Routine
clinical use of his vaccine forestalled the paralysis and death brought by the dreaded illness
Not exact matches
Written by a world - renown
clinical pharmacologist, Dr. Thomas Hale, this drug reference provides includes everything that is known about the transfer
of various medications into human milk, and the
use of radiopharmaceuticals, the
use of chemotherapeutic agents, and
vaccines in breastfeeding mothers.
The safety
of the
vaccine has been established in large
clinical trials and will be continually monitored as it comes into wider
use,» Ed Yong, health information manager at the charity told politics.co.uk
Tumors typically have a repertoire
of molecular defenses they can
use to suppress or evade immune attacks, which is why cancer
vaccines and immunotherapies have had mixed results in
clinical trials to date.
Study data also indicated that the high - dose
vaccine may provide
clinical benefit for the prevention
of hospitalizations, pneumonia, cardio - respiratory conditions, non-routine medical visits, and medication
use.
While there is a lot
of excitement about the drug, which improved seniors» response to the flu
vaccine in a
clinical trial last year, there are concerns about its side effects, especially with long - term
use.
CDC based its decision for children under 10 to receive two doses on preliminary data from
clinical trials
of the
vaccines being
used in the United States, but he said more complete data should emerge soon.
Granted, different
vaccines are in
use in different locales, but the differences reflect that data from
clinical trials
of various
vaccines in a range
of age brackets is still preliminary.
The Swiss - based pharmaceutical company said that it had made 10 liters
of vaccine that it will
use in pre-
clinical studies and maybe early
clinical trials.
The researchers hope that understanding the level
of virus needed for transmission
of infection will provide a useful reference point for the development
of experimental drugs and
vaccines and could be
used to inform the endpoints for
clinical trials evaluating such interventions.
«New malaria
vaccine effective in
clinical trial: Researchers achieve protection
of up to 100 percent
using fully viable malaria parasites.»
Just a few weeks ago, WHO said that
using any
of the experimental drugs or
vaccines in the pipeline simply wasn't in the cards, because none
of them have been through a phase I
clinical study, the type
of trial in which medical products are tested on healthy volunteers to study their toxicity.
Using a novel synthetic platform for creating
vaccines originally developed in the laboratory
of David Weiner, PhD, a professor
of Pathology and Laboratory Medicine from the Perelman School
of Medicine at the University
of Pennsylvania, a team led by his colleagues at the Johns Hopkins University School
of Medicine, has successfully eradicated precancerous cervical lesions in nearly half
of the women who received the investigational
vaccine in a
clinical trial.
This month at the European Congress
of Clinical Microbiology and Infectious Diseases in London, Herman Goossens, director
of the Laboratory
of Medical Microbiology at the
Vaccine and Infectious Disease Institute
of the University
of Antwerp in Belgium, presented data about one type
of commercial kit often
used to identify particular drug - resistant pathogens.
The Pilot Bioproduction Facility headed by Dr. Kenneth H. Eckels, produced small batches
of vaccine candidates that were
used for the preclinical studies and is currently manufacturing a
vaccine lot for
use in initial human
clinical studies.
Vaccine developers are trying to improve vaccines for transplant recipients and other people with a weak immune system, and the samples used in this study came from a clinical trial of different versions of a flu vaccine in patients on immune - suppressive
Vaccine developers are trying to improve
vaccines for transplant recipients and other people with a weak immune system, and the samples
used in this study came from a
clinical trial
of different versions
of a flu
vaccine in patients on immune - suppressive
vaccine in patients on immune - suppressive drugs.
The U.K. government also noted that «affected African countries will have the primary role
of authorising or allowing
use of investigational
vaccines» and said «buy in» from those communities about the
clinical trials must be obtained as soon as possible.
Comparable antigenicity and immunogenicity
of oligomeric forms
of a novel, acute HIV - 1 subtype C gp145 envelope for
use in preclinical and
clinical vaccine research, doi: 10.1128 / JVI.00412 - 15, J Virol.
Some
of these monoclonal antibodies are already available for
clinical use and cancer
vaccines are still undergoing
clinical trials.
The HIV
Vaccine Trial Network (HVTN) plans to conduct clinical trials in heterosexual adults that will evaluate a prime - boost vaccine regimen similar to that used in RV144 adjusted to target the most common subtype of HIV in the region (subt
Vaccine Trial Network (HVTN) plans to conduct
clinical trials in heterosexual adults that will evaluate a prime - boost
vaccine regimen similar to that used in RV144 adjusted to target the most common subtype of HIV in the region (subt
vaccine regimen similar to that
used in RV144 adjusted to target the most common subtype
of HIV in the region (subtype C).
In this role, Ms. Roxland re-launched and chaired J&J's Ethics Committee, created an enterprise - wide consultation service for teams and individuals confronting complex research ethics issues, and provided guidance on issues such as post-trial access for former research participants, conducting
clinical trials in war - torn regions, testing
of a potential Ebola
vaccine during a public health crisis, commercialization
of stem cell therapies, subject recruitment and withdrawal, and expanded access / compassionate
use.
He is
using lymphocyte receptors as targets for new therapies for lymphoma, and is currently conducting
clinical trials
of lymphoma
vaccines.
NJTV - New Pancreatic Study May Offer Hope for the Future - November 17, 2011 CINJ Deputy Director Dr. Edmund Lattime and Co-Director
of CINJ's Gastrointestinal - Hepatobiliary Oncology Program Dr. Elizabeth Poplin discuss early results to a unique
clinical trial that
uses vaccine therapy to target pancreatic cancer.
Their laboratory was involved in the initial development, characterization, and
clinical testing
of the preventive virus - like particle - based HPV
vaccines that are now
used in three FDA - approved HPV
vaccines.
2015 — Began a Phase 1b
clinical trial
of two experimental Ebola
vaccines in Kampala, Uganda,
using Chimpanzee Adenovirus type 3 vector (ChAd3)
vaccines, co-developed by the VRC, National Institutes
of Allergy and Infectious Diseases (NIAID) and GlaxoSmithKine.
As Head
of Project Leader Unit, Nicolas is in charge
of the pharmaceutical development and subsequent production
of vaccines - for
use in
clinical trials - directly funded by the European
Vaccine Initiative (EVI), and European projects funded from other sources coordinated by EVI.
In addition, the Fletcher group investigates immunity
using the mouse model and aims to develop animal models
of TB disease better able to predict TB
vaccine efficacy in
clinical trials.
PHILADELPHIA -
Using a novel synthetic platform for creating
vaccines originally developed in the laboratory
of David Weiner, PhD, a professor
of Pathology and Laboratory Medicine from the Perelman School
of Medicine at the University
of Pennsylvania, a team led by his colleagues at the Johns Hopkins University School
of Medicine, has successfully eradicated precancerous cervical lesions in nearly half
of the women who received the investigational
vaccine in a
clinical trial.
Recent attempts on extensive trials
of cancer
vaccines,
using viral structures or substructures against several cancers such as cervices, prostate, lung, pancreatic and skin also failed to produce the overall protective
clinical outcomes
He has participated in many
clinical trials, including the
use of innovative
vaccines and treatments in horses.
Numerous
clinical trials involving the
use of melanoma tumor
vaccines have been conducted or are underway.
(Why I Don't
Use Lyme Disease
Vaccines, Meryl P. Littman, VMD, ACVIM; Department
of Clinical Studies School
of Veterinary Medicine, University
of Pennsylvania; Compendium on Continuing Education for the Practicing Veterinarian, November 1997.)