Sentences with phrase «clomipramine hydrochloride»

Clomipramine hydrochloride, the active ingredient in Clomicalm, binds to the serotonin uptake receptor and prevents it from removing excess serotonin.

Like many drugs, there are a number of names by which Clomipramine can go by, including Anafanil (made by Novartis,) Clomicalm (manufactured by Novartis) or the generic Clomipramine Hydrochloride.

While clomipramine hydrochloride can cause lethargy in dogs (see Adverse Reactions) its mode of action is not as a sedative.

Clomipramine hydrochloride is 3 - chloro - 5 [3 -(dimethyl - amino) propyl]-10,11-dihydro5H-dibenz [b, f] azepine monohydrochloride.

A single - dose crossover study involving 12 dogs evaluated clomipramine hydrochloride bioavailability after IV (2 mg / kg) and oral (4 mg / kg) administration in either a fed or fasted state.

Clomipramine hydrochloride's capacity to inhibit re-uptake of serotonin in the central nervous system is believed to be the primary mechanism of action.

Clomipramine hydrochloride reduces the clinical signs of separation anxiety by affecting serotonergic and noradrenergic neuronal transmission in the central nervous system.

The molecular weight of clomipramine hydrochloride is 351.3.

Clomicalm Tablets are oblong, light brown in color and contain clomipramine hydrochloride formulated together with meat components.

The administration of clomipramine hydrochloride in the presence of food resulted in an increase in the rate and extent of drug absorption as shown in the following table (mean ± SD):

Clomicalm (clomipramine hydrochloride) Tablets belong to the dibenzazepine class of tricyclic antidepressants.