Sentences with phrase «clinical use of these approaches»

Not exact matches

Through talking to experts in the field over the past year, Gates said he had identified five areas of need: Understanding better how Alzheimer's unfolds, detecting and diagnosing it earlier, pursuing multiple approaches to trying to halt the disease, making it easier for people to take part in clinical trials of potential new medicines, and using data better.

To achieve this goal, several approaches are envisaged: identifying small populations with severe disease where a medicine's benefit - risk balance could be favorable; making more use of real - world data where appropriate to support clinical trial data; and involving health technology assessment bodies early in development to increase the chance that medicines will be recommended for payment and ultimately covered by national healthcare systems.

«Through the intense focus our 285,000 colleagues bring to helping people live healthier lives and helping make the health system work better for everyone, we have grown to serve more people in more ways than ever, including through innovative uses of advanced technologies, data analytics, and modern clinical approaches that improve quality, lower cost and advance consumer and care provider satisfaction,» David S. Wichmann, CEO of UnitedHealth Group, said in a conference call.

It does not measure other critical brain functions that can be adversely affected by head trauma, such as balance and vision, which is why expert groups [1] recommend a «multifaceted approach to concussion management that emphasizes the use of objective assessment tools aimed at capturing the spectrum of clinical signs and symptoms, cognitive dysfunction, and physical deficits... that are more sensitive to the injury than using any one component alone.»

In an effort to find out, Stephen P. Juraschek, M.D., Ph.D., research and clinical fellow in general internal medicine at the Johns Hopkins University School of Medicine, and his colleagues used data from the DASH (Dietary Approaches to Stop Hypertension) clinical trial, a widely popular and often - cited study whose results were first published in 1997.

Weiss cautioned that this proof - of - principle finding is an early step, with many further studies to be done to verify if this approach will be safe and effective in clinical use.

In a series of side - by - side comparisons, Mooney's team demonstrated that APC - mimetic scaffolds performed better than methods involving commercially available expansion beads (Dynabeads), which are currently used in clinical adoptive cell transfer approaches.

Tissue - based planning systems — using clinical guidelines to determine the optimal breast implant dimensions for individual patients — appear superior to approaches relying more on the patient's or surgeon's preference, according to the study by Drs. William P. Adams, Jr., of University of Texas Southwestern Medical Center, Dallas, and Daniel McKee of McMaster University, Hamilton, Ont., Canada.

Instead of simply tracking what the outlets were publishing and analyzing their impact on public opinion, the researchers took an approach similar to that used in clinical trials to evaluate the effects of new drugs.

His primary clinical and research focus is dementia, with specific areas of interest including biomarkers to assist in the diagnosis and understanding of disease mechanisms for Alzheimer's and Parkinson's disease, and translational research using novel therapeutic approaches.

The MIT researchers have started a company to begin a larger clinical study for validating this approach, and they plan to investigate the possibility of using this technology for other types of cancer.

This is the first JTFPP guideline that was developed using a GRADE (Grading of Recommendations, Assessment, Development and Evaluations) methodology, a very rigorous, systematic, evidence - based approach to making clinical recommendations.

«At Exeter we are already developing specific psychological therapies, running clinical trials of novel drug approaches and using - cutting edge genetic techniques to identify new targets for safe and effective therapies and to allow us to use current treatments in a more focussed way.»

At today's press conference, both Friedmann and Fischer expressed confidence that their approach is on the cusp of mainstream clinical use.

His laboratory is also keenly interested in utilizing high - throughput proteomic approaches for the discovery of biomarkers for diseases such as cancer and exploring the use of proteomic and metabolomic technology for the routine interrogation of clinical samples.

«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.»

«inStem is using a large spectrum of approaches» to both basic research and its clinical application, he said.

More refinement of these approaches are necessary before clinical use, Â but it illustrates how engineered mixtures of progenitor cells and supportive materials are becoming increasingly sophisticated and complicated.

According to Dr. Carter, the findings suggest that future approaches using clinical assessments to identify the specific type of brain dysfunction contributing to a patient's symptoms may allow a more targeted approach to treatment.

«Given the broad and growing use of smartwatches and ready accessibility of downloadable mobile applications, this approach may ultimately be applied to efficiently screen for AF,» said senior author Gregory Marcus, MD, MAS, a UCSF Health cardiologist and director of clinical research in the UCSF Division of Cardiology.

He noted that while no technique has emerged as a proven clinical approach, the use of human rather than rodent cells as demonstrated by Pollok et al. is an important step in advancing the science behind liver cell transplantation.

The clinical sensitivity in detecting clonality in a majority of B - cell malignancies can approach 100 percent when the IGH and IGK assays are used together.

Our team designed a mixed - methods approach, utilizing quantitative surveys and qualitative methods, to examine preferences and motivations of physicians and patients enrolled, evaluate the flow and utilization of genomic information within the clinical interactions, and assess understanding, behavior, medical consequences and healthcare costs associated with the use of WGS in these models of medical practice.

The Cancer Genome Atlas is using genomic, transcriptomic, and epigenomic measurements of cancer cells, coupled with computational approaches and rich clinical data, to understand the dysfunctions that underline the onset, progression, and spread of cancer.

