Sentences with phrase «clinically meaningful effects»

In general, of course, we want large effect sizes in our practice, and we want clinically meaningful effects.

Not exact matches

If the average treatment effect had not been clinically meaningful, we would not have combined trials.
If the average treatment effect was not clinically meaningful, we would not combine trials.
As there was clinical heterogeneity sufficient to expect that the underlying treatment effects differed between trials, or where substantial statistical heterogeneity was detected, we used random - effects meta - analysis to produce an overall summary, if an average treatment effect across trials was considered clinically meaningful.
«The magnitude of the treatment effect of FCM on the 6MWT distance, is robust and clinically meaningful,» noted Professor Ponikowski.
Advanced melanoma patients successfully treated with a combination of nivolumab and ipilimumab may endure severe side effects, but they do not suffer any clinically meaningful changes in health - related quality of life.
Although the difference in patient mortality between male and female physicians was modest, an observed effect size of a 0.43 - percentage point difference or a relative risk reduction of 4 % in mortality is arguably a clinically meaningful difference.
It has a clinically meaningful anxiolytic effect and alleviates anxiety related disturbed sleep.»
Although the thermogenic effect of CCRT has the potential to produce significant effects on these metabolic targets as well as on fat absorption and energy intake, possibly via its impact on the gut microbiota and gene expression, a clinically meaningful outcome also depends on compliance by the subjects.
According to Jacobson and Truax, 39 statistically significant and large effect sizes do not necessarily translate into clinically meaningful changes (ie, an intervention effect may be statistically significant but clinically trivial).
Effect sizes (ESs) were calculated for all trends and statistically significant findings; (ES ≈ 0.5 (d)-RRB- was considered clinically meaningful.
The meta - analyses showed the most pronounced effect sizes for parent — child interaction and maternal sensitivity, whereas the effects on child behaviour and cognitive development were either small or not significant; however, small effect sizes can have meaningful impact on population - level outcomes.60 The non-significant outcomes for internalising and externalising behaviours were also small, but may be clinically relevant for large, at - risk populations.
Intervention effected significant and clinically meaningful symptomatic amelioration in OCD, depression, and anxiety symptoms.
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