Sentences with phrase «co-senior study author»

«Previous studies from the last couple of decades have suggested that bacteria in the baby's gastrointestinal tract might be associated with these conditions,» explained co-senior study author Susan Lynch.

In this study, we have identified individual components of these circuits, but next we would like to see how they are connected in the central nervous system,» co-senior study author Cynthia Moss of Johns Hopkins University said in a statement.

In a previous study, Lonard and co-senior study author Bert O'Malley of Baylor College of Medicine screened a large number of compounds to identify SRC - inhibiting molecules that kill a wide variety of cancer cells and inhibit tumor growth in animal models.

Huang and co-senior study author Zhijian Su of Jinan University reasoned that the direct conversion of adult skin cells into Leydig cells would be a faster, safer regenerative medicine approach.

«We had a hunch that rapidly growing tumors can «outgrow» their blood supply, resulting in dead tumor cells that might spill their viral antigens amongst the living cancer cells,» said co-senior study author Arturo Casadevall, chair of Einstein's Microbiology & Immunology department.

Beales and co-senior study author João Ruggiero Neto of São Paulo State University in Brazil suspected that the reason might have something to do with the unique properties of cancer cell membranes.

«Cancer therapies that attack the lipid composition of the cell membrane would be an entirely new class of anticancer drugs,» says co-senior study author Paul Beales, of the University of Leeds in the UK.

Not exact matches

«This study reveals for the first time a comprehensive picture of all active alleles in different tissues — we have uncovered the first complete allelome» Florian Pauler, now at ISTA (Institute of Science and Technology Austria) and co-senior author, adds.

«This is a big step in determining the identity of key components of the molecular machinery that converts sound waves into electrical signals in the inner ear,» said the study's co-senior author, Gregory Frolenkov, of the Department of Physiology at the University of Kentucky.

«We are in the process of elucidating the exact mechanism by which B2M works,» said Saul A. Villeda, PhD, a UCSF Faculty Fellow and co-senior author of the new study.

«Our research is the first to study Zika infection in a mouse model that transmits the virus in a way similar to humans,» explains Alysson R. Muotri, Ph.D., professor and director of the Stem Cell Program at UC San Diego and co-senior author of the study.

As Saaïd Safieddine, CNRS Director of Research at the Institut Pasteur and co-senior author of the study with Prof. Christine Petit (head of the Genetics & physiology hearing unit at the Institut Pasteur), explains, «we have just shown that it is possible to partially correct a specific form of hereditary hearing loss accompanied by balance problems using local gene therapy performed after the embryogenesis of the ear, which is primarily affected by the mutation responsible for the disorder.

Instead, we gave it a vehicle to travel in, making it better capable of navigating the terrain inside the inner ear and accessing previously resistant cells,» said Maguire, who is also co-senior author on the study.

Mirkin and Paller are co-senior authors of the study.

The study, published in Biological Psychiatry, was led by co-senior authors Tianxi Cai, Sc.D., and Roy H. Perlis, M.D..

«Previous studies had used an older method to analyze patients» inflammatory markers,» explained co-senior author George Kuchel, MD, a geriatrician at the University of Connecticut Health Center.

Sheng Ding, PhD, a senior investigator in the Roddenberry Stem Cell Center at Gladstone and co-senior author on the study, adds, «This new cellular reprogramming and expansion paradigm is more sustainable and scalable than previous methods.

«Fascinating genetic studies had been done on SMCHD1 that linked the gene to FSHD2, a rare muscular dystrophy involving the interaction of multiple genetic sites, but it had never been connected to craniofacial abnormalities,» says Michael Talkowski, PhD, of the MGH Center for Human Genetic Research, co-senior author of the Nature Genetics paper.

«Our results demonstrate for the first time that human adult skin cells can be used to efficiently and rapidly generate functional pancreatic cells that behave similar to human beta cells,» says Matthias Hebrok, PhD, director of the Diabetes Center at UCSF and a co-senior author on the study.

Professor Gary Blissard of the Boyce Thompson Institute at Cornell University, and Professor Michael Kanost of Kansas State University, initiated the study and are co-senior authors on this large international project that included 114 researchers from 50 institutions and 11 countries.

Other Dana - Farber contributors to the study include Levi Garraway, MD, PhD, a co-senior author, Mary - Ellen Taplin, MD, Mark Pomerantz, MD, and Massimo Loda, MD, director of Dana - Farber's Center for Molecular Oncologic Pathology.

Co-senior author Professor Jennifer Nichols at the Wellcome Trust - Medical Research Council Stem Cell Institute, said: «Our data allow us to study gene activity in individual cells to an unprecedented level of precision.

In this latest study, the investigators collaborated with a team at the University of Michigan led by co-senior author Brian Pierchala to further learn about the role of p75 in the development of sensory neurons.

«This paper is a great example of how chemistry can help make step changes in biology,» says Matthew Dalby, a professor of cell engineering at the University of Glasgow and co-senior author on the study with Ulijn.

«For someone like myself, in this kind of work, this is the kind of result that you get to see once in your career,» said study co-senior author Philippe Armand, MD, PhD, medical oncologist in the Hematologic Oncology Treatment Center at Dana - Farber.

