This grand supported by funding from the National Institute of Mental Health,
clinicaltrials.gov Identifier NCT00347269
Clinical Trial:
ClinicalTrials.gov Identifier: NCT02874833
Clinical Trial:
ClinicalTrials.gov identifier: NCT03256682
[
ClinicalTrials.gov Identifier: NCT02817074]
Publications automatically indexed to this study by
ClinicalTrials.gov Identifier (NCT Number):
In the phase II CALM trial (
ClinicalTrials.gov identifier: NCT01227551), [20] 57 patients with stage IIIC (42.1 %) or stage IV (57.9 %) melanoma and at least 1 injectable dermal, cutaneous, subcutaneous, or lymph node lesion received 10 series of multi-intratumoral CVA21 injections.
The phase II part of a phase Ib / II study (
ClinicalTrials.gov identifier: NCT02263508; MASTERKEY - 265)[24] assessing the safety and efficacy of T - VEC in combination with the PD - 1 — blocking antibody pembrolizumab in previously untreated, unresected stage IIIB / IV melanoma is evaluating confirmed ORR by irRECIST at week 24.
For more information on this study (
ClinicalTrials.gov identifier no.
Currently, lymphadenectomy is an eligibility requirement for cutting - edge adjuvant therapy trials such as Southwest Oncology Group (SWOG) 1404 (
ClinicalTrials.gov identifier: NCT02506153), which randomizes stage III melanoma patients to an anti — programmed death 1 antibody or standard - of - care adjuvant therapy (high - dose interferon or high - dose ipilimumab).
(
clinicaltrials.gov identifier: 01458730)
A larger ongoing phase 3 study (SONAR;
ClinicalTrials.gov identifier NCT01858532) will shed more light on the kidney and cardiovascular protective effects of atrasentan.
Several early stage clinical trials using autologous infusions of ZFN - generated CCR5 - modified CD4 + T cells are currently underway (
clinicaltrials.gov identifiers NCT00842634, NCT01252641, NCT01044654).
Not exact matches
Details are available at the NIH's
ClinicalTrials.gov website,
identifier: NCT01792024.
«The study was approved by the local ethics committee, written informed consent was obtained, and the study was registered at
ClinicalTrials.gov (
identifier: NCT000123456).»