Sentences with phrase «clinically meaningful impact»

But «overall, I wish more attention was paid to the fact that this small trial was to examine safety and efficacy and that much more needs to be done to make statements regarding clinically meaningful impact on disease,» Vandross said.

The authors concluded that the doula's presence has a clinically meaningful impact on anxiety and pain levels in first - time mothers giving birth.

Not exact matches

Although the thermogenic effect of CCRT has the potential to produce significant effects on these metabolic targets as well as on fat absorption and energy intake, possibly via its impact on the gut microbiota and gene expression, a clinically meaningful outcome also depends on compliance by the subjects.

The meta - analyses showed the most pronounced effect sizes for parent — child interaction and maternal sensitivity, whereas the effects on child behaviour and cognitive development were either small or not significant; however, small effect sizes can have meaningful impact on population - level outcomes.60 The non-significant outcomes for internalising and externalising behaviours were also small, but may be clinically relevant for large, at - risk populations.