe and well tolerated by most study participants.

In a paper accepted for publication in the journal Pain, researchers at McGill University in Montreal analyzed the results of 84 clinical trials of drugs conducted around the world from 1990 to 2013.

«That would be a great result if it was seen in a normal clinical trial of a drug.»

But John Collinge of University College London, UK, and colleagues, who reported the clinical details of the most recent case, say people at high risk of vCJD should be informed, so they can be enrolled in clinical trials of drugs which are hoped to delay or prevent the onset of the disease.

Confidence in biotechnology companies was jolted last week by the news that a major clinical trial of a drug to combat severe blood poisoning had been halted.

Later, during the second clinical trial of the drug in 1943, one of 15 patients died from a strep infection because the microbe had become resistant to the antibiotic.

The researchers are now running a larger, double - blind, randomized clinical trial of the drug in 152 patients, planning to evaluate its effectiveness next October.

Two months later, the drug company Wyeth sent a letter to doctors warning of increased suicidal thoughts among youngsters in clinical trials of their drug Effexor.

Still, the study «certainly sets the stage for future clinical trials of drugs that show promise to (one day) improve the health of older adults.»

In early clinical trials of these drugs, we noticed that in some breast cancer patients the tumors didn't just remain the same size — as would be expected with drugs that interfere with cell division — but began to recede, sometimes quite dramatically, said Goel.»

The company is preparing to apply for permission to start clinical trials of the drug, but says that it must first build a high - grade dairy and purification unit to generate the required amounts to a high enough standard of purity.

«It's the first clinical trial of a drug with this action in patients with cancer,» says Peter Lewis, the director of research and development.

Vtesse is currently running a late - stage clinical trial of the drug, a large sugar molecule known as a cyclodextrin, in which it is injected by lumbar puncture into the spinal fluid of children with the disease (see «Why are people fighting over a promising treatment for a fatal childhood disease»).

Nir Barzilai is planning the first clinical trial of a drug that could slow the body's deterioration

A phase - 1 clinical trial of the drug in human patients with pulmonary hypertension is expected to begin this winter.

Separately, it alleges, citing an FDA memorandum that only came to light earlier this year, the company Smith, Kline & French, now GlaxoSmithKline (GSK), ran a clinical trial of the drug in the US involving 875 people, including pregnant women, in 1956 - 57.

Davis hoped life might improve when he was chosen in 2012 to participate in a clinical trial of a drug called ocrelizumab.

Physicians immediately began recruiting hundreds of people for a clinical trial of the drug, and that study is ongoing.

As a proof of principle, the researchers collaborated with Clovis Oncology, a biotech company based in Boulder, Colorado, which is running a clinical trial of drugs known as PARP inhibitors in patients with stage II ovarian cancer.

In collaboration with Vertex, HUB has tested ivacaftor on organoids grown from CF patients who had taken part in a clinical trial of that drug.

Industry representatives argue that the ethical and scientific procedures they currently use for human pesticide tests are no different from those employed in clinical trials of drugs.

One case is a clinical trial of the drug Zidovudine, a medication that was 75 percent effective in preventing HIV positive mothers from transmitting the disease to their unborn children.

In July 2015, his muscles wasting away, Wartman joined a clinical trial of a drug, ibrutinib, approved to treat specific blood cancers.

The Pulmonary - Allergy Drugs Advisory Committee of the FDA evaluated the results of a clinical trial of the drug Pulmozyme on 968 patients.

At our Doheny Eye Institute in a CIRM - supported program, Professor Mark Humayun and David Hinton are planning to trial stem therapies for macular degeneration, and my colleague Michael Kahn has just initiated a phase I clinical trial of a drug for colorectal carcinoma that was developed using a stem cell - based screen.

The first clinical trial of a drug to block vasculogenic mimicry — and thus potentially limit tumor growth — has begun in the United States and Taiwan.

In the first clinical trial of the drug, called G3139, 43 per cent of the 14 patients saw a measurable shrinkage in their tumours after treatment, says Burkhard Jansen of Vienna University.

The next step, Srivastava said, is clinical trials of the drugs as a therapy for asthma and COPD — a process that should be expedited since aldose reductase inhibitors have already undergone Phase III clinical trials for diabetic neuropathy.

Texas Children's Cancer Center is a member of the COG Phase I Consortium, a small and select group of institutions that administer Phase I clinical trials of drugs in early development.

Rigorous experiments in animals have given way to clinical trials of drugs that target the HD gene in people, and there are more techniques for decreasing or eliminating huntingtin on the horizon.

He has invested in four biotech funds, is involved in a clinical trial of a drug for Parkinson's disease, has pledged as much as $ 40 million to the Michael J. Fox Foundation, and has been thinking a lot about the promise of stem cells lately.

In clinical trials of the drug, 13 % of women stopped taking flibanserin due to side effects.