Sentences with phrase «clonal gene rearrangements»
Our NGS kits are used to detect clonal gene rearrangements, somatic hypermutations and for the study of MRD.
https://www.invivoscribe.com/ Not exact matches
They also include a comprehensive bioinformatics package, enabling you to identify the DNA sequence, clonal prevalence, and V - J family identity for each gene rearrangement.
Since leukemias and lymphomas originate from the malignant transformation of individual lymphoid cells, all leukemias and lymphomas generally share one or more cell - specific or «clonal» antigen receptor gene rearrangements.
To identify and track clonal T cell receptor (TRB) gene rearrangements using next - generation sequencing with the Illumina MiSeq ®
Invivoscribe products identify clonal rearrangements within the immunoglobulin and T - cell receptor genes, which helps identify clonal B - and T - cell populations.
These assays, developed for use with specific Next Generation Sequencing (NGS) platforms, combine optimized, proprietary multiplex PCR master mixes with a software package that converts NGS output data to an easily interpretable form, enabling you to identify the DNA sequence, clonal prevalence, and V - J gene identity for each gene rearrangement.