There is, however, to date not enough evidence to suggest that probiotics are of use in treating acute, severe pouchitis — more research is needed into this aspect and indeed into
the clinical use of probiotics for pouchitis in general.
Not exact matches
«The benefits
of probiotics are strain specific, which means formulators need to look at the
clinical studies supporting the exact
probiotic strain
used to determine what benefits to claim, and ensure inclusion rates through the end
of shelf life to support these amounts,» Bush says.
«Also, patients with mild
clinical forms
of ulcerative colitis should be informed that they might
use, with caution, an alternative
probiotic treatment to prevent relapse.»
Areas
of focus include the
clinical and health implications
of using probiotics, potential forensic
uses of microbiome profiles, bioterrorism and biodefense applications, the application
of new technologies from the project, and patenting and privacy issues.
Marteau PR, et al., Protection from Gastrointestinal Diseases with the
Use of Probiotics, American Journal
of Clinical Nutrition73 (2, Suppl 1): 430S - 436S, 2001.
Although there are numerous claimed benefits
of using probiotic supplements, such as maintaining gastrointestinal health, in part by lowering risk
of and severity
of constipation or diarrhea, and improving immune health, including lower risk
of and severity
of acute upper respiratory tract infections, i.e., the common cold, such claims are not all supported by sufficient
clinical evidence.
A review by Dinan et al. encompasses the
clinical basis for the
use of probiotics in mental health with reference to animal studies in which behavioral changes resulted from exposure to bacterial strains such as bifidobacterium and lactobacillus.
There is a need for additional data to be generated to provide proof
of efficacy in
probiotic therapy before these agents can be applied to widespread
clinical use.