Sentences with phrase «co-primary endpoints»

Patients with acute coronary syndrome undergoing angioplasty who received the anticoagulant drug bivalirudin did not show significant improvements in either of two co-primary endpoints — a composite of rate of death, heart attack or stroke at 30 days, or a composite of those events plus major bleeding — as compared to patients receiving standard anticoagulation therapy, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

In addition, the study had a higher - than - usual bar for statistical significance due to its inclusion of two co-primary endpoints instead of only one.

The study failed to meet both of its co-primary endpoints in that it did not show a significant benefit of steroid treatment over placebo in terms of either the overall rate of death or a composite metric that included death, heart attack, stroke, new renal failure or respiratory failure.