Despite the marginal improvements in survival of patients suffering from malignant glioma treated with gene therapy vectors, the clinical trials conducted so far using viral vectors, in particular adenoviral vectors, have proven that the use of adenoviral vectors is a safe therapeutic approach, even in large, multicenter, phase 3 clinical trials.

Lung Cancer is approached at Penn in a multidisciplinary fashion from both the clinical and research perspective using the infrastructure of the Abramson Cancer Center's interdisciplinary Thoracic Oncology Program (ITOP).

Although clinical trials have collectively shown a disease control rate of approximately 45 percent using this approach in ovarian cancer, they have yet to establish selective benefit in BRCA1 / 2 - deficient cancers, which should generate stronger anti-tumor immune responses given their higher mutation rate.

One approach in clinical trials is to wipe out the patient's immune system using strong doses of chemotherapy with antibodies and then use their own previously banked hematopoietic stem cells (blood forming stem cells) to regenerate the blood system.

While genome editing technology represents a highly promising area to advance the future of therapy for hematologic disorders, critical questions must be addressed to effectively translate this approach into clinical use.

Last month, we published a paper in the BMJ — along with a number of genetic scientists, clinical geneticists and other health specialists — advocating an evidence - based approach that places the emphasis on targeted diagnosis in the short term, and gathering evidence for possible broader uses in future.

The results here reported are consistent with current knowledge concerning the biological and clinical effects of each one of the elements used in the approach described in this study.

The IFN Academy ™ uses a research oriented, evidence - based, systematic yet personalized «case based» approach in teaching health care practitioners how to use IFN for the core clinical imbalances that lie at the root of most chronic health conditions including:

Functional Medicine is an integrative, science - based healthcare approach that treats illness and promotes wellness by focusing on the biochemical processes that go on in the body, and the ways that natural substances such as vitamins and herbs can impact those processes — it is a paradigm shift in medicine that uses recent technological and clinical advances to treat the underlying causes of illness.

The Inflammation Research Foundation was founded in 2003 as a non-profit 501c foundation dedicated to providing support for clinical research projects for the use of innovative nutritional approaches to reduce inflammation that is the underlying cause of many chronic disease conditions.

Research1 shows that there is substantial overlap between clinical features of different hereditary cancer syndromes, further supporting the use of a pan-cancer, multi-gene approach.

All of those approaches are still in clinical use today.

Breathwork is an increasingly popular experiential approach to psychotherapy based on the use of a specific breathing technique, however, claims of positive mental health outcomes rely on anecdotal clinical evidence.

«In 2000, backed by over 35 years of clinical and empirical research, Dr. Neil Clarke Warren transformed the way singles are introduced online when he launched eHarmony - the first relationship service on the Web to use a scientific approach to match highly compatible singles.»

As the National Council for Accreditation of Teacher Education Blue Ribbon Panel noted, «This demanding, clinically based approach will create varied and extensive opportunities for candidates to connect what they learn with the challenge of using it, while under the expert tutelage of skilled clinical educators.»

However, clinical research has shown a new approach to canine and feline periodontal disease prevention that can be used in conjunction with, or as an alternative to brushing of the teeth, Oravet.

This article examines these approaches towards resolving disputes over surplus embryos and considers whether they support the express objectives of the AHRA and Quebec's Act Respecting Clinical and Research Activities Relating to Assisted Procreation (Act Respecting Assisted Procreation) to protect the health and well - being of women, to promote the principle of free and informed consent and to recognize that women are more directly affected than men by the use of assisted reproductive technologies (ARTs).

I am inclined toward a Humanistic, Cognitive Behavioral and Family Systems approach, but am capable of being effective using all clinical frameworks.

New Directions for Youth (North Hollywood, CA) 2009 — 2011 Marriage and Family Therapy Intern • Conducted initial interviews and assessments to develop treatment and recovery plans for program participants as well as involved family members • Obtained family, social, and employment data along with medical and mental health treatment information for use in process • Served as member of multi-disciplinary team to review client cases, treatment approaches, clinical issues, participant progress and treatment recommendations • Integrate training and various applicable techniques into treatment plans designed to address mental, emotional and family disorders or conditions • Prepared and maintained clinical case files for use in diagnostic evaluations and the monitoring of progress • Coordinated all continuity of care and other treatment - related services with probation officers, community service professionals and healthcare personnel

I offer individual therapy using a variety of clinical approaches.

Blending conventional and alternative approaches, I use a variety of clinical styles which will be most helpful to each client to assist in building the strength to identify and achieve their goals.»

I am a Licensed Clinical Psychologist who uses a biopsychosocial approach to my assessment of a person's mental health concerns.

«Through the use of clinical expertise, compassionate communication and discerning intuition, I assist clients utilizing a Solution - Focused and Cognitive Behavioral approach.

Being skilled at seeing each individual as unique with their own strengths, our staff uses a wide array of medical and clinical experience to offer a proactive approach to treatment that promotes self - awareness as a vehicle to emotional well - being.

She is interested in using objective measures of outcome to demonstrate clinical changes and in using these data to guide further development of the treatment approach used in this program.

I have extensive experience working with people of color and LGBTQIA individuals and use an identity affirming clinical approach.»