Sentences with phrase «clinically relevant research»

Emotion dysregulation is often invoked as an important construct for understanding risk for psychopathology, but specificity of domains of emotion regulation in clinically relevant research is often lacking.

JSER has priority areas and we make decisions based on whether papers are likely to directly and substantially affect clinical practice or public health policy, or have implications of broad general interest for the direction of future, directly clinically relevant research.

«What you need is scientifically sound, clinically relevant research to understand what does work, and in order to do that you need to measure the many dimensions impacted by pain,» said Dr. Lascelles.

Objective: This review sought to identify rigorous, clinically relevant research studies that provide high - quality evidence that therapeutic fasting regimens are clinically beneficial to humans.

So when she launched her own lab as a 29 - year - old assistant professor at Harvard Medical School in 2008, she continued to study RNA — but with the clear goal of performing clinically relevant research.

Meeting children who had lost eyes to retinoblastoma motivated Dyer to build a clinically relevant research program.

Not exact matches

Extracting clinically relevant information pertinent to a complex disease process, drawing from a data set of 19,000 genes, required a creative rather than systematic research approach.

«One of the broader goals of our research is to make regenerative treatments more accessible and clinically relevant by developing easy, efficient and cost - effective ways to engineer human cells and tissues,» said Shyni Varghese, a bioengineering professor at UC San Diego and senior author of the study.

Lab scientists who've met patients say the experience enriches their research and points them toward more clinically relevant questions.

«Despite the identification of circulating tumor cells (CTCs) and cell - free DNA (cfDNA) as biomarkers capable of providing clinically relevant information in cancer patients, at present their identification is not routinely used in clinical practice,» explains Silvia Morbelli, MD, PhD, of the IRCCS San Martino — IST National Cancer Research Institute and University of Genoa in Genoa, Italy.

«Prospective longitudinal studies like the one here... are able to provide reliable conclusions on such a clinically and highly relevant research question.

«Further research is needed to determine if these bacterial differences are clinically relevant for the millions of women with OAB and the doctors who treat them.»

BBSRC cuts come at a time when the funding for basic neuroscience in the United Kingdom is already threatened with a move by the Medical Research Council to fund more clinically relevant science, explains Colin Blakemore, a neuroscientist at the University of Oxford and former head of the Medical Research Council.

«Further research will reveal whether these antibodies are the mark of a clinically relevant subset of patients and, if so, whether immunosuppressive therapies can effectively treat children with these debilitating illnesses.»

Also, it would allow me to formulate fundamental research questions based on clinically relevant problems, take these to the lab, and eventually translate the research findings back to the clinic.

The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.

Currently I'm most excited about the latter because I have started to bring my line of research to be more relevant to what I do clinically.

Sponsored by the Glenn Foundation for Medical Research in collaboration with AFAR, the two - year, $ 200,000 BIG award is designed to provide timely support to a small number of research projects that are building on early discoveries that show translational potential for clinically relevant strategies, treatments and therapeutics that address human aging and heaResearch in collaboration with AFAR, the two - year, $ 200,000 BIG award is designed to provide timely support to a small number of research projects that are building on early discoveries that show translational potential for clinically relevant strategies, treatments and therapeutics that address human aging and hearesearch projects that are building on early discoveries that show translational potential for clinically relevant strategies, treatments and therapeutics that address human aging and healthspan.

In 2008, the British Medical Journal published research concluding acupuncture can be a significant, clinically relevant adjunct to IVF, relaxing the uterus and increasing blood flow for the successful implantation of an embryo.

There are so many unique stool tests on the market that give interesting information, but it really isn't clinically relevant at this time due to the research we currently have.

Dr. Gonzalez» research has aimed to develop and utilize large animal models to translate lab bench findings into clinically relevant therapeutic interventions that benefit both human and veterinary patients.

Many of the scales demonstrated weak psychometrics in at least one of the following ways: (a) lack of psychometric data [i.e., reliability and / or validity; e.g., HFQ, MASC, PBS, Social Adjustment Scale - Self - Report (SAS - SR) and all perceived self - esteem and self - concept scales], (b) items that fall on more than one subscale (e.g., CBCL - 1991 version), (c) low alpha coefficients (e.g., below.60) for some subscales, which calls into question the utility of using these subscales in research and clinical work (e.g., HFQ, MMPI - A, CBCL - 1991 version, BASC, PSPCSAYC), (d) high correlations between subscales (e.g., PANAS - C), (e) lack of clarity regarding clinically - relevant cut - off scores, yielding high false positive and false negative rates (e.g., CES - D, CDI) and an inability to distinguish between minor (i.e., subclinical) and major (i.e., clinical) «cases» of a disorder (e.g., depression; CDI, BDI), (f) lack of correspondence between items and DSM criteria (e.g., CBCL - 1991 version, CDI, BDI, CES - D, (g) a factor structure that lacks clarity across studies (e.g., PSPCSAYC, CASI; although the factor structure is often difficult to assess in studies of pediatric populations, given the small sample sizes), (h) low inter-rater reliability for interview and observational methods (e.g., CGAS), (i) low correlations between respondents such as child, parent, teacher [e.g., BASC, PSPCSAYC, CSI, FSSC - R, SCARED, Connors Ratings Scales - Revised (CRS - R)-RSB-, (j) the inclusion of somatic or physical symptom items on mental health subscales (e.g., CBCL), which is a problem when conducting studies of children with pediatric physical conditions because physical symptoms may be a feature of the condition rather than an indicator of a mental health problem, (k) high correlations with measures of social desirability, which is particularly problematic for the self - related rating scales and for child - report scales more generally, and (l) content validity problems (e.g., the RCMAS is a measure of anxiety, but contains items that tap mood, attention, peer interactions, and impulsivity).

How we differentiate normative from non-normative manifestations of aggression is therefore a clinically relevant and scientifically necessary goal for etiologic research and the prevention of violence.

Prior research has established the influence of maternal depression on the child's behavioral and emotional health3, 27,28 and its relevance for pediatric practice.29, 30 Several studies have analyzed the independent effects on children of mothers» and fathers» mental health, but few have examined the more clinically relevant question of how the mental health of parents jointly influences child outcomes.16, 31,32 The largest study of the joint effects of mothers» and fathers» mental health on children was a population - based study of twins and their parents.16 Similar to our results, the combination of maternal and paternal depression was associated with the largest increase in children's depressive symptoms.