For therapeutic or embryo cloning, the objective is not to create adult animals, but to extract stem cells for research from
the cloned embryos created.
Not exact matches
Tonight I ask you to pass legislation to prohibit the most egregious abuses of medical research: human
cloning in all its forms,
creating or implanting
embryos for experiments,
creating human - animal hybrids, and buying, selling, or patenting human
embryos.
Benedict argued that non-conjugal reproduction such as in vitro fertilization had
created «new problems» ¯ the freezing of human
embryos, for instance, and the selective abortion of medically implanted
embryos, together with pre-implantation diagnosis, embryonic stem - cell research, and attempts at human
cloning.
After months of discussion, the group drafted a call to ban all human
cloning and to limit ESCR to the use of the «excess»
embryos created in the process of in vitro fertilization (IVF).
Unlike the controversial method of tissue harvesting that requires some human
embryos to be destroyed, the new
cloning technique can use a patient's own skin cells — combined with an unfertilized human egg — to
create tissue with a DNA match.
For reproductive
cloning - which
creates animals with an identical genetic make - up to an already existing animal - the
embryo must then be transferred to a host body, in which to grow.
However, in 2007 Professor Wilmut announced that he had decided to change to an alternative method of research pioneered in Japan, known as direct reprogramming or «de-differentiation», which could
create human embryonic cells without using human eggs or
cloning human
embryos.
Besides the low efficiency of
cloning — just 1.7 per cent of
embryos came to term — another challenge to
creating transgenic dogs is controlling where in the nuclear DNA a foreign gene lands.
To solve this, West proposed «therapeutic
cloning» — taking the nucleus out of a patient's cell, transferring it into an egg cell to
create a
cloned embryo, then using that
embryo to derive patient - matched stem - cell lines.
There should be a complete ban on the implantation of a human
embryo created by the application of
cloning technology into a womb, or any treatment of such a human
embryo intended to result in its development into a viable infant.
Varmus pointed out that a special review group he
created in 1994 to give advice on
embryo research had already judged human
cloning to be «repugnant» — a view he endorsed.
Using
cloning technology, their «Lazarus Project»
created an
embryo of the extinct gastric - brooding frog.
The paper not only seemed to validate the group's claim a year earlier that it had
created a single cell line from a
cloned human
embryo, but it also reported a huge increase in efficiency for the technique.
A U.S. company has received two British patents that appear to grant it commercial rights to human
embryos created by
cloning.
Some scientists, such as Kevin Eggan at Harvard, were disappointed that NIH didn't open the door to the use of
embryos created for research purposes — including through somatic cell nuclear transfer (
cloning) and parthenogenesis (from an unfertilized egg).
Stem cell researchers call them «a major step in the right direction,» although some were disappointed that NIH didn't open the door to the use of
embryos created for research purposes — including through somatic cell nuclear transfer (
cloning) and parthenogenesis (from an unfertilized egg).
In most cases, dozens of
clone embryos must be
created before one yields a viable pregnancy.
In a 2009 study, University of Georgia at Athens
cloning expert Steve Stice
created 29 chimeric piglets by injecting pluripotent stem cells into pig
embryos before implanting them into a surrogate womb.
Antinori said his team would begin
creating cloned embryos «within a month or so».
Using stem cells from the resulting
embryos, Wakayama and his team were able to
create clones that grew into fertile adult mice.
A key difference, however, is that Dolly's donor cell came from adult udder cells growing in lab dishes (see ScienceNOW, 24 February), while the donor cells used to
create the monkey
clones came from early
embryos.
If you can
create an
embryo genetically identical to the adult — that is, a
clone — you can harvest immune - compatible cells to replace any tissue you might want without fear of rejection.
And if the cells prove to be functional enough for nuclear transfer but not for producing offspring, they might refute one of the main arguments against therapeutic
cloning: that it
creates embryos only to destroy them.
Opponents said that the measure should have banned somatic cell nuclear transfer; it criminalized only the «implantation» of an
embryo into a woman to
create a human
clone.
But the favored reprogramming technique, somatic cell nuclear transfer (SCNT), otherwise known as research
cloning, is fraught with ethical pitfalls as well as technical difficulties because it entails
creating a human
embryo by inserting an adult cell nucleus into an ooctye.
One team in Japan, and another in the US, have independently shown it is possible to produce embryonic - like stem cells directly from a patient's own skin cells without having to
create and destroy a
cloned human
embryo first.
Today, Roe said three outside labs have determined those two lines were not derived from
cloned embryos, but instead came from
embryos created by in vitro fertilization at MizMedi Hospital in Seoul, which collected oocytes for Hwang's research.
The 13 sheep in the new study were
created from 2005 to 2007, when biologist Keith Campbell, a key member of the Dolly team, was trying to improve
cloning —
creating more viable
embryos to implant in the wombs of surrogate mothers, more pregnancies, and more live offspring.
Benedict argued that non-conjugal reproduction such as in vitro fertilization had
created «new problems» ¯ the freezing of human
embryos, for instance, and the selective abortion of medically implanted
embryos, together with pre-implantation diagnosis, embryonic stem - cell research, and attempts at human
cloning.
A team of scientists from the New York Stem Cell Foundation Laboratory
created 13 early - stage human
embryos that were partial genetic
clones of diabetic patients.
One of those teams
created a
cloned embryo from the somatic cells of a diabetic patient; this
embryo was then destroyed in order to generate an insulin - producing embryonic stem cell line.
After more debate, the government may change this allowing
cloned human cells and
embryos to be
created for research purposes as long as they are destroyed after 14 days.
The research team at Oregon Health & Science University used skin cells from rhesus macaque monkeys to
create the
cloned embryos.
Most recently, in February 2003, Senator Arlen Specter, Republican of Pennsylvania, and others introduced legislation that would expand research options by allowing cells to be newly isolated from
embryos, including
cloned embryos — those
created for research purposes only and not through fertilization.
This includes a ban on
embryo splitting and other techniques that might
create a
clone without fertilization.
Scientists respond as maverick
cloning scientist Dr Panos Zavos announces successful experiments to
create cloned embryos using DNA from dead people.