George Hajishengallis, Thomas W. Evans Centennial Professor in Penn's School of Dental Medicine's Department of Biology, and John D. Lambris, Dr. Ralph and Sallie Weaver Professor of Research Medicine in the Perelman School of Medicine's Department of Pathology and Laboratory Medicine, were co-senior authors on the study, the result of years of collaboration.

She has been seen by Dr. Marni J. Falk of the Children's Hospital of Philadelphia, who is a co-senior author of the study.

«What makes these results especially encouraging is that they were achieved in patients who had exhausted other treatment options,» said the study's co-senior author, Margaret Shipp, MD, chief, Division of Hematologic Neoplasia at Dana - Farber.

«This is an exciting study of a very rare bone disorder that not only identified the responsible mutation in half of the patients, but uncovered fundamental information about the role of a cancer - related gene in the metabolic pathways of normal bone,» said study co-senior author Joan Marini, Ph.D., M.D., of NICHD.

«Transplantation tolerance appears to be a resilient and persistent state, even though it can be transiently overcome,» said Anita Chong, PhD, professor of transplantation surgery at the University of Chicago and co-senior author of the study.

«The methods for achieving transplantation tolerance differ between mice and humans, but the mechanisms that maintain it are likely shared,» said Marisa Alegre, MD, PhD, professor of medicine at the University of Chicago and co-senior author on the study.

«This study demonstrates the potential of combining functional profiling of cells with the characterizations of cancer genomes via next generation sequencing,» said co-senior author Jill P. Mesirov, PhD, professor and associate vice chancellor for computational health sciences at UC San Diego School of Medicine.

«The idea is that when fat cells (adipocytes) interact with environmental agents — in this case, bacterial toxins — they then trigger a chronic inflammatory process,» says Patrick Schlievert, Ph.D., UI professor and head of microbiology and co-senior author of a new study published in the journal PLOS ONE.

It's a very consistent difference and was discovered in the 1920's,» said Dr. Baran Sumer, Associate Professor of Otolaryngology, and co-senior author of the study.

Christian Griesinger, a professor at the Max Planck Institute for Biophysical Chemistry and co-senior author of the study, noted, «The drug is able to reach the brain when taken orally.

However, our study offers evidence that anle138b has potential for neuroprotection,» said André Fischer, a senior researcher at the German Center for Neurodegenerative Diseases and the University Medical Center Göttingen, who is also a co-senior author of the study.

If we want to use biomaterials to regenerate those tissues, we need elasticity and flexibility,» said Annabi, a co-senior author of the study.

«This is the first drug molecule that can regulate memory loss by directly blocking ions from leaking through nerve cell membranes,» said Ratnesh Lal, a professor of bioengineering at the University of California San Diego and co-senior author of the study.

Boehme conducted the study with fellow University of Utah physicists: first author and postdoctoral fellow Hans Malissa; research professor and co-senior author John Lupton, who also is on the faculty of the University of Regensburg, Germany; distinguished professor Z. Valy Vardeny; professor Brian Saam; graduate students Marzieh Kavand and David Waters; and postdoctoral fellow Kipp van Schooten.

«This collaboration has been about each partner sharing their unique resources and expertise — samples, protocols, analyses, insights — to help understand and fight Zika,» said Thiago Moreno L. Souza, a study co-senior author and senior research scientist at Fundação Oswaldo Cruz in Rio de Janiero, Brazil.

«Each population has a particular genetic «palette», said Dr Daniel Falush of the Max Planck Institute for Evolutionary Anthropology in Leipzig, co-senior author of the study.

Working together was critical to reaching that goal,» said study co-senior author Bronwyn MacInnis, associate director of malaria and viral genomics in the Broad's Infectious Disease and Microbiome Program.

Freeman and colleagues including lead author Justin Centi and co-senior author Alice Cronin - Golomb, PhD, director of the Vision and Cognition Laboratory and Center for Clinical Biopsychology and a professor of psychological and brain sciences at Boston University, divided 55 volunteers into three study groups: 18 patients with both PD and OH, 19 patients with PD but without OH, and 18 control participants with neither PD nor OH.

«There are several vaccines in human trials right now, but to date, none of them has been shown to protect during pregnancy,» said Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine at Washington University School of Medicine in St. Louis, and the study's co-senior author.

«This is a very large scale study using a new, innovative statistical method,» said study co-senior author Kenneth S. Kendler, M.D., professor of psychiatry, and human and molecular genetics in the Virginia Commonwealth University School of Medicine, and an internationally recognized psychiatric geneticist.

«To better understand what happens when cells are overwhelmed with fat during obesity, we first have to understand how the system normally deals with fluctuations in lipids,» said Tobias Walther, professor of genetics and complex diseases at Harvard Chan and co-senior author of the study.

«Rett syndrome patients have a mutation that makes macrophages hyper - sensitive to specific stress signals,» said Vladimir Litvak, PhD, assistant professor of microbiology and physiological systems and co-senior author of the study.

«When treating patients, clinicians must balance risks and benefits,» said Marc A. Pfeffer, MD, PhD, BWH Division of Cardiovascular Medicine, Department of Medicine, study co-senior author.

«Some of the earliest farming was practiced in the Levant, including Israel and Jordan, and in the Zagros mountains of Iran — two edges of the Fertile Crescent,» said Ron Pinhasi, associate professor of archaeology at University College Dublin and co-senior author of the study.

Khalil served as co-senior author on the study with Radhika Atit, PhD, professor of biology at Case Western Reserve University School of Medicine.