«The rise of «superbugs» leaves the clinical community with a rapidly dwindling number of options to treat infectious disease and to prevent the spread of resistant bacteria in, for example, hospital settings,» explains Professor Vincent O'Flaherty of the National University of Ireland Galway,
co-corresponding author on the study, recently published in Frontiers in Microbiology.
«The tumor cells are smart,» said Wei Guo,
co-corresponding author on the study and a professor of biology in Penn's School of Arts and Sciences.
«In just one shot you get your structure,» said Northwestern's Yonggang Huang, one of three
co-corresponding authors on the study.
«Humans vary in their DNA sequences, and what is taken as the «normal» DNA sequence for reference can not account for all these differences,» says Stuart Orkin, MD, of Dana - Farber Boston Children's Cancer and Blood Disorders Center and
co-corresponding author on the study with Matthew Canver, an MD - PhD student at Harvard Medical School.
This would stop a cell with a mutation cold in its tracks right after it is born,» said Alejandro Chavez, Ph.D., a first and
co-corresponding author on the study, who as a Postdoctoral Fellow at HMS was co-mentored by Church and Collins and is now Assistant Professor at Columbia University.
«The Vienna team of Dr. Javier Martinez, also
a co-corresponding author on the study, could actually show that mutations in CLP1 affect tRNA biogenesis and that CLP1 mutant brain stem cells become more apoptotic (invoking cell death).
«Before our study, the most basic aspects of the reaction between gas - phase IEPOX and anthropogenic sulfate particles and the effect of particle coatings were unknown,» said Dr. Alla Zelenyuk, a physical chemist and
co-corresponding author on the study.
Not exact matches
«One of the ways that superfluidity manifests is through the formation of quantum vortices, but they have never been experimentally observed in droplets,» said Andrey Vilesov, professor of chemistry and physics at the USC Dornsife Collge of Letters, Arts and Sciences and
co-corresponding author of the
study, which appears in Science
on August 22.
«Every new technology is an opportunity for
studying cells and tissues in greater detail,» said Broad core institute member Aviv Regev, a
co-corresponding author on the paper, director of the Klarman Cell Observatory (KCO) at the Broad and the institute's Cell Circuits Program, and — along with Broad institute member and Infectious Disease and Microbiome Program co-director Ramnik Xavier — a
co-corresponding author on the paper.
Our
study opens the door for novel modalities of treatment based
on small molecules that could cross biological barriers
on their own,» said
co-corresponding author Joseph F. Arboleda - Velasquez, MD, PhD, assistant scientist at Schepens Eye Research Institute.